EMDB › EMD-22327

Single particle reconstruction
3.36Å resolution

Cryo-EM structure of P. falciparum VAR2CSA NF54 core in complex with CSA at 3.36 A

Map released:
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Overview of EMD-22327
Source organism: Plasmodium falciparum (isolate NF54) [5843]
Fitted atomic model: 7jgh
Related EM entries by publication: EMD-22323, EMD-22324, EMD-22325, EMD-22326
Primary publication:
Structural basis for placental malaria mediated by Plasmodium falciparum VAR2CSA.
Ma R, Lian T, Huang R, Renn JP, Petersen JD, Zimmerberg J, Duffy PE, Tolia NH
Nat Microbiol 6 380-391 (2021)
PMID: 33452495

Function and Biology Details

Sample name: VAR2CSA NF54 core in complex with CSA
Ligand: 2-acetamido-2-deoxy-4-O-sulfo-beta-D-galactopyranose
Proteins: VAR2CSA NF54 core in complex with CSA, Erythrocyte membrane protein 1

Experimental Information Details

Resolution: 3.36Å
Resolution method: FSC 0.143 CUT-OFF
Microscope: FEI TITAN KRIOS
Detector: GATAN K2 SUMMIT (4k x 4k)
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