EMDB EMD-10061

Single particle reconstruction
4.1Å resolution

Cryo-EM structure of mouse cytoplasmic dynein-1 microtubule binding domain bound to microtubules

Map released:
Last modified:
Overview of EMD-10061
Source organisms:
Fitted atomic model: 6rzb
Related EM entry by publication: EMD-10060
Primary publication:
Cryo-EM of dynein microtubule-binding domains shows how an axonemal dynein distorts the microtubule.
Lacey SE, He S, Scheres SH, Carter AP
Elife 8 - (2019)
PMID: 31264960

Function and Biology Details

Sample name: Mouse cytoplasmic dynein-1 microtubule binding domain decorating microtubules
Ligands: GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, GUANOSINE-5'-DIPHOSPHATE, TAXOL
Proteins: Mouse cytoplasmic dynein-1 microtubule binding domain decorating microtubules, Tubulin, dynein-1 microtubule binding, Tubulin alpha-1B chain, Tubulin beta chain, MKIAA0325 protein

Experimental Information Details

Resolution: 4.1Å
Resolution method: FSC 0.143 CUT-OFF
Reconstruction software: RELION
Microscope: FEI TITAN KRIOS
Detector: FEI FALCON III (4k x 4k)