Assemblies
Multimeric state:
hetero tetramer
Accessible surface area:
40677.2 Å2
Buried surface area:
18693.02 Å2
Dissociation area:
2,842.79
Å2
Dissociation energy (ΔGdiss):
13.56
kcal/mol
Dissociation entropy (TΔSdiss):
14.99
kcal/mol
Symmetry number:
1
PDBe Complex ID:
PDB-CPX-107594
Macromolecules
Chain: A
Length: 622 amino acids
Theoretical weight: 68.31 KDa
Source organism: Sus scrofa
UniProt:
Pfam:
InterPro:
Length: 622 amino acids
Theoretical weight: 68.31 KDa
Source organism: Sus scrofa
UniProt:
- Canonical:
Q0QF01 (Residues: 43-664; Coverage: 94%)
Pfam:
InterPro:
- FAD-dependent oxidoreductase SdhA/FrdA/AprA
- FAD/NAD(P)-binding domain superfamily
- Succinate dehydrogenase, flavoprotein subunit
- FAD-dependent oxidoreductase 2, FAD binding domain
- Succinate dehydrogenase/fumarate reductase, flavoprotein subunit
- Fumarate reductase/succinate dehydrogenase, FAD-binding site
- Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily
- Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily
- Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal
![Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial in PDB entry 3ae8, assembly 1, front view.](https://www.ebi.ac.uk/pdbe/static/entry/3ae8_entity_1_front_image-200x200.png "Hetero tetrameric assembly 1 of PDB entry <span class='highlight'>3ae8</span> contains 1 copy of <span class='highlight'>Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial</span>. Front view.")
![Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial in PDB entry 3ae8, assembly 1, side view.](https://www.ebi.ac.uk/pdbe/static/entry/3ae8_entity_1_side_image-200x200.png "Hetero tetrameric assembly 1 of PDB entry <span class='highlight'>3ae8</span> contains 1 copy of <span class='highlight'>Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial</span>. Side view.")
![Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial in PDB entry 3ae8, assembly 1, top view.](https://www.ebi.ac.uk/pdbe/static/entry/3ae8_entity_1_top_image-200x200.png "Hetero tetrameric assembly 1 of PDB entry <span class='highlight'>3ae8</span> contains 1 copy of <span class='highlight'>Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial</span>. Top view.")
Chain: B
Length: 252 amino acids
Theoretical weight: 28.76 KDa
Source organism: Sus scrofa
UniProt:
Pfam:
InterPro:
Length: 252 amino acids
Theoretical weight: 28.76 KDa
Source organism: Sus scrofa
UniProt:
- Canonical: Q007T0 (Residues: 29-280; Coverage: 90%)
Pfam:
InterPro:
- Beta-grasp domain superfamily
- 2Fe-2S ferredoxin-like superfamily
- 2Fe-2S ferredoxin-type iron-sulfur binding domain
- Succinate dehydogenase/fumarate reductase N-terminal
- Succinate dehydrogenase/fumarate reductase iron-sulphur protein
- 2Fe-2S ferredoxin, iron-sulphur binding site
- Alpha-helical ferredoxin
- 4Fe-4S ferredoxin-type, iron-sulphur binding domain
- 4Fe-4S ferredoxin, iron-sulphur binding, conserved site
![Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial in PDB entry 3ae8, assembly 1, front view.](https://www.ebi.ac.uk/pdbe/static/entry/3ae8_entity_2_front_image-200x200.png "Hetero tetrameric assembly 1 of PDB entry <span class='highlight'>3ae8</span> contains 1 copy of <span class='highlight'>Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial</span>. Front view.")
![Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial in PDB entry 3ae8, assembly 1, side view.](https://www.ebi.ac.uk/pdbe/static/entry/3ae8_entity_2_side_image-200x200.png "Hetero tetrameric assembly 1 of PDB entry <span class='highlight'>3ae8</span> contains 1 copy of <span class='highlight'>Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial</span>. Side view.")
![Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial in PDB entry 3ae8, assembly 1, top view.](https://www.ebi.ac.uk/pdbe/static/entry/3ae8_entity_2_top_image-200x200.png "Hetero tetrameric assembly 1 of PDB entry <span class='highlight'>3ae8</span> contains 1 copy of <span class='highlight'>Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial</span>. Top view.")
Chain: C
Length: 140 amino acids
Theoretical weight: 15.3 KDa
Source organism: Sus scrofa
UniProt:
Pfam: Succinate dehydrogenase/Fumarate reductase transmembrane subunit
InterPro:
Length: 140 amino acids
Theoretical weight: 15.3 KDa
Source organism: Sus scrofa
UniProt:
- Canonical: D0VWV4 (Residues: 30-169; Coverage: 83%)
Pfam: Succinate dehydrogenase/Fumarate reductase transmembrane subunit
InterPro:
- Succinate dehydrogenase, cytochrome b556 subunit
- Fumarate reductase/succinate dehydrogenase, transmembrane subunit
- Succinate dehydrogenase/fumarate reductase type B, transmembrane subunit
- Succinate dehydrogenase, cytochrome b subunit, conserved site
Chain: D
Length: 103 amino acids
Theoretical weight: 10.94 KDa
Source organism: Sus scrofa
UniProt:
Pfam: CybS, succinate dehydrogenase cytochrome B small subunit
InterPro:
Length: 103 amino acids
Theoretical weight: 10.94 KDa
Source organism: Sus scrofa
UniProt:
- Canonical: A5GZW8 (Residues: 57-159; Coverage: 65%)
Pfam: CybS, succinate dehydrogenase cytochrome B small subunit
InterPro:
- Fumarate reductase/succinate dehydrogenase, transmembrane subunit
- Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, CybS
![Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial in PDB entry 3ae8, assembly 1, front view.](https://www.ebi.ac.uk/pdbe/static/entry/3ae8_entity_4_front_image-200x200.png "Hetero tetrameric assembly 1 of PDB entry <span class='highlight'>3ae8</span> contains 1 copy of <span class='highlight'>Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial</span>. Front view.")
![Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial in PDB entry 3ae8, assembly 1, side view.](https://www.ebi.ac.uk/pdbe/static/entry/3ae8_entity_4_side_image-200x200.png "Hetero tetrameric assembly 1 of PDB entry <span class='highlight'>3ae8</span> contains 1 copy of <span class='highlight'>Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial</span>. Side view.")
![Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial in PDB entry 3ae8, assembly 1, top view.](https://www.ebi.ac.uk/pdbe/static/entry/3ae8_entity_4_top_image-200x200.png "Hetero tetrameric assembly 1 of PDB entry <span class='highlight'>3ae8</span> contains 1 copy of <span class='highlight'>Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial</span>. Top view.")