7kex

Electron Microscopy
4.25Å resolution

Ebola virus GP (mucin deleted, Makona strain) bound to antibody Fab EBOV-293

Released:
Source organisms:
Entry authors: Murin CD, Ward AB
Related structures: EMD-22842

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dodecamer (preferred)
Entry contents:
4 distinct polypeptide molecules
Macromolecules (6 distinct):
Antibody Fab EBOV-293 light chain Chains: J, K, L
Molecule details ›
Chains: J, K, L
Length: 232 amino acids
Theoretical weight: 25.22 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Antibody Fab EBOV-293 heavy chain Chains: G, H, I
Molecule details ›
Chains: G, H, I
Length: 244 amino acids
Theoretical weight: 26 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
GP1 Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 313 amino acids
Theoretical weight: 34.98 KDa
Source organism: Ebola virus
Expression system: Homo sapiens
UniProt:
  • Canonical: Q05320 (Residues: 32-309; Coverage: 43%)
Gene name: GP
GP2 Chains: D, E, F
Molecule details ›
Chains: D, E, F
Length: 203 amino acids
Theoretical weight: 22.16 KDa
Source organism: Ebola virus
Expression system: Homo sapiens
UniProt:
  • Canonical: Q05320 (Residues: 461-629; Coverage: 26%)
Gene name: GP

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, BMA
Carbohydrate polymer : NEW Components: NAG, BMA, MAN
1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 4.25Å
Relevant EMDB volumes: EMD-22842
Expression system: Homo sapiens