Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, CybS (IPR007992)

Short name: CybS

Family relationships



This family consists of mitochondrial succinate dehydrogenase [ubiquinone] cytochrome b small subunit CybS and import inner membrane translocase subunit Tim18.

CybS is a membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q) [PMID: 15989954].

In Saccharomyces cerevisiae, Tim18 is a component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. The TIM22 complex forms a twin-pore translocase that uses the membrane potential as external driving force. Its role in the complex is unclear but it may be involved in the assembly and stabilisation of the TIM22 complex [PMID: 10648604, PMID: 10637294, PMID: 14504216].

GO terms

Biological Process

No terms assigned in this category.

Molecular Function

No terms assigned in this category.

Cellular Component

GO:0016021 integral component of membrane
GO:0005740 mitochondrial envelope

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.