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author:"Stoops B"

Filter By

Current Database

  • EMDB [4]

Current status

  • REL [4]

Sample type

  • Complex [4]
  • Ligand [4]
  • Protein [4]

Organism

  • Human respiratory syncytial virus [3]
  • Synthetic construct [2]
  • Human respiratory syncytial virus [1]

EM Method

  • Single-particle [4]

Resolution

  • ≥ 2Å and < 3Å [3]
  • ≥ 3Å and < 4Å [1]

Model molecular weight

  • 250-500 kDa [4]

Release Date

  • 2025 [4]

Author by name

  • Grosse S [4]
  • Jacoby E [4]
  • Jonckers THM [4]
  • Lutter FH [4]
  • Pieters S [4]
  • Sharma S [4]
  • Stoops B [4]
  • Tran MT [4]
  • Yin Y [4]
  • Yu X [4]
  • Van Vlijmen H [4]
  • Abeywickrema P [3]
  • Anson B [3]
  • Bhaumik A [3]
  • Carbajo RJ [3]
  • Conceicao-neto N [3]
  • De Bruyn S [3]
  • Fung A [3]
  • Garcia MO [3]
  • Hu L [3]
  • Jin Z [3]
  • Jonckers T [3]
  • Kalin JH [3]
  • Lemmens C [3]
  • Lozada K [3]
  • Miller R [3]
  • Oehlrich D [3]
  • Piassek M [3]
  • Rombouts G [3]
  • Smith-monroy C [3]
  • Tomaso S [3]
  • Wong V [3]
  • Carney SM [2]
  • Cooymans L [2]
  • Fino R [2]
  • Kesteleyn B [2]
  • Krosky DJ [2]
  • Mason SW [2]
  • Neefs JM [2]
  • Ortiz-meoz RF [2]
  • Patrick AN [2]
  • Simmons N [2]
  • Vetrano I [2]
  • Xie X [2]
  • Adhikary S [1]
  • Alcazar J [1]
  • Carney C [1]
  • Carney S [1]
  • Krosky D [1]
  • Martinez C [1]
  • Mason S [1]
  • Neefs J-M [1]
  • Patrick A [1]
  • Rigaux P [1]
  • Roymans D [1]
  • Tan E [1]

Author by ORCID

  • Van Vlijmen H [3]
  • Kalin JH [3]
  • Jonckers THM [3]
  • Tran MT [3]
  • Fino R [2]
  • Oehlrich D [2]
  • Krosky DJ [2]
  • Kesteleyn B [2]
  • Rombouts G [2]
  • Yin Y [1]
  • Alcazar J [1]
  • Roymans D [1]

Journal

  • J MED CHEM [2]
  • ACS MED.CHEM.LETT. [1]
  • J VIROL [1]

Microscope

  • TFS GLACIOS [2]
  • TFS KRIOS [2]

Electron Source

  • FIELD EMISSION GUN [4]

Film or detector model

  • FEI FALCON IV 4K X 4K [2]
  • GATAN K3 6K X 4K [2]

External links

  • Gene Ontology [4]
  • PDB [4]
  • PDBe-Kb [4]
  • Pfam [4]
  • UniProt [4]
  • ChEBI [2]
  • ChEMBL [2]
  • DrugBank [2]
  • InterPro [2]
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EMD-47927
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3D View
CryoEM Structure Of Respiratory Syncytial Virus Polymerase in complex with Novel Non-Nucleoside Inhibitor Compound 16
Release date: Sept. 24, 2025
Resolution: 2.79 Å
EM Method: Single-particle
Fitted PDBs: 9ecv
Q-score: 0.608

Carney SM, Grosse S, Yin Y, Tran MT, Kalin JH, Jacoby E, Fung A, Simmons N, Xie X, Bhaumik A, Carbajo RJ, Piassek M, Miller R, Hu L, Lemmens C, Lutter FH, Pieters S, Rombouts G, Vetrano I, Oehlrich D, Tomaso S, Lozada K, Garcia MO, Anson B, De Bruyn S, Smith-Monroy C, Neefs JM, Conceicao-Neto N, Kesteleyn B, Fino R, Stoops B, van Vlijmen H, Patrick AN, Yu X, Wong V, Krosky DJ, Abeywickrema P, Ortiz-Meoz RF, Mason SW, Jin Z, Sharma S, Jonckers THM

J Med Chem (2025) 68 pp. 6407-6430 [ Pubmed: 40042938 DOI: doi:10.1021/acs.jmedchem.4c02906 ]

EMD-47931
Download Map
3D View
CryoEM map of Respiratory Syncytial Virus Polymerase with Non-Nucleoside Inhibitor compound 21
Release date: Sept. 24, 2025
Resolution: 2.72 Å
EM Method: Single-particle
Fitted PDBs: 9ed2
Q-score: 0.617

Carney SM, Grosse S, Yin Y, Tran MT, Kalin JH, Jacoby E, Fung A, Simmons N, Xie X, Bhaumik A, Carbajo RJ, Piassek M, Miller R, Hu L, Lemmens C, Lutter FH, Pieters S, Rombouts G, Vetrano I, Oehlrich D, Tomaso S, Lozada K, Garcia MO, Anson B, De Bruyn S, Smith-Monroy C, Neefs JM, Conceicao-Neto N, Kesteleyn B, Fino R, Stoops B, van Vlijmen H, Patrick AN, Yu X, Wong V, Krosky DJ, Abeywickrema P, Ortiz-Meoz RF, Mason SW, Jin Z, Sharma S, Jonckers THM

J Med Chem (2025) 68 pp. 6407-6430 [ Pubmed: 40042938 DOI: doi:10.1021/acs.jmedchem.4c02906 ]

EMD-48846
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3D View
CryoEM structure Of Respiratory Syncytial Virus Polymerase with novel non-nucleoside inhibitor compound 22
Release date: May 28, 2025
Resolution: 2.72 Å
EM Method: Single-particle
Fitted PDBs: 9n36
Q-score: 0.615

Kalin JH, Yin Y, Tran MT, Piassek M, Fung A, Grosse S, Jacoby E, Bhaumik A, Adhikary S, Miller R, Lemmens C, Lutter FH, Pieters S, Cooymans L, Rombouts G, Oehlrich D, Tomaso S, Lozada K, Garcia MO, Anson B, De Bruyn S, Smith-Monroy C, Neefs J-M, Conceicao-Neto N, Stoops B, van Vlijmen H, Patrick A, Yu X, Wong V, Krosky D, Abeywickrema P, Mason S, Jin Z, Jonckers THM, Sharma S

J Virol (2025) 99 pp. e0017825-e0017825 [ Pubmed: 40454903 DOI: doi:10.1128/jvi.00178-25 ]

EMD-45296
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3D View
EM map Of Respiratory Syncytial Virus Polymerase in complex with JNJ-2729
Release date: Jan. 8, 2025
Resolution: 3.24 Å
EM Method: Single-particle
Fitted PDBs: 9c7y
Q-score: 0.502

Tran MT, Grosse S, Carbajo RJ, Jacoby E, Yin Y, Yu X, Martinez C, Stoops B, Cooymans L, Hu L, Lutter FH, Pieters S, Tan E, Alcazar J, Roymans D, van Vlijmen H, Rigaux P, Sharma S, Jonckers THM

Acs Med.Chem.Lett. (2024) 15 pp. 1549-1558 [ DOI: doi:10.1021/acsmedchemlett.4c00272 Pubmed: 39291020 ]

Sort by: Download
Showing 1 - 4 of 4. Page 1 of 1
Display:
Statistics
×

Download











































Preview first 10
Download

Filter By

Current Database

  • EMDB [4]

Current status

  • REL [4]

Sample type

  • Complex [4]
  • Ligand [4]
  • Protein [4]

Organism

  • Human respiratory syncytial virus [3]
  • Synthetic construct [2]
  • Human respiratory syncytial virus [1]

EM Method

  • Single-particle [4]

Resolution

  • ≥ 2Å and < 3Å [3]
  • ≥ 3Å and < 4Å [1]

Model molecular weight

  • 250-500 kDa [4]

Release Date

  • 2025 [4]

Author by name

  • Grosse S [4]
  • Jacoby E [4]
  • Jonckers THM [4]
  • Lutter FH [4]
  • Pieters S [4]
  • Sharma S [4]
  • Stoops B [4]
  • Tran MT [4]
  • Yin Y [4]
  • Yu X [4]
  • Van Vlijmen H [4]
  • Abeywickrema P [3]
  • Anson B [3]
  • Bhaumik A [3]
  • Carbajo RJ [3]
  • Conceicao-neto N [3]
  • De Bruyn S [3]
  • Fung A [3]
  • Garcia MO [3]
  • Hu L [3]
  • Jin Z [3]
  • Jonckers T [3]
  • Kalin JH [3]
  • Lemmens C [3]
  • Lozada K [3]
  • Miller R [3]
  • Oehlrich D [3]
  • Piassek M [3]
  • Rombouts G [3]
  • Smith-monroy C [3]
  • Tomaso S [3]
  • Wong V [3]
  • Carney SM [2]
  • Cooymans L [2]
  • Fino R [2]
  • Kesteleyn B [2]
  • Krosky DJ [2]
  • Mason SW [2]
  • Neefs JM [2]
  • Ortiz-meoz RF [2]
  • Patrick AN [2]
  • Simmons N [2]
  • Vetrano I [2]
  • Xie X [2]
  • Adhikary S [1]
  • Alcazar J [1]
  • Carney C [1]
  • Carney S [1]
  • Krosky D [1]
  • Martinez C [1]
  • Mason S [1]
  • Neefs J-M [1]
  • Patrick A [1]
  • Rigaux P [1]
  • Roymans D [1]
  • Tan E [1]

Author by ORCID

  • Van Vlijmen H [3]
  • Kalin JH [3]
  • Jonckers THM [3]
  • Tran MT [3]
  • Fino R [2]
  • Oehlrich D [2]
  • Krosky DJ [2]
  • Kesteleyn B [2]
  • Rombouts G [2]
  • Yin Y [1]
  • Alcazar J [1]
  • Roymans D [1]

Journal

  • J MED CHEM [2]
  • ACS MED.CHEM.LETT. [1]
  • J VIROL [1]

Microscope

  • TFS GLACIOS [2]
  • TFS KRIOS [2]

Electron Source

  • FIELD EMISSION GUN [4]

Film or detector model

  • FEI FALCON IV 4K X 4K [2]
  • GATAN K3 6K X 4K [2]

External links

  • Gene Ontology [4]
  • PDB [4]
  • PDBe-Kb [4]
  • Pfam [4]
  • UniProt [4]
  • ChEBI [2]
  • ChEMBL [2]
  • DrugBank [2]
  • InterPro [2]