6tys

Electron Microscopy
3.5Å resolution

A potent cross-neutralizing antibody targeting the fusion glycoprotein inhibits Nipah virus and Hendra virus infection

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero nonamer (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Fusion glycoprotein F0 Chains: A, B, E
Molecule details ›
Chains: A, B, E
Length: 538 amino acids
Theoretical weight: 59.7 KDa
Source organism: Nipah henipavirus
Expression system: Homo sapiens
UniProt:
  • Canonical: Q9IH63 (Residues: 1-104, 105-495; Coverage: 90%)
Gene name: F
5B3 antibody heavy chain Chains: C, F, H
Molecule details ›
Chains: C, F, H
Length: 120 amino acids
Theoretical weight: 13.25 KDa
Source organism: Mus musculus
Expression system: Mus musculus
5B3 antibody light chain Chains: D, G, L
Molecule details ›
Chains: D, G, L
Length: 107 amino acids
Theoretical weight: 11.52 KDa
Source organism: Mus musculus
Expression system: Mus musculus

Ligands and Environments

3 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.5Å
Relevant EMDB volumes: EMD-20584
Expression systems:
  • Homo sapiens
  • Mus musculus