EMD-42886

Helical reconstruction
3.0 Å
EMD-42886
3D View Gallery
Deposition: 20/11/2023
Map released: 11/12/2024
Last modified: 25/06/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-42886

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-8v1n summary report (pdf.gz) Map-8v1n FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM structure of tau filaments made from jR2R3-P301L peptides induced with heparin

EMD-42886

Helical reconstruction
3.0 Å
EMD-42886
3D View Gallery
Deposition: 20/11/2023
Map released: 11/12/2024
Last modified: 25/06/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Filament of tau jR2R3-P301L peptide indued with heparin
Fitted models: 8v1n

Deposition Authors: Vigers M, Han S
Water-directed pinning is key to tau prion formation.
Vigers MP , Lobo S , Najafi S, Dubose A , Tsay K, Ganguly P , Longhini AP, Jin Y , Buratto SK, Kosik KS, Shell MS, Shea JE, Han S
(2025) PNAS , 122 , e2421391122 - e2421391122
PUBMED: 40294272
DOI: doi:10.1073/pnas.2421391122
ISSN: 1091-6490
ASTM: PNASA6