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Contents |
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206 a.a.
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205 a.a.
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150 a.a.
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100 a.a.
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150 a.a.
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129 a.a.
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127 a.a.
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98 a.a.
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117 a.a.
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123 a.a.
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114 a.a.
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96 a.a.
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88 a.a.
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82 a.a.
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80 a.a.
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55 a.a.
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79 a.a.
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85 a.a.
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218 a.a.
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51 a.a.
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* Residue conservation analysis
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Obsolete entry |
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PDB id:
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| Name: |
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Ribosome
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Title:
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Crystal structure of the bacterial ribosome from escherichia coli at 3.5 a resolution. This file contains the 30s subunit of one 70s ribosome. The entire crystal structure contains two 70s ribosomes and is described in remark 400.
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Structure:
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16s ribosomal RNA. Chain: a. 30s ribosomal protein s3. Chain: c. 30s ribosomal protein s4. Chain: d. 30s ribosomal protein s5. Chain: e. 30s ribosomal protein s6.
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Source:
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Escherichia coli. Organism_taxid: 562. Strain: mre600. Strain: mre600
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Biol. unit:
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21mer (from
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Resolution:
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3.46Å
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R-factor:
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0.279
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R-free:
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0.331
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Authors:
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B.S.Schuwirth,M.A.Borovinskaya,C.W.Hau,W.Zhang,A.Vila-Sanjurjo, J.M.Holton,J.H.D.Cate
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Key ref:
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B.S.Schuwirth
et al.
(2005).
Structures of the bacterial ribosome at 3.5 A resolution.
Science,
310,
827-834.
PubMed id:
DOI:
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Date:
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30-Aug-05
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Release date:
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08-Nov-05
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PROCHECK
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Headers
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References
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P0A7V3
(RS3_ECOLI) -
30S ribosomal protein S3 from Escherichia coli (strain K12)
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Seq:
Struc:
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233 a.a.
206 a.a.
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P0A7V8
(RS4_ECOLI) -
30S ribosomal protein S4 from Escherichia coli (strain K12)
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Seq:
Struc:
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206 a.a.
205 a.a.
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P0A7W1
(RS5_ECOLI) -
30S ribosomal protein S5 from Escherichia coli (strain K12)
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Seq:
Struc:
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167 a.a.
150 a.a.
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P02358
(RS6_ECOLI) -
30S ribosomal protein S6 from Escherichia coli (strain K12)
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Seq:
Struc:
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135 a.a.
100 a.a.
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P02359
(RS7_ECOLI) -
30S ribosomal protein S7 from Escherichia coli (strain K12)
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Seq:
Struc:
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179 a.a.
150 a.a.
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P0A7W7
(RS8_ECOLI) -
30S ribosomal protein S8 from Escherichia coli (strain K12)
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Seq:
Struc:
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130 a.a.
129 a.a.
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P0A7X3
(RS9_ECOLI) -
30S ribosomal protein S9 from Escherichia coli (strain K12)
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Seq:
Struc:
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130 a.a.
127 a.a.
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P0A7R5
(RS10_ECOLI) -
30S ribosomal protein S10 from Escherichia coli (strain K12)
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Seq:
Struc:
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103 a.a.
98 a.a.
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P0A7R9
(RS11_ECOLI) -
30S ribosomal protein S11 from Escherichia coli (strain K12)
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Seq:
Struc:
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129 a.a.
117 a.a.
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P0A7S3
(RS12_ECOLI) -
30S ribosomal protein S12 from Escherichia coli (strain K12)
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Seq:
Struc:
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124 a.a.
123 a.a.
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P0A7S9
(RS13_ECOLI) -
30S ribosomal protein S13 from Escherichia coli (strain K12)
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Seq:
Struc:
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118 a.a.
114 a.a.
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P0A7T3
(RS16_ECOLI) -
30S ribosomal protein S16 from Escherichia coli (strain K12)
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Seq:
Struc:
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82 a.a.
82 a.a.
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P0A7T7
(RS18_ECOLI) -
30S ribosomal protein S18 from Escherichia coli (strain K12)
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Seq:
Struc:
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75 a.a.
55 a.a.
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P0A7U3
(RS19_ECOLI) -
30S ribosomal protein S19 from Escherichia coli (strain K12)
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Seq:
Struc:
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92 a.a.
79 a.a.
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P0A7U7
(RS20_ECOLI) -
30S ribosomal protein S20 from Escherichia coli (strain K12)
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|
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Seq:
Struc:
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87 a.a.
85 a.a.
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DOI no:
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Science
310:827-834
(2005)
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PubMed id:
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| |
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Structures of the bacterial ribosome at 3.5 A resolution.
|
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B.S.Schuwirth,
M.A.Borovinskaya,
C.W.Hau,
W.Zhang,
A.Vila-Sanjurjo,
J.M.Holton,
J.H.Cate.
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ABSTRACT
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We describe two structures of the intact bacterial ribosome from Escherichia
coli determined to a resolution of 3.5 angstroms by x-ray crystallography. These
structures provide a detailed view of the interface between the small and large
ribosomal subunits and the conformation of the peptidyl transferase center in
the context of the intact ribosome. Differences between the two ribosomes reveal
a high degree of flexibility between the head and the rest of the small subunit.
Swiveling of the head of the small subunit observed in the present structures,
coupled to the ratchet-like motion of the two subunits observed previously,
suggests a mechanism for the final movements of messenger RNA (mRNA) and
transfer RNAs (tRNAs) during translocation.
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Selected figure(s)
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Figure 6.
Fig. 6. Molecular interactions in the intersubunit bridges. (A)
Contact between S13 and L5 in ribosome I. (B) Contact between
S13 and L5 in ribosome II. Only the C  traces for the
proteins are shown, because protein side chains are not clear in
the electron density of either ribosome. Residues that become
inaccessible to solvent (44) are indicated in orange for L5 and
in yellow for S13 and S19. The direction of view is indicated in
the center. (C) Molecular interactions in bridge B3. (D)
Molecular interactions in bridge B7a. (E) Molecular interactions
in bridge B6. Waters modeled at the interface are shown as red
spheres inside the water-accessible volume, green mesh. (F)
Close approach of phosphates at the subunit interface near
bridge B2c. Distances (in angstroms) between phosphate oxygens
are marked.
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Figure 7.
Fig. 7. Intersubunit bridges B2a and B4. (A) Minor-groove
interactions between H69 and h44 and h45, broken down by region.
Atoms within hydrogen-bonding distance, as mentioned in the
text, are connected by dashed lines. (B) Molecular interactions
in bridge B4. Protein S15 in the 30S subunit is in blue, with
relevant side chains in green. The interaction is viewed from
the left side of Fig. 5A (left) and from the right side of Fig.
5A (right). Electron density is visible for the side chain of
Arg88 (R88) in ribosome II, but not in ribosome I. Other amino
acid abbreviations: I, Ile; L, Leu; V, Val; A, Ala; Q, Gln.
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The above figures are
reprinted
by permission from the AAAs:
Science
(2005,
310,
827-834)
copyright 2005.
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Figures were
selected
by an automated process.
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Literature references that cite this PDB file's key reference
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PubMed id
|
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Reference
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W.A.Hendrickson
(2013).
Evolution of diffraction methods for solving crystal structures.
|
| |
Acta Crystallogr A,
69,
51-59.
|
|
|
|
|
|
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D.J.Ramrath,
H.Yamamoto,
K.Rother,
D.Wittek,
M.Pech,
T.Mielke,
J.Loerke,
P.Scheerer,
P.Ivanov,
Y.Teraoka,
O.Shpanchenko,
K.H.Nierhaus,
and
C.M.Spahn
(2012).
The complex of tmRNA-SmpB and EF-G on translocating ribosomes.
|
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Nature,
485,
526-529.
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PDB codes:
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M.Selmer,
Y.G.Gao,
A.Weixlbaumer,
and
V.Ramakrishnan
(2012).
Ribosome engineering to promote new crystal forms.
|
| |
Acta Crystallogr D Biol Crystallogr,
68,
578-583.
|
|
|
|
|
|
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S.Melnikov,
A.Ben-Shem,
N.Garreau de Loubresse,
L.Jenner,
G.Yusupova,
and
M.Yusupov
(2012).
One core, two shells: bacterial and eukaryotic ribosomes.
|
| |
Nat Struct Mol Biol,
19,
560-567.
|
|
|
|
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|
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A.Petrov,
G.Kornberg,
S.O'Leary,
A.Tsai,
S.Uemura,
and
J.D.Puglisi
(2011).
Dynamics of the translational machinery.
|
| |
Curr Opin Struct Biol,
21,
137-145.
|
|
|
|
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|
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A.S.Yassin,
M.E.Haque,
P.P.Datta,
K.Elmore,
N.K.Banavali,
L.L.Spremulli,
and
R.K.Agrawal
(2011).
Insertion domain within mammalian mitochondrial translation initiation factor 2 serves the role of eubacterial initiation factor 1.
|
| |
Proc Natl Acad Sci U S A,
108,
3918-3923.
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PDB codes:
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A.Vendeville,
D.Larivière,
and
E.Fourmentin
(2011).
An inventory of the bacterial macromolecular components and their spatial organization.
|
| |
FEMS Microbiol Rev,
35,
395-414.
|
|
|
|
|
|
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C.Chen,
B.Stevens,
J.Kaur,
D.Cabral,
H.Liu,
Y.Wang,
H.Zhang,
G.Rosenblum,
Z.Smilansky,
Y.E.Goldman,
and
B.S.Cooperman
(2011).
Single-molecule fluorescence measurements of ribosomal translocation dynamics.
|
| |
Mol Cell,
42,
367-377.
|
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|
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|
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C.Geary,
A.Chworos,
and
L.Jaeger
(2011).
Promoting RNA helical stacking via A-minor junctions.
|
| |
Nucleic Acids Res,
39,
1066-1080.
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|
|
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|
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D.Huber,
N.Rajagopalan,
S.Preissler,
M.A.Rocco,
F.Merz,
G.Kramer,
and
B.Bukau
(2011).
SecA interacts with ribosomes in order to facilitate posttranslational translocation in bacteria.
|
| |
Mol Cell,
41,
343-353.
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D.N.Ermolenko,
and
H.F.Noller
(2011).
mRNA translocation occurs during the second step of ribosomal intersubunit rotation.
|
| |
Nat Struct Mol Biol,
18,
457-462.
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|
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|
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D.N.Wilson,
and
R.Beckmann
(2011).
The ribosomal tunnel as a functional environment for nascent polypeptide folding and translational stalling.
|
| |
Curr Opin Struct Biol,
21,
274-282.
|
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|
|
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D.V.Fedyukina,
and
S.Cavagnero
(2011).
Protein folding at the exit tunnel.
|
| |
Annu Rev Biophys,
40,
337-359.
|
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|
|
|
|
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F.J.Blanco,
and
G.Montoya
(2011).
Transient DNA / RNA-protein interactions.
|
| |
FEBS J,
278,
1643-1650.
|
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H.Ramu,
N.Vázquez-Laslop,
D.Klepacki,
Q.Dai,
J.Piccirilli,
R.Micura,
and
A.S.Mankin
(2011).
Nascent peptide in the ribosome exit tunnel affects functional properties of the A-site of the peptidyl transferase center.
|
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Mol Cell,
41,
321-330.
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J.Fu,
J.B.Munro,
S.C.Blanchard,
and
J.Frank
(2011).
Cryoelectron microscopy structures of the ribosome complex in intermediate states during tRNA translocation.
|
| |
Proc Natl Acad Sci U S A,
108,
4817-4821.
|
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|
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|
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K.Kipper,
S.Sild,
C.Hetényi,
J.Remme,
and
A.Liiv
(2011).
Pseudouridylation of 23S rRNA helix 69 promotes peptide release by release factor RF2 but not by release factor RF1.
|
| |
Biochimie,
93,
834-844.
|
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|
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L.F.Estrozi,
D.Boehringer,
S.O.Shan,
N.Ban,
and
C.Schaffitzel
(2011).
Cryo-EM structure of the E. coli translating ribosome in complex with SRP and its receptor.
|
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Nat Struct Mol Biol,
18,
88-90.
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PDB code:
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L.R.Cruz-Vera,
M.S.Sachs,
C.L.Squires,
and
C.Yanofsky
(2011).
Nascent polypeptide sequences that influence ribosome function.
|
| |
Curr Opin Microbiol,
14,
160-166.
|
|
|
|
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|
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M.V.Rodnina,
and
W.Wintermeyer
(2011).
The ribosome as a molecular machine: the mechanism of tRNA-mRNA movement in translocation.
|
| |
Biochem Soc Trans,
39,
658-662.
|
|
|
|
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|
|
Q.Sun,
A.Vila-Sanjurjo,
and
M.O'Connor
(2011).
Mutations in the intersubunit bridge regions of 16S rRNA affect decoding and subunit-subunit interactions on the 70S ribosome.
|
| |
Nucleic Acids Res,
39,
3321-3330.
|
|
|
|
|
|
|
S.Bhushan,
T.Hoffmann,
B.Seidelt,
J.Frauenfeld,
T.Mielke,
O.Berninghausen,
D.N.Wilson,
and
R.Beckmann
(2011).
SecM-stalled ribosomes adopt an altered geometry at the peptidyl transferase center.
|
| |
PLoS Biol,
9,
e1000581.
|
|
|
|
|
|
|
S.Feng,
H.Li,
J.Zhao,
K.Pervushin,
K.Lowenhaupt,
T.U.Schwartz,
and
P.Dröge
(2011).
Alternate rRNA secondary structures as regulators of translation.
|
| |
Nat Struct Mol Biol,
18,
169-176.
|
|
|
PDB code:
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|
|
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|
|
|
T.L.Grove,
J.S.Benner,
M.I.Radle,
J.H.Ahlum,
B.J.Landgraf,
C.Krebs,
and
S.J.Booker
(2011).
A radically different mechanism for S-adenosylmethionine-dependent methyltransferases.
|
| |
Science,
332,
604-607.
|
|
|
|
|
|
|
W.Li,
L.G.Trabuco,
K.Schulten,
and
J.Frank
(2011).
Molecular dynamics of EF-G during translocation.
|
| |
Proteins,
79,
1478-1486.
|
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|
PDB code:
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|
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|
|
X.Qu,
J.D.Wen,
L.Lancaster,
H.F.Noller,
C.Bustamante,
and
I.Tinoco
(2011).
The ribosome uses two active mechanisms to unwind messenger RNA during translation.
|
| |
Nature,
475,
118-121.
|
|
|
|
|
|
|
Z.Guo,
M.Gibson,
S.Sitha,
S.Chu,
and
U.Mohanty
(2011).
Role of large thermal fluctuations and magnesium ions in t-RNA selectivity of the ribosome.
|
| |
Proc Natl Acad Sci U S A,
108,
3947-3951.
|
|
|
|
|
|
|
A.Ben-Shem,
L.Jenner,
G.Yusupova,
and
M.Yusupov
(2010).
Crystal structure of the eukaryotic ribosome.
|
| |
Science,
330,
1203-1209.
|
|
|
PDB codes:
|
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|
|
|
|
|
|
A.E.Bunner,
A.H.Beck,
and
J.R.Williamson
(2010).
Kinetic cooperativity in Escherichia coli 30S ribosomal subunit reconstitution reveals additional complexity in the assembly landscape.
|
| |
Proc Natl Acad Sci U S A,
107,
5417-5422.
|
|
|
|
|
|
|
A.E.Bunner,
S.Nord,
P.M.Wikström,
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Structure,
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P.M.Petrone,
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RNA,
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R.A.Marshall,
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PDB codes:
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R.D.Pai,
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RNA,
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Discovery and characterization of a new bacterial candidate division by an anaerobic sludge digester metagenomic approach.
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Environ Microbiol,
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Synthesis and solution conformation studies of the modified nucleoside N(4),2'-O-dimethylcytidine (m(4)Cm) and its analogues.
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The methyltransferase YfgB/RlmN is responsible for modification of adenosine 2503 in 23S rRNA.
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RNA,
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From knotted to nested RNA structures: a variety of computational methods for pseudoknot removal.
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RNA,
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Nature,
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Mutations in conserved helix 69 of 23S rRNA of Thermus thermophilus that affect capreomycin resistance but not posttranscriptional modifications.
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PDB codes:
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W.Rypniewski,
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RNA,
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PDB codes:
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W.Zhang,
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Structure,
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Visualization of the hybrid state of tRNA binding promoted by spontaneous ratcheting of the ribosome.
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Mol Cell,
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Structural and functional analysis of the E. coli NusB-S10 transcription antitermination complex.
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Mol Cell,
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PDB codes:
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Z.Xu,
H.C.O'Farrell,
J.P.Rife,
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Nat Struct Mol Biol,
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In vivo assembling of bacterial ribosomal protein L11 into yeast ribosomes makes the particles sensitive to the prokaryotic specific antibiotic thiostrepton.
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Nucleic Acids Res,
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Interactions and dynamics of the Shine Dalgarno helix in the 70S ribosome.
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Proc Natl Acad Sci U S A,
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PDB codes:
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A.L.Manuell,
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Structure of the chloroplast ribosome: novel domains for translation regulation.
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Nat Struct Mol Biol,
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PDB codes:
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RNA,
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Mol Cell,
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Induced-fit tightens pleuromutilins binding to ribosomes and remote interactions enable their selectivity.
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Proc Natl Acad Sci U S A,
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Saturation mutagenesis of a +1 programmed frameshift-inducing mRNA sequence derived from a yeast retrotransposon.
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RNA,
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Structures of tRNAs with an expanded anticodon loop in the decoding center of the 30S ribosomal subunit.
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RNA,
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PDB codes:
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C.S.Chow,
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ACS Chem Biol,
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RNA,
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Structures of modified eEF2 80S ribosome complexes reveal the role of GTP hydrolysis in translocation.
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EMBO J,
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RNA,
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Methyltransferase that modifies guanine 966 of the 16 S rRNA: functional identification and tertiary structure.
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J Biol Chem,
282,
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E.C.Kouvela,
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Changes in the conformation of 5S rRNA cause alterations in principal functions of the ribosomal nanomachine.
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Nucleic Acids Res,
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Nucleic Acids Res,
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Nucleic Acids Res,
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PDB code:
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RF3 induces ribosomal conformational changes responsible for dissociation of class I release factors.
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Cell,
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H.K.Lamb,
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Selective quenching of fluorescence from unbound oligonucleotides by gold nanoparticles as a probe of RNA structure.
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RNA,
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PDB codes:
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H.Muto,
H.Nakatogawa,
and
K.Ito
(2006).
Genetically encoded but nonpolypeptide prolyl-tRNA functions in the A site for SecM-mediated ribosomal stall.
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| |
Mol Cell,
22,
545-552.
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I.K.Ali,
L.Lancaster,
J.Feinberg,
S.Joseph,
and
H.F.Noller
(2006).
Deletion of a conserved, central ribosomal intersubunit RNA bridge.
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| |
Mol Cell,
23,
865-874.
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J.Dresios,
P.Panopoulos,
and
D.Synetos
(2006).
Eukaryotic ribosomal proteins lacking a eubacterial counterpart: important players in ribosomal function.
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| |
Mol Microbiol,
59,
1651-1663.
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J.Kondo,
A.Urzhumtsev,
and
E.Westhof
(2006).
Two conformational states in the crystal structure of the Homo sapiens cytoplasmic ribosomal decoding A site.
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| |
Nucleic Acids Res,
34,
676-685.
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PDB code:
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J.S.Feinberg,
and
S.Joseph
(2006).
Ribose 2'-hydroxyl groups in the 5' strand of the acceptor arm of P-site tRNA are not essential for EF-G catalyzed translocation.
|
| |
RNA,
12,
580-588.
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J.W.Kieltyka,
and
C.S.Chow
(2006).
Probing RNA hairpins with cobalt(III)hexammine and electrospray ionization mass spectrometry.
|
| |
J Am Soc Mass Spectrom,
17,
1376-1382.
|
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J.Xu,
M.C.Kiel,
A.Golshani,
J.G.Chosay,
H.Aoki,
and
M.C.Ganoza
(2006).
Molecular localization of a ribosome-dependent ATPase on Escherichia coli ribosomes.
|
| |
Nucleic Acids Res,
34,
1158-1165.
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K.Mitra,
and
J.Frank
(2006).
Ribosome dynamics: insights from atomic structure modeling into cryo-electron microscopy maps.
|
| |
Annu Rev Biophys Biomol Struct,
35,
299-317.
|
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K.Réblová,
F.Lankas,
F.Rázga,
M.V.Krasovska,
J.Koca,
and
J.Sponer
(2006).
Structure, dynamics, and elasticity of free 16s rRNA helix 44 studied by molecular dynamics simulations.
|
| |
Biopolymers,
82,
504-520.
|
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K.S.Long,
J.Poehlsgaard,
C.Kehrenberg,
S.Schwarz,
and
B.Vester
(2006).
The Cfr rRNA methyltransferase confers resistance to Phenicols, Lincosamides, Oxazolidinones, Pleuromutilins, and Streptogramin A antibiotics.
|
| |
Antimicrob Agents Chemother,
50,
2500-2505.
|
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|
L.R.Cruz-Vera,
M.Gong,
and
C.Yanofsky
(2006).
Changes produced by bound tryptophan in the ribosome peptidyl transferase center in response to TnaC, a nascent leader peptide.
|
| |
Proc Natl Acad Sci U S A,
103,
3598-3603.
|
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M.Bubunenko,
A.Korepanov,
D.L.Court,
I.Jagannathan,
D.Dickinson,
B.R.Chaudhuri,
M.B.Garber,
and
G.M.Culver
(2006).
30S ribosomal subunits can be assembled in vivo without primary binding ribosomal protein S15.
|
| |
RNA,
12,
1229-1239.
|
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|
|
M.Halic,
M.Blau,
T.Becker,
T.Mielke,
M.R.Pool,
K.Wild,
I.Sinning,
and
R.Beckmann
(2006).
Following the signal sequence from ribosomal tunnel exit to signal recognition particle.
|
| |
Nature,
444,
507-511.
|
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|
PDB codes:
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M.Jiang,
K.Datta,
A.Walker,
J.Strahler,
P.Bagamasbad,
P.C.Andrews,
and
J.R.Maddock
(2006).
The Escherichia coli GTPase CgtAE is involved in late steps of large ribosome assembly.
|
| |
J Bacteriol,
188,
6757-6770.
|
|
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|
|
N.B.Leontis,
A.Lescoute,
and
E.Westhof
(2006).
The building blocks and motifs of RNA architecture.
|
| |
Curr Opin Struct Biol,
16,
279-287.
|
|
|
|
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|
|
N.Foloppe,
N.Matassova,
and
F.Aboul-Ela
(2006).
Towards the discovery of drug-like RNA ligands?
|
| |
Drug Discov Today,
11,
1019-1027.
|
|
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|
|
N.Gao,
and
J.Frank
(2006).
A library of RNA bridges.
|
| |
Nat Chem Biol,
2,
231-232.
|
|
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|
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|
|
N.Kirthi,
B.Roy-Chaudhuri,
T.Kelley,
and
G.M.Culver
(2006).
A novel single amino acid change in small subunit ribosomal protein S5 has profound effects on translational fidelity.
|
| |
RNA,
12,
2080-2091.
|
|
|
|
|
|
|
N.S.Sato,
N.Hirabayashi,
I.Agmon,
A.Yonath,
and
T.Suzuki
(2006).
Comprehensive genetic selection revealed essential bases in the peptidyl-transferase center.
|
| |
Proc Natl Acad Sci U S A,
103,
15386-15391.
|
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|
|
N.Spacková,
and
J.Sponer
(2006).
Molecular dynamics simulations of sarcin-ricin rRNA motif.
|
| |
Nucleic Acids Res,
34,
697-708.
|
|
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|
|
|
|
O.Rackham,
K.Wang,
and
J.W.Chin
(2006).
Functional epitopes at the ribosome subunit interface.
|
| |
Nat Chem Biol,
2,
254-258.
|
|
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|
T.Adilakshmi,
R.A.Lease,
and
S.A.Woodson
(2006).
Hydroxyl radical footprinting in vivo: mapping macromolecular structures with synchrotron radiation.
|
| |
Nucleic Acids Res,
34,
e64.
|
|
|
|
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|
|
T.Hosaka,
J.Xu,
and
K.Ochi
(2006).
Increased expression of ribosome recycling factor is responsible for the enhanced protein synthesis during the late growth phase in an antibiotic-overproducing Streptomyces coelicolor ribosomal rpsL mutant.
|
| |
Mol Microbiol,
61,
883-897.
|
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V.Berk,
W.Zhang,
R.D.Pai,
J.H.Cate,
and
J.H.Cate
(2006).
Structural basis for mRNA and tRNA positioning on the ribosome.
|
| |
Proc Natl Acad Sci U S A,
103,
15830-15834.
|
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|
PDB codes:
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W.Li,
J.Sengupta,
B.K.Rath,
and
J.Frank
(2006).
Functional conformations of the L11-ribosomal RNA complex revealed by correlative analysis of cryo-EM and molecular dynamics simulations.
|
| |
RNA,
12,
1240-1253.
|
|
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PDB code:
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Y.Timsit,
F.Allemand,
C.Chiaruttini,
and
M.Springer
(2006).
Coexistence of two protein folding states in the crystal structure of ribosomal protein L20.
|
| |
EMBO Rep,
7,
1013-1018.
|
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PDB code:
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The most recent references are shown first.
Citation data come partly from CiteXplore and partly
from an automated harvesting procedure. Note that this is likely to be
only a partial list as not all journals are covered by
either method. However, we are continually building up the citation data
so more and more references will be included with time.
Where a reference describes a PDB structure, the PDB
codes are
shown on the right.
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| |
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