EMDB EMD-9259

Single particle reconstruction
3.9Å resolution

The structure of the Plasmodium falciparum 20S proteasome in complex with one PA28 activator

Map released:
Last modified:
Overview of EMD-9259
Source organism: Plasmodium falciparum 3D7 [36329]
Fitted atomic model: 6mux
Related EM entry by publication: EMD-9257, EMD-9258
Primary publication:
The structure of the PA28-20S proteasome complex from Plasmodium falciparum and implications for proteostasis.
Xie SC, Metcalfe RD, Hanssen E, Yang T, Gillett DL, Leis AP, Morton CJ, Kuiper MJ, Parker MW, Spillman NJ, Wong W, Tsu C, Dick LR, Griffin MDW, Tilley L
Nat Microbiol - (2019)
PMID: 31384003

Function and Biology Details

Sample name: 20S proteasome/PA28 complex.
Proteins: 20S proteasome/PA28 complex., Plasmodium falciparum 20S proteasome, 11S activator of the Plasmodium falciparum proteasome., 20S proteasome alpha-1 subunit, 20S proteasome alpha-2 subunit, 20S proteasome alpha-3 subunit, 20S proteasome alpha-4 subunit, 20S proteasome alpha-5 subunit, 20S proteasome alpha-6 subunit, 20S proteasome alpha-7 subunit, 20S proteasome beta-1 subunit, 20S proteasome beta-2 subunit, 20S proteasome beta-3 subunit, 20S proteasome beta-4 subunit, 20S proteasome beta-5 subunit, 20S proteasome beta-6 subunit, 20S proteasome beta-7 subunit, Proteasome activator PA28

Experimental Information Details

Resolution: 3.9Å
Resolution method: FSC 0.143 CUT-OFF
Applied symmetry: C1
Reconstruction software: RELION
Microscope: FEI TALOS ARCTICA
Detector: GATAN K2 QUANTUM (4k x 4k)