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CHEBI:35664 - EC 1.1.1.34/EC 1.1.1.88 (hydroxymethylglutaryl-CoA reductase) inhibitor

ChEBI IDCHEBI:35664
ChEBI NameEC 1.1.1.34/EC 1.1.1.88 (hydroxymethylglutaryl-CoA reductase) inhibitor
Stars
DefinitionAny EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD+ or NADP+ acceptor) inhibitor that inhibits HMG-CoA reductases. Hydroxymethylglutaryl-CoA reductase inhibitors have been shown to lower directly cholesterol synthesis. The Enzyme Commission designation is EC 1.1.1.34 for the NADPH-dependent enzyme and EC 1.1.1.88 for an NADH-dependent enzyme.
Last Modified11 June 2021
SubmitterMarcus Ennis
Wikipedia
ChEBI Ontology
Synonyms  Source
hydroxymethylglutaryl-CoA reductase inhibitorsChEBI
HMG-CoA reductase inhibitorChEBI
hydroxymethylglutaryl-CoA reductase inhibitorChEBI
HMG-CoA reductase inhibitorsChEBI
Manual XrefsDatabases
HMG-CoA_reductaseWikipedia
Citations