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grant_code:"T32DA07290"

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Current Database

  • EMDB [4]

Current status

  • REL [4]

Sample type

  • Complex [4]
  • Ligand [2]
  • Protein [2]

Organism

  • Homo sapiens [4]
  • Mus musculus [2]

EM Method

  • Single-particle [4]

Resolution

  • ≥ 3Å and < 4Å [2]
  • ≥ 4Å and < 5Å [2]

Model molecular weight

  • 250-500 kDa [2]

Release Date

  • 2019 [4]

Author by name

  • Cabuco R [4]
  • Gharpure A [4]
  • Hibbs RE [4]
  • Howard RJ [4]
  • Lindahl E [4]
  • Noviello CM [4]
  • Teng J [4]
  • Walsh Jr Rm [4]
  • Zaveri NT [4]
  • Zhuang Y [4]
  • Walsh RM [2]

Author by ORCID

  • Gharpure A [4]
  • Zaveri NT [4]
  • Walsh Jr Rm [4]
  • Zhuang Y [4]

Journal

  • NEURON [4]

Software

  • RELION [4]
  • GCTF [2]

Microscope

  • FEI TITAN KRIOS [3]
  • FEI TALOS ARCTICA [1]

Electron Source

  • FIELD EMISSION GUN [4]

Film or detector model

  • GATAN K2 SUMMIT 4K X 4K [3]
  • GATAN K3 6K X 4K [1]

External links

  • AlphaFold DB [2]
  • ChEBI [2]
  • ChEMBL [2]
  • Complex Portal [2]
  • DrugBank [2]
  • Gene Ontology [2]
  • InterPro [2]
  • PDB [2]
  • PDBe-Kb [2]
  • Pfam [2]
  • UniProt [2]
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Showing 1 - 4 of 4. Page 1 of 1
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EMD-20487
Download Map
3D View
Human alpha3beta4 nicotinic acetylcholine receptor in complex with nicotine
Release date: Sept. 11, 2019
Resolution: 3.34 Å
EM Method: Single-particle
Fitted PDBs: 6pv7
Q-score: 0.501

Gharpure A, Teng J, Zhuang Y, Noviello CM, Walsh Jr RM, Cabuco R, Howard RJ, Zaveri NT, Lindahl E, Hibbs RE

Neuron (2019) 104 pp. 501- [ DOI: doi:10.1016/j.neuron.2019.07.030 Pubmed: 31488329 ]

EMD-20488
Download Map
3D View
Human alpha3beta4 nicotinic acetylcholine receptor in complex with AT-1001
Release date: Sept. 11, 2019
Resolution: 3.87 Å
EM Method: Single-particle
Fitted PDBs: 6pv8
Q-score: 0.416

Gharpure A, Teng J, Zhuang Y, Noviello CM, Walsh Jr RM, Cabuco R, Howard RJ, Zaveri NT, Lindahl E, Hibbs RE

Neuron (2019) 104 pp. 501- [ DOI: doi:10.1016/j.neuron.2019.07.030 Pubmed: 31488329 ]

EMD-20489
Download Map
3D View
Human alpha3beta4 nicotinic acetylcholine receptor in complex with nicotine in saposin nanodiscs without CHS
Release date: Sept. 11, 2019
Resolution: 4.7 Å
EM Method: Single-particle

Gharpure A, Teng J, Zhuang Y, Noviello CM, Walsh Jr RM, Cabuco R, Howard RJ, Zaveri NT, Lindahl E, Hibbs RE

Neuron (2019) 104 pp. 501-511.e6 [ DOI: doi:10.1016/j.neuron.2019.07.030 Pubmed: 31488329 ]

EMD-20490
Download Map
3D View
Human alpha3beta4 nicotinic acetylcholine receptor in complex with AT-1001 in saposin nanodiscs
Release date: Sept. 11, 2019
Resolution: 4.55 Å
EM Method: Single-particle

Gharpure A, Teng J, Zhuang Y, Noviello CM, Walsh Jr RM, Cabuco R, Howard RJ, Zaveri NT, Lindahl E, Hibbs RE

Neuron (2019) 104 pp. 501-511.e6 [ DOI: doi:10.1016/j.neuron.2019.07.030 Pubmed: 31488329 ]

Sort by: Download
Showing 1 - 4 of 4. Page 1 of 1
Display:
Statistics
×

Download











































Preview first 10
Download

Filter By

Current Database

  • EMDB [4]

Current status

  • REL [4]

Sample type

  • Complex [4]
  • Ligand [2]
  • Protein [2]

Organism

  • Homo sapiens [4]
  • Mus musculus [2]

EM Method

  • Single-particle [4]

Resolution

  • ≥ 3Å and < 4Å [2]
  • ≥ 4Å and < 5Å [2]

Model molecular weight

  • 250-500 kDa [2]

Release Date

  • 2019 [4]

Author by name

  • Cabuco R [4]
  • Gharpure A [4]
  • Hibbs RE [4]
  • Howard RJ [4]
  • Lindahl E [4]
  • Noviello CM [4]
  • Teng J [4]
  • Walsh Jr Rm [4]
  • Zaveri NT [4]
  • Zhuang Y [4]
  • Walsh RM [2]

Author by ORCID

  • Gharpure A [4]
  • Zaveri NT [4]
  • Walsh Jr Rm [4]
  • Zhuang Y [4]

Journal

  • NEURON [4]

Software

  • RELION [4]
  • GCTF [2]

Microscope

  • FEI TITAN KRIOS [3]
  • FEI TALOS ARCTICA [1]

Electron Source

  • FIELD EMISSION GUN [4]

Film or detector model

  • GATAN K2 SUMMIT 4K X 4K [3]
  • GATAN K3 6K X 4K [1]

External links

  • AlphaFold DB [2]
  • ChEBI [2]
  • ChEMBL [2]
  • Complex Portal [2]
  • DrugBank [2]
  • Gene Ontology [2]
  • InterPro [2]
  • PDB [2]
  • PDBe-Kb [2]
  • Pfam [2]
  • UniProt [2]