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EMD-42886

Helical reconstruction
3.0 Å
EMD-42886
3D View Gallery
Deposition: 20/11/2023
Map released: 11/12/2024
Last modified: 25/06/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-42886
Download
3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 8v1n summary report (pdf.gz) Map and 8v1n FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM structure of tau filaments made from jR2R3-P301L peptides induced with heparin

EMD-42886

Helical reconstruction
3.0 Å
EMD-42886
3D View Gallery
Deposition: 20/11/2023
Map released: 11/12/2024
Last modified: 25/06/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Filament of tau jR2R3-P301L peptide indued with heparin
Fitted models: 8v1n

Deposition Authors: Vigers M, Han S
Water-directed pinning is key to tau prion formation.
Vigers MP , Lobo S , Najafi S, Dubose A , Tsay K, Ganguly P , Longhini AP, Jin Y , Buratto SK, Kosik KS, Shell MS, Shea JE, Han S
(2025) PNAS , 122 , e2421391122 - e2421391122
PUBMED: 40294272
DOI: doi:10.1073/pnas.2421391122
ISSN: 1091-6490
ASTM: PNASA6