7jgh

Electron Microscopy
3.36Å resolution

Cryo-EM structure of P. falciparum VAR2CSA NF54 core in complex with CSA at 3.36 A

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
Erythrocyte membrane protein 1 Chain: A
Molecule details ›
Chain: A
Length: 2653 amino acids
Theoretical weight: 308.71 KDa
Source organism: Plasmodium falciparum NF54
Expression system: Homo sapiens
UniProt:
  • Canonical: W7K270 (Residues: 1-2642; Coverage: 94%)
Gene name: PFNF54_03544
Sequence domains:

Ligands and Environments

Carbohydrate polymer : NEW Components: ASG, BDP
1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.36Å
Relevant EMDB volumes: EMD-22327
Expression system: Homo sapiens