EMDB EMD-20584

Single particle reconstruction
3.5Å resolution

A potent cross-neutralizing antibody targeting the fusion glycoprotein inhibits Nipah virus and Hendra virus infection

Map released:
Last modified:
Overview of EMD-20584
Source organisms:
Fitted atomic model: 6tys
Primary publication:
An antibody against the F glycoprotein inhibits Nipah and Hendra virus infections.
Dang HV, Chan YP, Park YJ, Snijder J, Da Silva SC, Vu B, Yan L, Feng YR, Rockx B, Geisbert TW, Mire CE, Broder CC, Veesler D
Nat.Struct.Mol.Biol. - (2019)
PMID: 31570878

Function and Biology Details

Sample name: Nipah virus fusion (F) glycoprotein in complex with the 5B3 antibody Fab fragment
Ligands: N-ACETYL-D-GLUCOSAMINE, ALPHA-D-MANNOSE, BETA-D-MANNOSE
Proteins: Nipah virus fusion (F) glycoprotein in complex with the 5B3 antibody Fab fragment, Fusion glycoprotein F0, 5B3 antibody, Fusion glycoprotein F0, 5B3 antibody heavy chain, 5B3 antibody light chain

Experimental Information Details

Resolution: 3.5Å
Resolution method: FSC 0.143 CUT-OFF
Applied symmetry: C3
Reconstruction software: cryoSPARC
Microscope: FEI TITAN KRIOS
Detector: GATAN K2 SUMMIT (4k x 4k)