6pz8

Electron Microscopy
4.19Å resolution

MERS S0 trimer in complex with variable domain of antibody G2

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dodecamer (preferred)
Entry contents:
4 distinct polypeptide molecules
Macromolecules (4 distinct):
Spike glycoprotein Chains: A, E, I
Molecule details ›
Chains: A, E, I
Length: 472 amino acids
Theoretical weight: 51.3 KDa
Source organism: Middle East respiratory syndrome-related coronavirus
Expression system: Homo sapiens
UniProt:
  • Canonical: W5ZZF5 (Residues: 752-1223; Coverage: 35%)
Gene name: S
Spike glycoprotein Chains: B, F, J
Molecule details ›
Chains: B, F, J
Length: 726 amino acids
Theoretical weight: 80.41 KDa
Source organism: Middle East respiratory syndrome-related coronavirus
Expression system: Homo sapiens
UniProt:
  • Canonical: W6A090 (Residues: 18-743; Coverage: 54%)
Gene name: S
Sequence domains: Spike receptor binding domain
G2 heavy chain Chains: C, D, H
Molecule details ›
Chains: C, D, H
Length: 229 amino acids
Theoretical weight: 24.28 KDa
Source organism: Mus musculus
Expression system: Homo sapiens
G2 light chain Chains: G, K, L
Molecule details ›
Chains: G, K, L
Length: 218 amino acids
Theoretical weight: 23.86 KDa
Source organism: Mus musculus
Expression system: Homo sapiens

Ligands and Environments

3 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 4.19Å
Relevant EMDB volumes: EMD-20527
Expression system: Homo sapiens