EMDB EMD-20527

Single particle reconstruction
4.19Å resolution

MERS S0 trimer in complex with antibody G2

Map released:
Overview of EMD-20527
Fitted atomic model: 6pz8
Primary publication:
Structural Definition of a Neutralization-Sensitive Epitope on the MERS-CoV S1-NTD.
Wang N, Rosen O, Wang L, Turner HL, Stevens LJ, Corbett KS, Bowman CA, Pallesen J, Shi W, Zhang Y, Leung K, Kirchdoerfer RN, Becker MM, Denison MR, Chappell JD, Ward AB, Graham BS, McLellan JS
Cell Rep 28 3395-3405.e6 (2019)
PMID: 31553909

Function and Biology Details

Sample name: MERS S0 ectodomain trimer in complex with antibody G2
Ligands: N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ALPHA-D-MANNOSE
Proteins: MERS S0 ectodomain trimer in complex with antibody G2, MERS S0 ectodomain trimer, antibody G2, S protein, S protein, G2 heavy chain, G2 light chain

Experimental Information Details

Resolution: 4.19Å
Resolution method: FSC 0.143 CUT-OFF
Applied symmetry: C3
Reconstruction software: cryoSPARC
Microscope: FEI TITAN KRIOS
Detector: GATAN K2 SUMMIT (4k x 4k)