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author:"Kobilka BK"

Filter By

Current Database

  • EMDB [229]
  • EMPIAR [8]

Current status

  • REL [237]

Sample type

  • Protein [219]
  • Complex [216]
  • Ligand [124]
  • Cellular component [13]

Organism

  • Homo sapiens [228]
  • Mus musculus [37]
  • Lama glama [19]
  • Synthetic construct [8]
  • Rattus norvegicus [5]
  • Human cytomegalovirus [4]
  • Bos taurus [3]
  • (no species) [2]
  • Human cytomegalovirus [1]
  • Epstein-barr virus (strain gd1) [1]
  • Oryctolagus cuniculus [1]

EM Method

  • Single-particle [229]

Resolution

  • ≥ 2Å and < 3Å [15]
  • ≥ 3Å and < 4Å [190]
  • ≥ 4Å and < 5Å [23]
  • ≥ 6Å and < 8Å [1]

Model molecular weight

  • 50-100 kDa [26]
  • 100-250 kDa [112]
  • 250-500 kDa [1]

Release Date

  • 2025 [3]
  • 2024 [177]
  • 2023 [12]
  • 2022 [18]
  • 2021 [6]
  • 2020 [8]
  • 2019 [9]
  • 2018 [2]
  • 2017 [2]

Author by name

  • Kobilka BK [230]
  • Skiniotis G [199]
  • Hilger D [171]
  • Seven AB [171]
  • Gmeiner P [169]
  • Papasergi-scott MM [169]
  • Panova O [166]
  • Gao Y [164]
  • Eskici G [162]
  • Hildebrand PW [162]
  • Casiraghi M [161]
  • Maul L [161]
  • Batebi H [160]
  • He F [160]
  • Perez-hernandez G [160]
  • Wang H [29]
  • Krishna Kumar K [22]
  • Xu J [22]
  • Qu Q [20]
  • Latorraca NR [17]
  • Maeda S [17]
  • Koehl A [16]
  • O Brien Es [16]
  • Zhang C [15]
  • Dror RO [14]
  • Robertson MJ [14]
  • Isacoff EY [13]
  • Habrian C [12]
  • Marqusee S [12]
  • Montabana E [12]
  • Inoue A [11]
  • Feng D [10]
  • Hu H [10]
  • Sun B [10]
  • Kato HE [9]
  • Kobilka TS [9]
  • Mathiesen JM [9]
  • Suomivuori CM [9]
  • Zhang Y [9]
  • Huang W [8]
  • Du Y [7]
  • Hubner H [7]
  • Majumdar S [7]
  • Barros-alvarez X [6]
  • Garcia KC [6]
  • Showalter AD [6]
  • Sloop KW [6]
  • Tsutsumi N [6]
  • Waghray D [6]
  • Weis WI [6]
  • Willard FS [6]
  • Appourchaux K [5]
  • Bueno AB [5]
  • Che T [5]
  • Chen Q [5]
  • Coghlan MP [5]
  • Fonseca R [5]
  • Ho JD [5]
  • Jude KM [5]
  • Stutsman C [5]
  • Sun X [5]
  • Velasco A [5]
  • Vieth M [5]
  • Voegele M [5]
  • Zhang L [5]
  • Zhao J [5]
  • Aihara E [4]
  • Alsina-fernandez J [4]
  • Aydin D [4]
  • Brown RA [4]
  • Cameron MD [4]
  • Carpenter JW [4]
  • Chu M [4]
  • Diberto JF [4]
  • Ding L [4]
  • Dunbar JD [4]
  • Emmerson PJ [4]
  • Hu Y [4]
  • Jin C [4]
  • Kaindl J [4]
  • Mohammed FA [4]
  • Moyers JS [4]
  • Niu X [4]
  • Paggi JM [4]
  • Roth BL [4]
  • Suter TM [4]
  • Tao Y [4]
  • Tarrasch J [4]
  • Varga BR [4]
  • Wang Q [4]
  • Cao S [3]
  • Chen G [3]
  • Deupi X [3]
  • Dutta S [3]
  • Eans SO [3]
  • El Daibani A [3]
  • Heng J [3]
  • Kong F [3]
  • Kumar KK [3]
  • Laermans T [3]

Author by ORCID

  • Kobilka BK [218]
  • Skiniotis G [185]
  • Gmeiner P [169]
  • Hilger D [166]
  • Papasergi-scott MM [165]
  • Gao Y [163]
  • Batebi H [160]
  • Panova O [160]
  • He F [160]
  • Perez-hernandez G [160]
  • Hildebrand PW [160]
  • Xu J [17]
  • O'brien ES [16]
  • Latorraca NR [16]
  • Maeda S [12]
  • Krishna Kumar K [12]
  • Marqusee S [11]
  • Isacoff EY [11]
  • Robertson MJ [10]
  • Zhang Y [9]
  • Du Y [7]
  • Majumdar S [7]
  • Inoue A [7]
  • Mathiesen JM [7]
  • Sloop KW [6]
  • Garcia KC [6]
  • Tsutsumi N [6]
  • Qu Q [6]
  • Dror RO [6]
  • Sun B [5]
  • Appourchaux K [5]
  • Zhao J [5]
  • Coghlan MP [5]
  • Che T [5]
  • Hubner H [5]
  • Fonseca R [5]
  • Chen Q [5]
  • Hu Y [4]
  • Roth BL [4]
  • Jin C [4]
  • Kato HE [4]
  • Suomivuori CM [4]
  • Aydin D [4]
  • Bueno AB [4]
  • Mohammed FA [4]
  • Diberto JF [4]
  • Tao Y [4]
  • Brown RA [4]
  • Moyers JS [4]
  • Barros-alvarez X [3]
  • Wang N [3]
  • Meyerowitz JG [3]
  • Kong F [3]
  • Yan C [3]
  • Mclaughlin JP [3]
  • Toyoda Y [3]
  • Zhu A [3]
  • Dutta S [3]
  • Steyaert J [3]
  • Weis WI [3]
  • Huang W [3]
  • Rangari VA [3]
  • Kumar KK [3]
  • Liu X [3]
  • Deupi X [3]
  • Scheerer P [2]
  • Paisdzior S [2]
  • Mielke T [2]
  • Wang HW [2]
  • Pradhan AA [2]
  • Madasu MK [2]
  • Biebermann H [2]
  • Huang XP [2]
  • Slivicki RA [2]
  • Willard FS [2]
  • Burger J [2]
  • Peddada TN [2]
  • Mwirigi J [2]
  • Gereau 4Th Rw [2]
  • Schacherl M [2]
  • Schertler GFX [2]
  • Hilal T [2]
  • Kwiatkowski D [2]
  • Awad-agbaria Y [2]
  • Heyder NA [2]
  • Al-hasani R [2]
  • Faouzi A [2]
  • Ramos-gonzalez N [2]
  • Kuhnen P [2]
  • Schmidt A [2]
  • Dawson R [2]
  • Cameron MD [2]
  • Katritch V [2]
  • Beck-sickinger AG [2]
  • Speck D [2]
  • Brennan PC [1]
  • Nucci N [1]
  • Furness SGB [1]
  • Sexton PM [1]
  • Coudrat T [1]

Journal

  • NATURE [196]
  • PNAS [8]
  • NAT COMMUN [7]
  • SCI ADV [6]
  • NAT CHEM BIOL [5]
  • BIORXIV [4]
  • CELL [3]
  • SCIENCE [3]
  • ANGEW CHEM INT ED ENGL [2]
  • CELL REP [2]
  • CELL RES [2]
  • TO BE PUBLISHED [2]
  • IMMUNITY [1]

Software

  • CRYOSPARC [168]
  • RELION [19]
  • FREALIGN [2]
  • CISTEM [1]

Microscope

  • FEI TITAN KRIOS [221]
  • TFS KRIOS [8]

Electron Source

  • FIELD EMISSION GUN [229]

Film or detector model

  • GATAN K3 6K X 4K [155]
  • GATAN K2 SUMMIT 4K X 4K [43]
  • GATAN K3 BIOQUANTUM 6K X 4K [21]
  • GATAN K2 QUANTUM 4K X 4K [5]
  • FEI FALCON IV 4K X 4K [3]
  • FEI FALCON III 4K X 4K [2]

EMPIAR Experiment type

  • EMDB [8]

EMPIAR Image category

  • MICROGRAPHS - MULTIFRAME [8]

External links

  • AlphaFold DB [219]
  • PDBe-Kb [219]
  • UniProt [219]
  • EMPIAR [164]
  • Gene Ontology [139]
  • InterPro [139]
  • PDB [139]
  • Pfam [139]
  • ChEMBL [86]
  • ChEBI [82]
  • DrugBank [78]
  • EMDB [8]
  • CATH [5]
  • SCOP2 [4]
Sort by: Download
Showing 1 - 10 of 237. Page 1 of 24
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EMD-44925
Download Map
3D View
Structure of the LM189-Bound beta2AR-Gi Complex
Release date: May 28, 2025
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 9buy
Q-score: 0.521

Casiraghi M, Wang H, Brennan PC, Habrian C, Hubner H, Schmidt MF, Maul L, Pani B, Bahriz SMFM, Xu B, Staffen N, Assafa TE, Chen B, White E, Sunahara RK, Inoue A, Xiang YK, Lefkowitz RJ, Isacoff EY, Nucci N, Gmeiner P, Lerch MT, Kobilka BK

Sci Adv (2025) 11 pp. eadq3971-eadq3971 [ Pubmed: 40106559 DOI: doi:10.1126/sciadv.adq3971 ]

EMD-44199
Download Map
3D View
Biased agonist bound CB1-Gi structure
Release date: March 5, 2025
Resolution: 2.86 Å
EM Method: Single-particle
Fitted PDBs: 9b54
Q-score: 0.584

Rangari VA, O'Brien ES, Powers AS, Slivicki RA, Bertels Z, Appourchaux K, Aydin D, Ramos-Gonzalez N, Mwirigi J, Lin L, Mangutov E, Sobecks BL, Awad-Agbaria Y, Uphade MB, Aguilar J, Peddada TN, Shiimura Y, Huang XP, Folarin-Hines J, Payne M, Kalathil A, Varga BR, Kobilka BK, Pradhan AA, Cameron MD, Kumar KK, Dror RO, Gereau 4th RW, Majumdar S

Nature (2025) 640 pp. 265-273 [ DOI: doi:10.1038/s41586-025-08618-7 Pubmed: 40044849 ]

EMD-44247
Download Map
3D View
Biased agonist bound CB1-Gi structure
Release date: March 5, 2025
Resolution: 3.03 Å
EM Method: Single-particle
Fitted PDBs: 9b65
Q-score: 0.542

Rangari VA, O'Brien ES, Powers AS, Slivicki RA, Bertels Z, Appourchaux K, Aydin D, Ramos-Gonzalez N, Mwirigi J, Lin L, Mangutov E, Sobecks BL, Awad-Agbaria Y, Uphade MB, Aguilar J, Peddada TN, Shiimura Y, Huang XP, Folarin-Hines J, Payne M, Kalathil A, Varga BR, Kobilka BK, Pradhan AA, Cameron MD, Kumar KK, Dror RO, Gereau 4th RW, Majumdar S

Nature (2025) 640 pp. 265-273 [ DOI: doi:10.1038/s41586-025-08618-7 Pubmed: 40044849 ]

EMD-41783
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3D View
CDPPB bound inactive mGlu5, local refinement on TM region
Release date: Dec. 18, 2024
Resolution: 4.0 Å
EM Method: Single-particle

Krishna Kumar K, Wang H, Habrian C, Latorraca NR, Xu J, O'Brien ES, Zhang C, Montabana E, Koehl A, Marqusee S, Isacoff EY, Kobilka BK

Nature (2024) 629 pp. 951-956 [ Pubmed: 38632403 DOI: doi:10.1038/s41586-024-07327-x ]

EMD-41787
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3D View
CDPPB bound inactive mGlu5, non-uniform refinement of the whole complex
Release date: Dec. 18, 2024
Resolution: 3.3 Å
EM Method: Single-particle

Krishna Kumar K, Wang H, Habrian C, Latorraca NR, Xu J, O'Brien ES, Zhang C, Montabana E, Koehl A, Marqusee S, Isacoff EY, Kobilka BK

Nature (2024) 629 pp. 951-956 [ Pubmed: 38632403 DOI: doi:10.1038/s41586-024-07327-x ]

EMD-41789
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3D View
TM region local refinement of CDPPB, QUS bound mGlu5 in complex with Nb43
Release date: Dec. 18, 2024
Resolution: 4.46 Å
EM Method: Single-particle

Krishna Kumar K, Wang H, Habrian C, Latorraca NR, Xu J, O'Brien ES, Zhang C, Montabana E, Koehl A, Marqusee S, Isacoff EY, Kobilka BK

Nature (2024) 629 pp. 951-956 [ Pubmed: 38632403 DOI: doi:10.1038/s41586-024-07327-x ]

EMD-41793
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3D View
CDDPPB, QUS bound mGlu5 in complex with Nb43, local refinement on the VFT region
Release date: Dec. 18, 2024
Resolution: 2.89 Å
EM Method: Single-particle

Krishna Kumar K, Wang H, Habrian C, Latorraca NR, Xu J, O'Brien ES, Zhang C, Montabana E, Koehl A, Marqusee S, Isacoff EY, Kobilka BK

Nature (2024) 629 pp. 951-956 [ Pubmed: 38632403 DOI: doi:10.1038/s41586-024-07327-x ]

EMD-41796
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3D View
CDPPB, QUS bound mGlu5 in complex with Nb43, non uniform refinement of the whole complex
Release date: Dec. 18, 2024
Resolution: 2.93 Å
EM Method: Single-particle

Krishna Kumar K, Wang H, Kobilka BK

To Be Published

EMD-41803
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3D View
QUS bound active mGlu5 in complex with Nb43, non-uniform refinement on the whole complex
Release date: Dec. 18, 2024
Resolution: 2.93 Å
EM Method: Single-particle

Krishna Kumar K, Wang H, Kobilka BK

To Be Published

EMD-41804
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3D View
QUS bound active mGlu5 in complex with Nb43, local refinement on the TM region
Release date: Dec. 18, 2024
Resolution: 4.24 Å
EM Method: Single-particle

Krishna Kumar K, Wang H, Habrian C, Latorraca NR, Xu J, O'Brien ES, Zhang C, Montabana E, Koehl A, Marqusee S, Isacoff EY, Kobilka BK

Nature (2024) 629 pp. 951-956 [ Pubmed: 38632403 DOI: doi:10.1038/s41586-024-07327-x ]

Sort by: Download
Showing 1 - 10 of 237. Page 1 of 24
Display:
Statistics
×

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Preview first 10
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Filter By

Current Database

  • EMDB [229]
  • EMPIAR [8]

Current status

  • REL [237]

Sample type

  • Protein [219]
  • Complex [216]
  • Ligand [124]
  • Cellular component [13]

Organism

  • Homo sapiens [228]
  • Mus musculus [37]
  • Lama glama [19]
  • Synthetic construct [8]
  • Rattus norvegicus [5]
  • Human cytomegalovirus [4]
  • Bos taurus [3]
  • (no species) [2]
  • Human cytomegalovirus [1]
  • Epstein-barr virus (strain gd1) [1]
  • Oryctolagus cuniculus [1]

EM Method

  • Single-particle [229]

Resolution

  • ≥ 2Å and < 3Å [15]
  • ≥ 3Å and < 4Å [190]
  • ≥ 4Å and < 5Å [23]
  • ≥ 6Å and < 8Å [1]

Model molecular weight

  • 50-100 kDa [26]
  • 100-250 kDa [112]
  • 250-500 kDa [1]

Release Date

  • 2025 [3]
  • 2024 [177]
  • 2023 [12]
  • 2022 [18]
  • 2021 [6]
  • 2020 [8]
  • 2019 [9]
  • 2018 [2]
  • 2017 [2]

Author by name

  • Kobilka BK [230]
  • Skiniotis G [199]
  • Hilger D [171]
  • Seven AB [171]
  • Gmeiner P [169]
  • Papasergi-scott MM [169]
  • Panova O [166]
  • Gao Y [164]
  • Eskici G [162]
  • Hildebrand PW [162]
  • Casiraghi M [161]
  • Maul L [161]
  • Batebi H [160]
  • He F [160]
  • Perez-hernandez G [160]
  • Wang H [29]
  • Krishna Kumar K [22]
  • Xu J [22]
  • Qu Q [20]
  • Latorraca NR [17]
  • Maeda S [17]
  • Koehl A [16]
  • O Brien Es [16]
  • Zhang C [15]
  • Dror RO [14]
  • Robertson MJ [14]
  • Isacoff EY [13]
  • Habrian C [12]
  • Marqusee S [12]
  • Montabana E [12]
  • Inoue A [11]
  • Feng D [10]
  • Hu H [10]
  • Sun B [10]
  • Kato HE [9]
  • Kobilka TS [9]
  • Mathiesen JM [9]
  • Suomivuori CM [9]
  • Zhang Y [9]
  • Huang W [8]
  • Du Y [7]
  • Hubner H [7]
  • Majumdar S [7]
  • Barros-alvarez X [6]
  • Garcia KC [6]
  • Showalter AD [6]
  • Sloop KW [6]
  • Tsutsumi N [6]
  • Waghray D [6]
  • Weis WI [6]
  • Willard FS [6]
  • Appourchaux K [5]
  • Bueno AB [5]
  • Che T [5]
  • Chen Q [5]
  • Coghlan MP [5]
  • Fonseca R [5]
  • Ho JD [5]
  • Jude KM [5]
  • Stutsman C [5]
  • Sun X [5]
  • Velasco A [5]
  • Vieth M [5]
  • Voegele M [5]
  • Zhang L [5]
  • Zhao J [5]
  • Aihara E [4]
  • Alsina-fernandez J [4]
  • Aydin D [4]
  • Brown RA [4]
  • Cameron MD [4]
  • Carpenter JW [4]
  • Chu M [4]
  • Diberto JF [4]
  • Ding L [4]
  • Dunbar JD [4]
  • Emmerson PJ [4]
  • Hu Y [4]
  • Jin C [4]
  • Kaindl J [4]
  • Mohammed FA [4]
  • Moyers JS [4]
  • Niu X [4]
  • Paggi JM [4]
  • Roth BL [4]
  • Suter TM [4]
  • Tao Y [4]
  • Tarrasch J [4]
  • Varga BR [4]
  • Wang Q [4]
  • Cao S [3]
  • Chen G [3]
  • Deupi X [3]
  • Dutta S [3]
  • Eans SO [3]
  • El Daibani A [3]
  • Heng J [3]
  • Kong F [3]
  • Kumar KK [3]
  • Laermans T [3]

Author by ORCID

  • Kobilka BK [218]
  • Skiniotis G [185]
  • Gmeiner P [169]
  • Hilger D [166]
  • Papasergi-scott MM [165]
  • Gao Y [163]
  • Batebi H [160]
  • Panova O [160]
  • He F [160]
  • Perez-hernandez G [160]
  • Hildebrand PW [160]
  • Xu J [17]
  • O'brien ES [16]
  • Latorraca NR [16]
  • Maeda S [12]
  • Krishna Kumar K [12]
  • Marqusee S [11]
  • Isacoff EY [11]
  • Robertson MJ [10]
  • Zhang Y [9]
  • Du Y [7]
  • Majumdar S [7]
  • Inoue A [7]
  • Mathiesen JM [7]
  • Sloop KW [6]
  • Garcia KC [6]
  • Tsutsumi N [6]
  • Qu Q [6]
  • Dror RO [6]
  • Sun B [5]
  • Appourchaux K [5]
  • Zhao J [5]
  • Coghlan MP [5]
  • Che T [5]
  • Hubner H [5]
  • Fonseca R [5]
  • Chen Q [5]
  • Hu Y [4]
  • Roth BL [4]
  • Jin C [4]
  • Kato HE [4]
  • Suomivuori CM [4]
  • Aydin D [4]
  • Bueno AB [4]
  • Mohammed FA [4]
  • Diberto JF [4]
  • Tao Y [4]
  • Brown RA [4]
  • Moyers JS [4]
  • Barros-alvarez X [3]
  • Wang N [3]
  • Meyerowitz JG [3]
  • Kong F [3]
  • Yan C [3]
  • Mclaughlin JP [3]
  • Toyoda Y [3]
  • Zhu A [3]
  • Dutta S [3]
  • Steyaert J [3]
  • Weis WI [3]
  • Huang W [3]
  • Rangari VA [3]
  • Kumar KK [3]
  • Liu X [3]
  • Deupi X [3]
  • Scheerer P [2]
  • Paisdzior S [2]
  • Mielke T [2]
  • Wang HW [2]
  • Pradhan AA [2]
  • Madasu MK [2]
  • Biebermann H [2]
  • Huang XP [2]
  • Slivicki RA [2]
  • Willard FS [2]
  • Burger J [2]
  • Peddada TN [2]
  • Mwirigi J [2]
  • Gereau 4Th Rw [2]
  • Schacherl M [2]
  • Schertler GFX [2]
  • Hilal T [2]
  • Kwiatkowski D [2]
  • Awad-agbaria Y [2]
  • Heyder NA [2]
  • Al-hasani R [2]
  • Faouzi A [2]
  • Ramos-gonzalez N [2]
  • Kuhnen P [2]
  • Schmidt A [2]
  • Dawson R [2]
  • Cameron MD [2]
  • Katritch V [2]
  • Beck-sickinger AG [2]
  • Speck D [2]
  • Brennan PC [1]
  • Nucci N [1]
  • Furness SGB [1]
  • Sexton PM [1]
  • Coudrat T [1]

Journal

  • NATURE [196]
  • PNAS [8]
  • NAT COMMUN [7]
  • SCI ADV [6]
  • NAT CHEM BIOL [5]
  • BIORXIV [4]
  • CELL [3]
  • SCIENCE [3]
  • ANGEW CHEM INT ED ENGL [2]
  • CELL REP [2]
  • CELL RES [2]
  • TO BE PUBLISHED [2]
  • IMMUNITY [1]

Software

  • CRYOSPARC [168]
  • RELION [19]
  • FREALIGN [2]
  • CISTEM [1]

Microscope

  • FEI TITAN KRIOS [221]
  • TFS KRIOS [8]

Electron Source

  • FIELD EMISSION GUN [229]

Film or detector model

  • GATAN K3 6K X 4K [155]
  • GATAN K2 SUMMIT 4K X 4K [43]
  • GATAN K3 BIOQUANTUM 6K X 4K [21]
  • GATAN K2 QUANTUM 4K X 4K [5]
  • FEI FALCON IV 4K X 4K [3]
  • FEI FALCON III 4K X 4K [2]

EMPIAR Experiment type

  • EMDB [8]

EMPIAR Image category

  • MICROGRAPHS - MULTIFRAME [8]

External links

  • AlphaFold DB [219]
  • PDBe-Kb [219]
  • UniProt [219]
  • EMPIAR [164]
  • Gene Ontology [139]
  • InterPro [139]
  • PDB [139]
  • Pfam [139]
  • ChEMBL [86]
  • ChEBI [82]
  • DrugBank [78]
  • EMDB [8]
  • CATH [5]
  • SCOP2 [4]