EMDB EMD-22842

Single particle reconstruction
4.25Å resolution

Ebola virus GP (mucin deleted, Makona strain) bound to antibody Fab EBOV-293

Map released:
Overview of EMD-22842
Source organisms:
Fitted atomic model: 7kex
Primary publication:
Convergence of a common solution for broad ebolavirus neutralization by glycan cap-directed human antibodies.
Murin CD, Gilchuk P, Ilinykh PA, Huang K, Kuzmina N, Shen X, Bruhn JF, Bryan AL, Davidson E, Doranz BJ, Williamson LE, Copps J, Alkutkar T, Flyak AI, Bukreyev A, Crowe Jr JE, Ward AB
Cell Rep 35 108984-108984 (2021)
PMID: 33852862

Function and Biology Details

Sample name: Complex of Ebola virus GP (mucin deleted, Makona strain) bound to the antibody Fab EBOV-293 and EBOV-515
Ligand: 2-acetamido-2-deoxy-beta-D-glucopyranose
Proteins: Complex of Ebola virus GP (mucin deleted, Makona strain) bound to the antibody Fab EBOV-293 and EBOV-515, Ebola virus GP (mucin deleted, Makona strain), EBOV-293 Fab, Antibody Fab EBOV-293 light chain, Antibody Fab EBOV-293 heavy chain, Virion spike glycoprotein 1, Virion spike glycoprotein 2

Experimental Information Details

Resolution: 4.25Å
Resolution method: FSC 0.143 CUT-OFF
Microscope: FEI TALOS ARCTICA
Detector: GATAN K2 SUMMIT (4k x 4k)