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UniProt functional annotation for P0A7V3 | ||
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| UniProt codes: P0A7V3, P02352. |
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| Organism: | |
Escherichia coli (strain K12). |
| Taxonomy: | |
Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia. |
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| Function: | |
Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity). {ECO:0000250}. |
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| Function: | |
Plays a role in mRNA unwinding by the ribosome, possibly by forming part of a processivity clamp. {ECO:0000269|PubMed:15652481}. |
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| Subunit: | |
Part of the 30S ribosomal subunit (PubMed:387449, PubMed:7556101, PubMed:12809609, PubMed:16272117, PubMed:27934701, PubMed:10094780, PubMed:12244297, PubMed:27906160, PubMed:27906161, PubMed:28077875). Forms a tight complex with proteins S10 and S14 (By similarity). With proteins S4 and S5 encircles the mRNA as it enters the ribosome, which may play a role in mRNA helicase processivity. Some nascent polypeptide chains are able to cross-link to this protein in situ. {ECO:0000255|HAMAP-Rule:MF_01309, ECO:0000269|PubMed:10094780, ECO:0000269|PubMed:12244297, ECO:0000269|PubMed:12809609, ECO:0000269|PubMed:16272117, ECO:0000269|PubMed:27906160, ECO:0000269|PubMed:27906161, ECO:0000269|PubMed:27934701, ECO:0000269|PubMed:28077875, ECO:0000269|PubMed:387449, ECO:0000269|PubMed:7556101}. |
| Mass spectrometry: | |
Mass=25851.9; Method=MALDI; Evidence={ECO:0000269|PubMed:10094780}; |
| Similarity: | |
Belongs to the universal ribosomal protein uS3 family. {ECO:0000305}. |
Annotations taken from UniProtKB at the EBI.