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grant_code:"R35GM126907"

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Current Database

  • EMDB [22]

Current status

  • REL [22]

Sample type

  • Complex [22]
  • DNA [4]
  • Ligand [4]
  • Protein [4]

Organism

  • Saccharomyces cerevisiae [22]
  • Synthetic construct [4]
  • Homo sapiens [1]

EM Method

  • Single-particle [22]

Resolution

  • ≥ 2Å and < 3Å [5]
  • ≥ 3Å and < 4Å [16]
  • ≥ 4Å and < 5Å [1]

Model molecular weight

  • 500-1000 kDa [4]

Release Date

  • 2025 [22]

Author by name

  • Allwein B [22]
  • Bahng S [22]
  • Batra S [22]
  • Bruning JG [22]
  • Devbhandari S [22]
  • Hite R [22]
  • Hite RK [22]
  • Kumar C [22]
  • Lee CM [22]
  • Marians KJ [22]
  • Remus D [22]

Author by ORCID

  • Remus D [22]
  • Allwein B [22]
  • Hite RK [22]
  • Bruning JG [22]
  • Batra S [22]
  • Lee CM [22]

Journal

  • SCIENCE [22]

Software

  • CRYOSPARC [22]

Microscope

  • TFS KRIOS [22]

Electron Source

  • FIELD EMISSION GUN [22]

Film or detector model

  • GATAN K3 6K X 4K [22]

External links

  • AlphaFold DB [4]
  • ChEBI [4]
  • ChEMBL [4]
  • DrugBank [4]
  • Gene Ontology [4]
  • InterPro [4]
  • PDB [4]
  • PDBe-Kb [4]
  • Pfam [4]
  • UniProt [4]
  • Complex Portal [2]
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Showing 1 - 10 of 22. Page 1 of 3
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EMD-47470
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Cryo-EM structure of yeast CMG helicase stalled at G4-containing DNA template, state 1
Release date: March 26, 2025
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 9e2w
Q-score: 0.527

Batra S, Allwein B, Kumar C, Devbhandari S, Bruning JG, Bahng S, Lee CM, Marians KJ, Hite RK, Remus D

Science (2025) 387 pp. eadt1978-eadt1978 [ DOI: doi:10.1126/science.adt1978 Pubmed: 40048517 ]

EMD-47472
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Cryo-EM structure of yeast CMG helicase stalled at G4-containing DNA template, state 3
Release date: March 26, 2025
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 9e2y
Q-score: 0.513

Batra S, Allwein B, Kumar C, Devbhandari S, Bruning JG, Bahng S, Lee CM, Marians KJ, Hite RK, Remus D

Science (2025) 387 pp. eadt1978-eadt1978 [ DOI: doi:10.1126/science.adt1978 Pubmed: 40048517 ]

EMD-47473
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Cryo-EM structure of human CMG helicase stalled at G4-containing DNA template
Release date: March 26, 2025
Resolution: 2.6 Å
EM Method: Single-particle
Fitted PDBs: 9e2z
Q-score: 0.645

Batra S, Allwein B, Kumar C, Devbhandari S, Bruning JG, Bahng S, Lee CM, Marians KJ, Hite RK, Remus D

Science (2025) 387 pp. eadt1978-eadt1978 [ DOI: doi:10.1126/science.adt1978 Pubmed: 40048517 ]

EMD-47747
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C-tier local refinement of human CMG G4 stall state
Release date: March 26, 2025
Resolution: 2.46 Å
EM Method: Single-particle

Batra S, Allwein B, Kumar C, Devbhandari S, Bruning JG, Bahng S, Lee CM, Marians KJ, Hite RK, Remus D

Science (2025) 387 pp. eadt1978-eadt1978 [ DOI: doi:10.1126/science.adt1978 Pubmed: 40048517 ]

EMD-47748
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3D View
N-tier local refinement of human CMG G4 stall state
Release date: March 26, 2025
Resolution: 2.53 Å
EM Method: Single-particle

Batra S, Allwein B, Kumar C, Devbhandari S, Bruning JG, Bahng S, Lee CM, Marians KJ, Hite RK, Remus D

Science (2025) 387 pp. eadt1978-eadt1978 [ DOI: doi:10.1126/science.adt1978 Pubmed: 40048517 ]

EMD-47749
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3D View
Cdc45-GINS local refinement of human CMG G4 stall state
Release date: March 26, 2025
Resolution: 2.41 Å
EM Method: Single-particle

Batra S, Allwein B, Kumar C, Devbhandari S, Bruning JG, Bahng S, Lee CM, Marians KJ, Hite RK, Remus D

Science (2025) 387 pp. eadt1978-eadt1978 [ DOI: doi:10.1126/science.adt1978 Pubmed: 40048517 ]

EMD-47751
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3D View
Yeast CMG-CTM G4 stall state 1 C-tier local refinement
Release date: March 26, 2025
Resolution: 3.15 Å
EM Method: Single-particle

Batra S, Allwein B, Kumar C, Devbhandari S, Bruning JG, Bahng S, Lee CM, Marians KJ, Hite RK, Remus D

Science (2025) 387 pp. eadt1978-eadt1978 [ DOI: doi:10.1126/science.adt1978 Pubmed: 40048517 ]

EMD-47753
Download Map
3D View
Yeast CMG G4 stall state 1, N-tier local refinement
Release date: March 26, 2025
Resolution: 3.06 Å
EM Method: Single-particle

Batra S, Allwein B, Kumar C, Devbhandari S, Bruning JG, Bahng S, Lee CM, Marians KJ, Hite RK, Remus D

Science (2025) 387 pp. eadt1978-eadt1978 [ DOI: doi:10.1126/science.adt1978 Pubmed: 40048517 ]

EMD-47754
Download Map
3D View
Yeast CMG G4 stall state 1 Cdc45-GINS local refinement
Release date: March 26, 2025
Resolution: 3.12 Å
EM Method: Single-particle

Batra S, Allwein B, Kumar C, Devbhandari S, Bruning JG, Bahng S, Lee CM, Marians KJ, Hite RK, Remus D

Science (2025) 387 pp. eadt1978-eadt1978 [ DOI: doi:10.1126/science.adt1978 Pubmed: 40048517 ]

EMD-47755
Download Map
3D View
Yeast CMG G4 stall state 1 Tof1-Csm3 local refinement
Release date: March 26, 2025
Resolution: 3.16 Å
EM Method: Single-particle

Batra S, Allwein B, Kumar C, Devbhandari S, Bruning JG, Bahng S, Lee CM, Marians KJ, Hite RK, Remus D

Science (2025) 387 pp. eadt1978-eadt1978 [ DOI: doi:10.1126/science.adt1978 Pubmed: 40048517 ]

Sort by: Download
Showing 1 - 10 of 22. Page 1 of 3
Display:
Statistics
×

Download











































Preview first 10
Download

Filter By

Current Database

  • EMDB [22]

Current status

  • REL [22]

Sample type

  • Complex [22]
  • DNA [4]
  • Ligand [4]
  • Protein [4]

Organism

  • Saccharomyces cerevisiae [22]
  • Synthetic construct [4]
  • Homo sapiens [1]

EM Method

  • Single-particle [22]

Resolution

  • ≥ 2Å and < 3Å [5]
  • ≥ 3Å and < 4Å [16]
  • ≥ 4Å and < 5Å [1]

Model molecular weight

  • 500-1000 kDa [4]

Release Date

  • 2025 [22]

Author by name

  • Allwein B [22]
  • Bahng S [22]
  • Batra S [22]
  • Bruning JG [22]
  • Devbhandari S [22]
  • Hite R [22]
  • Hite RK [22]
  • Kumar C [22]
  • Lee CM [22]
  • Marians KJ [22]
  • Remus D [22]

Author by ORCID

  • Remus D [22]
  • Allwein B [22]
  • Hite RK [22]
  • Bruning JG [22]
  • Batra S [22]
  • Lee CM [22]

Journal

  • SCIENCE [22]

Software

  • CRYOSPARC [22]

Microscope

  • TFS KRIOS [22]

Electron Source

  • FIELD EMISSION GUN [22]

Film or detector model

  • GATAN K3 6K X 4K [22]

External links

  • AlphaFold DB [4]
  • ChEBI [4]
  • ChEMBL [4]
  • DrugBank [4]
  • Gene Ontology [4]
  • InterPro [4]
  • PDB [4]
  • PDBe-Kb [4]
  • Pfam [4]
  • UniProt [4]
  • Complex Portal [2]