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EMD-47473

Composite map
Single-particle
2.6 Å
EMD-47473
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Deposition: 23/10/2024
Map released: 26/03/2025
Last modified: 26/03/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-47473
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9e2z summary report (pdf.gz) Map and 9e2z FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM structure of human CMG helicase stalled at G4-containing DNA template

EMD-47473

Composite map
Single-particle
2.6 Å
EMD-47473
3D View Gallery
Deposition: 23/10/2024
Map released: 26/03/2025
Last modified: 26/03/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, synthetic construct, Saccharomyces cerevisiae W303
Sample: Human CMG, G4 stall state
Fitted models: 9e2z

Deposition Authors: Allwein B , Batra S , Remus D , Hite R
G-quadruplex-stalled eukaryotic replisome structure reveals helical inchworm DNA translocation.
Batra S , Allwein B , Kumar C, Devbhandari S, Bruning JG , Bahng S, Lee CM , Marians KJ, Hite RK , Remus D
(2025) Science , 387 , eadt1978 - eadt1978
PUBMED: 40048517
DOI: doi:10.1126/science.adt1978
ISSN: 1095-9203
ASTM: SCIEAS