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PRION

Filter By

Current Database

  • EMDB [93]
  • EMPIAR [1]

Current status

  • REL [94]

Sample type

  • Protein [83]
  • Complex [54]
  • Ligand [27]
  • Sample [20]
  • Cellular component [11]
  • Virus [8]
  • Tissue [3]
  • Cell [2]
  • Other [1]
  • RNA [1]

Organism

  • Homo sapiens [25]
  • Synthetic construct [20]
  • Saccharomyces cerevisiae [14]
  • Mus musculus [12]
  • Bacillus phage phi29 [7]
  • Mesocricetus auratus [3]
  • Human immunodeficiency virus 1 [3]
  • Pseudomonas aeruginosa [2]
  • Odocoileus virginianus [2]
  • African swine fever virus [1]
  • Myodes glareolus [1]
  • Podospora anserina [1]
  • Hiv whole-genome vector aa1305#18 [1]
  • Drosophila melanogaster [1]
  • Escherichia coli [1]
  • Ovis aries [1]

EM Method

  • Helical reconstruction [43]
  • Electron Crystallography [24]
  • Single-particle [19]
  • Tomography [5]
  • Subtomogram averaging [2]

Resolution

  • < 2Å [19]
  • ≥ 2Å and < 3Å [14]
  • ≥ 3Å and < 4Å [27]
  • ≥ 4Å and < 5Å [3]
  • ≥ 5Å and < 6Å [1]
  • ≥ 6Å and < 8Å [3]
  • ≥ 8Å and < 12Å [4]
  • ≥ 12Å and < 16Å [3]
  • ≥ 16Å and < 20Å [1]
  • ≥ 20Å and < 30Å [5]

Model molecular weight

  • 0-50 kDa [1]
  • 100-250 kDa [2]
  • 2-5 MDa [1]

Release Date

  • 2026 [1]
  • 2025 [4]
  • 2024 [6]
  • 2023 [4]
  • 2022 [14]
  • 2021 [9]
  • 2020 [3]
  • 2019 [8]
  • 2018 [20]
  • 2016 [5]
  • 2015 [5]
  • 2014 [4]
  • 2013 [1]
  • 2012 [2]
  • 2010 [1]
  • 2009 [5]
  • 2006 [2]

Author by name

  • Rodriguez JA [26]
  • Gonen T [24]
  • Hattne J [22]
  • Shi D [22]
  • Gallagher-jones M [21]
  • Glynn C [21]
  • Martynowycz MW [20]
  • Zee CT [20]
  • Saibil HR [13]
  • Fandrich M [9]
  • Schmidt M [9]
  • Sawaya MR [8]
  • Collinge J [7]
  • Eisenberg DS [7]
  • Gui M [7]
  • Saibil H [7]
  • Wang D [7]
  • Xiang Y [7]
  • Xu J [7]
  • Cascio D [6]
  • Lindquist S [6]
  • Artikis E [5]
  • Caughey B [5]
  • Clare DK [5]
  • Fernandez A [5]
  • Garringer HJ [5]
  • Ghetti B [5]
  • Hallinan GI [5]
  • Hoq MR [5]
  • Hoyt F [5]
  • Hughson AG [5]
  • Jiang W [5]
  • Race B [5]
  • Schwartz CL [5]
  • Shorter J [5]
  • Vago FS [5]
  • Vidal R [5]
  • Bansal A [4]
  • Biedermann A [4]
  • Collazo MJ [4]
  • Haupt C [4]
  • Joiner S [4]
  • Li D [4]
  • Plisson C [4]
  • Puscalau-girtu I [4]
  • Rennegarbe M [4]
  • Reyes FE [4]
  • Rodriguez J [4]
  • Snead D [4]
  • Wadsworth JDF [4]
  • Wenborn A [4]
  • Wendler P [4]
  • Alam P [3]
  • Annamalai AS [3]
  • Asturias F [3]
  • Baron GS [3]
  • Bester S [3]
  • Betts J [3]
  • Borkowski B [3]
  • Boyer DR [3]
  • Briganti L [3]
  • Chen ZJ [3]
  • Clare D [3]
  • Courouble VV [3]
  • Engelman AN [3]
  • Faendrich M [3]
  • Francis AC [3]
  • Ghosh M [3]
  • Griffin PR [3]
  • Haney R [3]
  • He X [3]
  • Heerde T [3]
  • Hou F [3]
  • Huang LJ [3]
  • Huang SW [3]
  • Hudait A [3]
  • Iqbal N [3]
  • Jiang Q-X [3]
  • Jiang QX [3]
  • Kewalramani VN [3]
  • Kraus A [3]
  • Kvaratskhelia M [3]
  • Liberta F [3]
  • Manka SW [3]
  • Melikyan GB [3]
  • O Driscoll J [3]
  • Raymond GJ [3]
  • Shkriabai N [3]
  • Singh PK [3]
  • Stecher S [3]
  • Tattum MH [3]
  • Voth GA [3]
  • Wei G [3]
  • Xu H [3]
  • Yu Z [3]
  • Zhang W [3]
  • Zhang X [3]
  • Zheng H [3]
  • De La Cruz Mj [3]
  • Barbian K [2]

Author by ORCID

  • Schwartz CL [2]
  • Baron T [1]
  • Retailleau A [1]
  • Johansson MJO [1]
  • Loquet A [1]
  • Lewis AJ [1]
  • Ichas F [1]
  • Kraus A [1]
  • Van Den Heuvel L [1]
  • Bezard E [1]
  • Bousset L [1]
  • Laferriere F [1]
  • Turnbull K [1]
  • Stahlberg H [1]
  • Caughey B [1]
  • Burger D [1]
  • Atkinson GC [1]
  • Poujol C [1]
  • Nissan T [1]
  • Meissner WG [1]
  • Hauryliuk V [1]
  • Zhou Y [1]
  • Novacek J [1]
  • De La Seigliere H [1]

Journal

  • NAT COMMUN [21]
  • STRUCTURE [20]
  • PNAS [10]
  • ACTA NEUROPATHOL [7]
  • MOL CELL [6]
  • NAT STRUCT MOL BIOL [6]
  • J MOL BIOL [4]
  • TO BE PUBLISHED [4]
  • ELIFE [3]
  • J CELL BIOL [3]
  • BIORXIV [2]
  • BIOMEDICINES [1]
  • CELL MOL IMMUNOL [1]
  • J AM CHEM SOC [1]
  • NAT CHEM BIOL [1]
  • NATURE [1]
  • NUCLEIC ACIDS RES [1]
  • OPEN BIOL [1]
  • PLOS PATHOG [1]
  • SCI ADV [1]
  • SCI REP [1]
  • SCIENCE [1]

Software

  • RELION [30]
  • CTFFIND [5]
  • SPIDER [5]
  • IMAGIC SPIDER MRC [4]
  • IMOD [4]
  • SCALEPACK [4]
  • SHELXD [4]
  • CHIMERA [3]
  • SPIDER, MRC, EMAN, IMAGIC4D [2]
  • CHIMERA, SITUS [1]
  • CRYOSPARC [1]
  • GCTF [1]
  • RELION, IHRSR [1]
  • SPIDER, EMAN, IHRSR, BSOFT [1]

Microscope

  • FEI TITAN KRIOS [31]
  • FEI TECNAI F20 [27]
  • TFS KRIOS [11]
  • FEI POLARA 300 [5]
  • FEI TALOS ARCTICA [4]
  • FEI TECNAI F30 [3]
  • FEI TECNAI 10 [2]
  • FEI TECNAI 12 [2]
  • JEOL 1230 [2]
  • JEOL 2200FS [2]
  • JEOL CRYO ARM 300 [2]
  • FEI TECNAI 20 [1]
  • FEI/PHILIPS CM200FEG [1]

Electron Source

  • FIELD EMISSION GUN [87]
  • TUNGSTEN HAIRPIN [6]

Film or detector model

  • TVIPS TEMCAM-F416 4K X 4K [26]
  • KODAK SO-163 FILM [14]
  • GATAN K2 SUMMIT 4K X 4K [13]
  • GATAN K3 6K X 4K [13]
  • GATAN K3 BIOQUANTUM 6K X 4K [9]
  • FEI FALCON II 4K X 4K [6]
  • GATAN MULTISCAN [4]
  • FEI FALCON III 4K X 4K [2]
  • GATAN K3 BIOCONTINUUM 6K X 4K [2]
  • FEI FALCON IV 4K X 4K [1]
  • GATAN K2 QUANTUM 4K X 4K [1]

EMPIAR Experiment type

  • EMDB [1]

EMPIAR Image category

  • MICROGRAPHS - SINGLE FRAME [1]

External links

  • AlphaFold DB [4]
  • PDB [4]
  • PDBe-Kb [4]
  • UniProt [4]
  • Gene Ontology [3]
  • InterPro [3]
  • Pfam [2]
  • ChEBI [1]
  • ChEMBL [1]
  • Complex Portal [1]
  • DrugBank [1]
  • EMDB [1]
  • EMPIAR [1]
Sort by: Download
Showing 1 - 10 of 94. Page 1 of 10
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EMD-75514
Download Map
3D View
Structure of amplified aSyn filament by using seed amplification assay SAA from MSA patient CSF.
Release date: Feb. 25, 2026
Resolution: 3.18 Å
EM Method: Helical reconstruction
Fitted PDBs: 10xu
Q-score: 0.524

Wang F, Banerjee V, Barria C, Ramirez S, Allison T, Gorski D, Evans H, Nguyen Q, Harrison D, Al-Lahham R, De Gregorio Carbonell N, Pinho M, Kaalund S, Folke J, Aznar S, Concha-Marambio L, Ishtikhar M, Mallampalli VK, Pritzkow S, Shahnawaz M, Baker ML, Serysheva I, Soto C

Nat Commun (2025) 16 pp. 11266-11266 [ Pubmed: 41372188 DOI: doi:10.1038/s41467-025-66146-4 ]

EMD-60945
Download Map
3D View
Structure of apo AsfvPrimPol with dodecamer
CryoEM
Release date: Dec. 24, 2025
Resolution: 3.7 Å
EM Method: Single-particle
Fitted PDBs: 9iwa

Xu KE, Chen YT

To Be Published

EMD-62570
Download Map
3D View
Cryo-EM structure of the TIA-1 prion-like domain amyloid fibril, WT
CryoEM
Release date: Dec. 3, 2025
Resolution: 3.36 Å
EM Method: Helical reconstruction
Fitted PDBs: 9kty
Q-score: 0.507

Inaoka D, Miyata T, Makino F, Ohtani Y, Ekari M, Kobayashi R, Imamura K, Sakamoto E, Kodama ST, Yoshida N, Kato T, Namba K, Tochio H, Sekiyama N

To Be Published

EMD-62571
Download Map
3D View
Cryo-EM structure of the TIA-1 prion-like domain amyloid fibril, G355R
CryoEM
Release date: Dec. 3, 2025
Resolution: 3.1 Å
EM Method: Helical reconstruction
Fitted PDBs: 9ktz
Q-score: 0.485

Inaoka D, Miyata T, Makino F, Ohtani Y, Ekari M, Kobayashi R, Imamura K, Sakamoto E, Kodama ST, Yoshida N, Kato T, Namba K, Tochio H, Sekiyama N

To Be Published

EMD-54402
Download Map
3D View
Raw data
EMPIAR-12890
Structure of in-vivo formed alpha-synuclein fibrils purified from a M83 /- mouse brain injected with recombinant 1B fibrils
CryoEM
Release date: July 30, 2025
Resolution: 3.8 Å
EM Method: Helical reconstruction
Fitted PDBs: 9rzf
Q-score: 0.511

Burger D, Kashyrina M, van den Heuvel L, de La Seigliere H, Lewis AJ, De Nuccio F, Mohammed I, Verchere J, Feuillie C, Berbon M, Arotcarena ML, Retailleau A, Bezard E, Canron MH, Meissner WG, Loquet A, Bousset L, Poujol C, Nilsson KPR, Laferriere F, Baron T, Lofrumento DD, De Giorgi F, Stahlberg H, Ichas F

Nature (2025) 648 pp. 409-417 [ Pubmed: 41193804 DOI: doi:10.1038/s41586-025-09698-1 ]

EMD-42886
Download Map
3D View
Cryo-EM structure of tau filaments made from jR2R3-P301L peptides induced with heparin
CryoEM
Release date: Dec. 11, 2024
Resolution: 3.0 Å
EM Method: Helical reconstruction
Fitted PDBs: 8v1n
Q-score: 0.516

Vigers MP, Lobo S, Najafi S, Dubose A, Tsay K, Ganguly P, Longhini AP, Jin Y, Buratto SK, Kosik KS, Shell MS, Shea JE, Han S

PNAS (2025) 122 pp. e2421391122-e2421391122 [ Pubmed: 40294272 DOI: doi:10.1073/pnas.2421391122 ]

EMD-47020
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3D View
Chronic wasting disease prion fibril
CryoEM
Release date: Nov. 6, 2024
Resolution: 2.8 Å
EM Method: Helical reconstruction
Fitted PDBs: 9dmy
Q-score: 0.607

Alam P, Hoyt F, Artikis E, Soukup J, Hughson AG, Schwartz CL, Barbian K, Miller MW, Race B, Caughey B

Acta Neuropathol (2024) 148 pp. 56-56 [ Pubmed: 39448454 DOI: doi:10.1007/s00401-024-02813-y ]

EMD-47021
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3D View
Glycosylated chronic wasting disease prion fibril
CryoEM
Release date: Nov. 6, 2024
Resolution: 2.8 Å
EM Method: Helical reconstruction
Fitted PDBs: 9dmz
Q-score: 0.592

Alam P, Hoyt F, Artikis E, Soukup J, Hughson AG, Schwartz CL, Barbian K, Miller MW, Race B, Caughey B

Acta Neuropathol (2024) 148 pp. 56-56 [ Pubmed: 39448454 DOI: doi:10.1007/s00401-024-02813-y ]

EMD-35019
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3D View
MAVS fibrils surrounding the mitochondria
CryoEM
Release date: July 10, 2024
EM Method: Tomography

Yu X, Wang P, Zhou N, Zhang L, Gong X, Guo Q, Jiang Z

Cell Mol Immunol (2026) [ DOI: doi:10.1038/s41423-025-01382-8 Pubmed: 41495444 ]

EMD-40677
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3D View
Structural insights into cellular control of the human CPEB3 prion, functionally regulated by a labile-amyloid-forming segment
CryoEM
Release date: May 8, 2024
Resolution: 3.0 Å
EM Method: Helical reconstruction
Fitted PDBs: 8spa
Q-score: 0.527

Flores MD, Sawaya MR, Boyer DR, Zink S, Fioriti L, Rodriguez JA

To Be Published

Sort by: Download
Showing 1 - 10 of 94. Page 1 of 10
Display:
Statistics
×

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Preview first 10
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Filter By

Current Database

  • EMDB [93]
  • EMPIAR [1]

Current status

  • REL [94]

Sample type

  • Protein [83]
  • Complex [54]
  • Ligand [27]
  • Sample [20]
  • Cellular component [11]
  • Virus [8]
  • Tissue [3]
  • Cell [2]
  • Other [1]
  • RNA [1]

Organism

  • Homo sapiens [25]
  • Synthetic construct [20]
  • Saccharomyces cerevisiae [14]
  • Mus musculus [12]
  • Bacillus phage phi29 [7]
  • Mesocricetus auratus [3]
  • Human immunodeficiency virus 1 [3]
  • Pseudomonas aeruginosa [2]
  • Odocoileus virginianus [2]
  • African swine fever virus [1]
  • Myodes glareolus [1]
  • Podospora anserina [1]
  • Hiv whole-genome vector aa1305#18 [1]
  • Drosophila melanogaster [1]
  • Escherichia coli [1]
  • Ovis aries [1]

EM Method

  • Helical reconstruction [43]
  • Electron Crystallography [24]
  • Single-particle [19]
  • Tomography [5]
  • Subtomogram averaging [2]

Resolution

  • < 2Å [19]
  • ≥ 2Å and < 3Å [14]
  • ≥ 3Å and < 4Å [27]
  • ≥ 4Å and < 5Å [3]
  • ≥ 5Å and < 6Å [1]
  • ≥ 6Å and < 8Å [3]
  • ≥ 8Å and < 12Å [4]
  • ≥ 12Å and < 16Å [3]
  • ≥ 16Å and < 20Å [1]
  • ≥ 20Å and < 30Å [5]

Model molecular weight

  • 0-50 kDa [1]
  • 100-250 kDa [2]
  • 2-5 MDa [1]

Release Date

  • 2026 [1]
  • 2025 [4]
  • 2024 [6]
  • 2023 [4]
  • 2022 [14]
  • 2021 [9]
  • 2020 [3]
  • 2019 [8]
  • 2018 [20]
  • 2016 [5]
  • 2015 [5]
  • 2014 [4]
  • 2013 [1]
  • 2012 [2]
  • 2010 [1]
  • 2009 [5]
  • 2006 [2]

Author by name

  • Rodriguez JA [26]
  • Gonen T [24]
  • Hattne J [22]
  • Shi D [22]
  • Gallagher-jones M [21]
  • Glynn C [21]
  • Martynowycz MW [20]
  • Zee CT [20]
  • Saibil HR [13]
  • Fandrich M [9]
  • Schmidt M [9]
  • Sawaya MR [8]
  • Collinge J [7]
  • Eisenberg DS [7]
  • Gui M [7]
  • Saibil H [7]
  • Wang D [7]
  • Xiang Y [7]
  • Xu J [7]
  • Cascio D [6]
  • Lindquist S [6]
  • Artikis E [5]
  • Caughey B [5]
  • Clare DK [5]
  • Fernandez A [5]
  • Garringer HJ [5]
  • Ghetti B [5]
  • Hallinan GI [5]
  • Hoq MR [5]
  • Hoyt F [5]
  • Hughson AG [5]
  • Jiang W [5]
  • Race B [5]
  • Schwartz CL [5]
  • Shorter J [5]
  • Vago FS [5]
  • Vidal R [5]
  • Bansal A [4]
  • Biedermann A [4]
  • Collazo MJ [4]
  • Haupt C [4]
  • Joiner S [4]
  • Li D [4]
  • Plisson C [4]
  • Puscalau-girtu I [4]
  • Rennegarbe M [4]
  • Reyes FE [4]
  • Rodriguez J [4]
  • Snead D [4]
  • Wadsworth JDF [4]
  • Wenborn A [4]
  • Wendler P [4]
  • Alam P [3]
  • Annamalai AS [3]
  • Asturias F [3]
  • Baron GS [3]
  • Bester S [3]
  • Betts J [3]
  • Borkowski B [3]
  • Boyer DR [3]
  • Briganti L [3]
  • Chen ZJ [3]
  • Clare D [3]
  • Courouble VV [3]
  • Engelman AN [3]
  • Faendrich M [3]
  • Francis AC [3]
  • Ghosh M [3]
  • Griffin PR [3]
  • Haney R [3]
  • He X [3]
  • Heerde T [3]
  • Hou F [3]
  • Huang LJ [3]
  • Huang SW [3]
  • Hudait A [3]
  • Iqbal N [3]
  • Jiang Q-X [3]
  • Jiang QX [3]
  • Kewalramani VN [3]
  • Kraus A [3]
  • Kvaratskhelia M [3]
  • Liberta F [3]
  • Manka SW [3]
  • Melikyan GB [3]
  • O Driscoll J [3]
  • Raymond GJ [3]
  • Shkriabai N [3]
  • Singh PK [3]
  • Stecher S [3]
  • Tattum MH [3]
  • Voth GA [3]
  • Wei G [3]
  • Xu H [3]
  • Yu Z [3]
  • Zhang W [3]
  • Zhang X [3]
  • Zheng H [3]
  • De La Cruz Mj [3]
  • Barbian K [2]

Author by ORCID

  • Schwartz CL [2]
  • Baron T [1]
  • Retailleau A [1]
  • Johansson MJO [1]
  • Loquet A [1]
  • Lewis AJ [1]
  • Ichas F [1]
  • Kraus A [1]
  • Van Den Heuvel L [1]
  • Bezard E [1]
  • Bousset L [1]
  • Laferriere F [1]
  • Turnbull K [1]
  • Stahlberg H [1]
  • Caughey B [1]
  • Burger D [1]
  • Atkinson GC [1]
  • Poujol C [1]
  • Nissan T [1]
  • Meissner WG [1]
  • Hauryliuk V [1]
  • Zhou Y [1]
  • Novacek J [1]
  • De La Seigliere H [1]

Journal

  • NAT COMMUN [21]
  • STRUCTURE [20]
  • PNAS [10]
  • ACTA NEUROPATHOL [7]
  • MOL CELL [6]
  • NAT STRUCT MOL BIOL [6]
  • J MOL BIOL [4]
  • TO BE PUBLISHED [4]
  • ELIFE [3]
  • J CELL BIOL [3]
  • BIORXIV [2]
  • BIOMEDICINES [1]
  • CELL MOL IMMUNOL [1]
  • J AM CHEM SOC [1]
  • NAT CHEM BIOL [1]
  • NATURE [1]
  • NUCLEIC ACIDS RES [1]
  • OPEN BIOL [1]
  • PLOS PATHOG [1]
  • SCI ADV [1]
  • SCI REP [1]
  • SCIENCE [1]

Software

  • RELION [30]
  • CTFFIND [5]
  • SPIDER [5]
  • IMAGIC SPIDER MRC [4]
  • IMOD [4]
  • SCALEPACK [4]
  • SHELXD [4]
  • CHIMERA [3]
  • SPIDER, MRC, EMAN, IMAGIC4D [2]
  • CHIMERA, SITUS [1]
  • CRYOSPARC [1]
  • GCTF [1]
  • RELION, IHRSR [1]
  • SPIDER, EMAN, IHRSR, BSOFT [1]

Microscope

  • FEI TITAN KRIOS [31]
  • FEI TECNAI F20 [27]
  • TFS KRIOS [11]
  • FEI POLARA 300 [5]
  • FEI TALOS ARCTICA [4]
  • FEI TECNAI F30 [3]
  • FEI TECNAI 10 [2]
  • FEI TECNAI 12 [2]
  • JEOL 1230 [2]
  • JEOL 2200FS [2]
  • JEOL CRYO ARM 300 [2]
  • FEI TECNAI 20 [1]
  • FEI/PHILIPS CM200FEG [1]

Electron Source

  • FIELD EMISSION GUN [87]
  • TUNGSTEN HAIRPIN [6]

Film or detector model

  • TVIPS TEMCAM-F416 4K X 4K [26]
  • KODAK SO-163 FILM [14]
  • GATAN K2 SUMMIT 4K X 4K [13]
  • GATAN K3 6K X 4K [13]
  • GATAN K3 BIOQUANTUM 6K X 4K [9]
  • FEI FALCON II 4K X 4K [6]
  • GATAN MULTISCAN [4]
  • FEI FALCON III 4K X 4K [2]
  • GATAN K3 BIOCONTINUUM 6K X 4K [2]
  • FEI FALCON IV 4K X 4K [1]
  • GATAN K2 QUANTUM 4K X 4K [1]

EMPIAR Experiment type

  • EMDB [1]

EMPIAR Image category

  • MICROGRAPHS - SINGLE FRAME [1]

External links

  • AlphaFold DB [4]
  • PDB [4]
  • PDBe-Kb [4]
  • UniProt [4]
  • Gene Ontology [3]
  • InterPro [3]
  • Pfam [2]
  • ChEBI [1]
  • ChEMBL [1]
  • Complex Portal [1]
  • DrugBank [1]
  • EMDB [1]
  • EMPIAR [1]