Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!
EMD-47472
Cryo-EM structure of yeast CMG helicase stalled at G4-containing DNA template, state 3
EMD-47472
Composite mapSingle-particle
3.2 Å
Deposition: 23/10/2024Map released: 26/03/2025
Last modified: 26/03/2025
Sample Organism:
Saccharomyces cerevisiae W303,
synthetic construct
Sample: Yeast CMG-CTM G4 stall state 3
Fitted models: 9e2y
Deposition Authors: Allwein B
,
Batra S
,
Remus D
,
Hite R
Sample: Yeast CMG-CTM G4 stall state 3
Fitted models: 9e2y
Deposition Authors: Allwein B
,
Batra S
,
Remus D
,
Hite R
G-quadruplex-stalled eukaryotic replisome structure reveals helical inchworm DNA translocation.
Batra S
,
Allwein B
,
Kumar C,
Devbhandari S,
Bruning JG
,
Bahng S,
Lee CM
,
Marians KJ,
Hite RK
,
Remus D
(2025) Science , 387 , eadt1978 - eadt1978
,
Allwein B
,
Kumar C,
Devbhandari S,
Bruning JG
,
Bahng S,
Lee CM
,
Marians KJ,
Hite RK
,
Remus D
(2025) Science , 387 , eadt1978 - eadt1978
Grant Support:
- National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS): R35GM152094 (United States)
- National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS): R35GM126907 (United States)
- National Institutes of Health/National Cancer Institute (NIH/NCI): P30 CA008748 (United States)
