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Peptidase

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Substrates for U74.001: neprosin

Summary Alignment Sequences Sequence features Distribution Literature Substrates

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are thought to be pathologically relevant are indicated by D. Peptide and protein substrates that are not physiologically relevant are indicated by N. Synthetic substrates are indicated by S. Click on the symbol to show only physiological, non-physiological or synthetic substrates, or here to display all substrates. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a protein substrate, click on the UniProt Accession.

Substrate Uniprot Residue range Cleavage Site Cleavage type Evidence P4 P3 P2 P1 P1' P2' P3' P4' Reference CutDB MERNUM
alpha/beta-gliadin MM1 P18573 21-307 peptide-Pro26+Gln-peptide N Val Pro Val Pro Gln Leu Gln Pro Rey et al., 2016
alpha/beta-gliadin MM1 P18573 21-307 peptide-Gln27+Leu-peptide N Pro Val Pro Gln Leu Gln Pro Gln Rey et al., 2016
alpha/beta-gliadin MM1 P18573 21-307 peptide-Pro30+Gln-peptide N Gln Leu Gln Pro Gln Asn Pro Ser Rey et al., 2016
alpha/beta-gliadin MM1 P18573 21-307 peptide-Asn32+Pro-peptide N Gln Pro Gln Asn Pro Ser Gln Gln Rey et al., 2016
alpha/beta-gliadin MM1 P18573 21-307 peptide-Pro33+Ser-peptide N Pro Gln Asn Pro Ser Gln Gln Gln Rey et al., 2016
alpha/beta-gliadin MM1 P18573 21-307 peptide-Pro38+Gln-peptide N Gln Gln Gln Pro Gln Glu Gln Val Rey et al., 2016
alpha/beta-gliadin MM1 P18573 21-307 peptide-Pro43+Leu-peptide N Glu Gln Val Pro Leu Val Gln Gln Rey et al., 2016
alpha/beta-gliadin MM1 P18573 21-307 peptide-Gly52+Gln-peptide N MS Gln Phe Pro Gly Gln Gln Gln Pro Rey et al., 2016
alpha/beta-gliadin MM1 P18573 21-307 peptide-Pro56+Phe-peptide N MS Gln Gln Gln Pro Phe Pro Pro Gln Rey et al., 2016
alpha/beta-gliadin MM1 P18573 21-307 peptide-Pro59+Gln-peptide N MS Pro Phe Pro Pro Gln Gln Pro Tyr Rey et al., 2016
alpha/beta-gliadin MM1 P18573 21-307 peptide-Pro62+Tyr-peptide N MS Pro Gln Gln Pro Tyr Pro Gln Pro Rey et al., 2016
alpha/beta-gliadin MM1 P18573 21-307 peptide-Pro68+Phe-peptide N MS Gln Pro Gln Pro Phe Pro Ser Gln Rey et al., 2016
alpha/beta-gliadin MM1 P18573 21-307 peptide-Pro66+Gln-peptide N MS Tyr Pro Gln Pro Gln Pro Phe Pro Rey et al., 2016
alpha/beta-gliadin MM1 P18573 21-307 peptide-Ser71+Gln-peptide N MS Pro Phe Pro Ser Gln Gln Pro Tyr Rey et al., 2016
alpha/beta-gliadin MM1 P18573 21-307 peptide-Pro74+Tyr-peptide N MS Ser Gln Gln Pro Tyr Leu Gln Leu Rey et al., 2016
alpha/beta-gliadin MM1 P18573 21-307 peptide-Gln77+Leu-peptide N MS Pro Tyr Leu Gln Leu Gln Pro Phe Rey et al., 2016
alpha/beta-gliadin MM1 P18573 21-307 peptide-Pro84+Gln-peptide N MS Phe Pro Gln Pro Gln Leu Pro Tyr Rey et al., 2016
alpha/beta-gliadin MM1 P18573 21-307 peptide-Leu86+Pro-peptide N MS Gln Pro Gln Leu Pro Tyr Pro Gln Rey et al., 2016
alpha/beta-gliadin MM1 P18573 21-307 peptide-Pro91+Gln-peptide N MS Tyr Pro Gln Pro Gln Leu Pro Tyr Rey et al., 2016
alpha/beta-gliadin MM1 P18573 21-307 peptide-Pro98+Gln-peptide N MS Tyr Pro Gln Pro Gln Leu Pro Tyr Rey et al., 2016
alpha/beta-gliadin MM1 P18573 21-307 peptide-Gln104+Pro-peptide N MS Pro Tyr Pro Gln Pro Gln Pro Phe Rey et al., 2016
alpha/beta-gliadin MM1 P18573 21-307 peptide-Pro105+Gln-peptide N MS Tyr Pro Gln Pro Gln Pro Phe Arg Rey et al., 2016
alpha/beta-gliadin MM1 P18573 21-307 peptide-Pro107+Phe-peptide N MS Gln Pro Gln Pro Phe Arg Pro Gln Rey et al., 2016
alpha/beta-gliadin MM1 P18573 21-307 peptide-Pro110+Gln-peptide N MS Pro Phe Arg Pro Gln Gln Pro Tyr Rey et al., 2016
alpha/beta-gliadin MM1 P18573 21-307 peptide-Pro113+Tyr-peptide N MS Pro Gln Gln Pro Tyr Pro Gln Ser Rey et al., 2016
alpha/beta-gliadin MM1 P18573 21-307 peptide-Pro119+Gln-peptide N MS Gln Ser Gln Pro Gln Tyr Ser Gln Rey et al., 2016
alpha/beta-gliadin MM1 P18573 21-307 peptide-Pro124+Gln-peptide N MS Tyr Ser Gln Pro Gln Gln Pro Ile Rey et al., 2016
alpha/beta-gliadin MM1 P18573 21-307 peptide-Gln125+Gln-peptide N MS Ser Gln Pro Gln Gln Pro Ile Ser Rey et al., 2016
alpha/beta-gliadin MM1 P18573 21-307 peptide-Pro127+Ile-peptide N MS Pro Gln Gln Pro Ile Ser Gln Gln Rey et al., 2016
alpha/beta-gliadin MM1 P18573 21-307 peptide-Pro241+Gln-peptide N MS Phe Gln Gln Pro Gln Gln Gln Tyr Rey et al., 2016
alpha/beta-gliadin MM1 P18573 21-307 peptide-Ser255+Gln-peptide N MS Phe Gln Pro Ser Gln Gln Asn Pro Rey et al., 2016
alpha/beta-gliadin MM1 P18573 21-307 peptide-Asn258+Pro-peptide N MS Ser Gln Gln Asn Pro Gln Ala Gln Rey et al., 2016
alpha/beta-gliadin MM1 P18573 21-307 peptide-Pro259+Gln-peptide N MS Gln Gln Asn Pro Gln Ala Gln Gly Rey et al., 2016
alpha/beta-gliadin MM1 P18573 21-307 peptide-Pro267+Gln-peptide N MS Ser Val Gln Pro Gln Gln Leu Pro Rey et al., 2016
alpha/beta-gliadin MM1 P18573 21-307 peptide-Pro271+Gln-peptide N MS Gln Gln Leu Pro Gln Phe Glu Glu Rey et al., 2016
alpha/beta-gliadin MM1 P18573 21-307 peptide-Arg277+Asn-peptide N MS Glu Glu Ile Arg Asn Leu Ala Leu Rey et al., 2016
alpha/beta-gliadin MM1 P18573 21-307 peptide-Asn278+Leu-peptide N MS Glu Ile Arg Asn Leu Ala Leu Glu Rey et al., 2016
alpha/beta-gliadin MM1 P18573 21-307 peptide-Leu279+Ala-peptide N MS Ile Arg Asn Leu Ala Leu Glu Thr Rey et al., 2016
alpha/beta-gliadin MM1 P18573 21-307 peptide-Leu281+Glu-peptide N MS Asn Leu Ala Leu Glu Thr Leu Pro Rey et al., 2016
alpha/beta-gliadin MM1 P18573 21-307 peptide-Pro285+Ala-peptide N MS Glu Thr Leu Pro Ala Met Cys Asn Rey et al., 2016
aprataxin and PNK-like factor Q8IW19 1-511 peptide-Pro20+Gly-peptide N Ala Leu Ala Pro Gly Glu Thr Val Rey et al., 2016
aprataxin and PNK-like factor Q8IW19 1-511 peptide-Ala17+Leu-peptide N Pro Arg Val Ala Leu Ala Pro Gly Rey et al., 2016
aprataxin and PNK-like factor Q8IW19 1-511 peptide-Pro29+Leu-peptide N Gly Arg Gly Pro Leu Leu Gly Ile Rey et al., 2016
aprataxin and PNK-like factor Q8IW19 1-511 peptide-Leu45+Glu-peptide N His Ala Ile Leu Glu Val Ala Gly Rey et al., 2016
aprataxin and PNK-like factor Q8IW19 1-511 peptide-Glu46+Val-peptide N Ala Ile Leu Glu Val Ala Gly Gly Rey et al., 2016
aprataxin and PNK-like factor Q8IW19 1-511 peptide-Ala48+Gly-peptide N Leu Glu Val Ala Gly Gly Gln Leu Rey et al., 2016
aprataxin and PNK-like factor Q8IW19 1-511 peptide-Pro56+Ile-peptide N Arg Ile Lys Pro Ile His Thr Asn Rey et al., 2016
aprataxin and PNK-like factor Q8IW19 1-511 peptide-Pro61+Cys-peptide N His Thr Asn Pro Cys Phe Tyr Gln Rey et al., 2016
aprataxin and PNK-like factor Q8IW19 1-511 peptide-Pro74+Leu-peptide N Gln Leu Leu Pro Leu Lys Pro Asn Rey et al., 2016
aprataxin and PNK-like factor Q8IW19 1-511 peptide-Pro77+Asn-peptide N Pro Leu Lys Pro Asn Leu Trp Cys Rey et al., 2016
aprataxin and PNK-like factor Q8IW19 1-511 peptide-Leu91+Leu-peptide N Ser Phe Ser Leu Leu Val Asp Lys Rey et al., 2016
aprataxin and PNK-like factor Q8IW19 1-511 peptide-Leu92+Val-peptide N Phe Ser Leu Leu Val Asp Lys Tyr Rey et al., 2016
aprataxin and PNK-like factor Q8IW19 1-511 peptide-Pro104+Ser-peptide N Leu Ser Ile Pro Ser Glu Val Glu Rey et al., 2016
aprataxin and PNK-like factor Q8IW19 1-511 peptide-Ser105+Glu-peptide N Ser Ile Pro Ser Glu Val Glu Met Rey et al., 2016
aprataxin and PNK-like factor Q8IW19 1-511 peptide-Pro129+Lys-peptide N Asn Glu Thr Pro Lys Ser Pro Val Rey et al., 2016
aprataxin and PNK-like factor Q8IW19 1-511 peptide-Pro132+Val-peptide N Pro Lys Ser Pro Val Ile Asn Leu Rey et al., 2016
aprataxin and PNK-like factor Q8IW19 1-511 peptide-Pro137+His-peptide N Ile Asn Leu Pro His Glu Thr Thr Rey et al., 2016
aprataxin and PNK-like factor Q8IW19 1-511 peptide-Ser149+Thr-peptide N Leu Glu Gly Ser Thr Glu Ile Ala Rey et al., 2016
aprataxin and PNK-like factor Q8IW19 1-511 peptide-Ala153+Lys-peptide N Thr Glu Ile Ala Lys Thr Gln Met Rey et al., 2016
aprataxin and PNK-like factor Q8IW19 1-511 peptide-Thr155+Gln-peptide N Ile Ala Lys Thr Gln Met Thr Pro Rey et al., 2016
aprataxin and PNK-like factor Q8IW19 1-511 peptide-Gln156+Met-peptide N Ala Lys Thr Gln Met Thr Pro Thr Rey et al., 2016
aprataxin and PNK-like factor Q8IW19 1-511 peptide-Pro159+Thr-peptide N Gln Met Thr Pro Thr Asn Ser Val Rey et al., 2016
aprataxin and PNK-like factor Q8IW19 1-511 peptide-Phe165+Leu-peptide N Ser Val Ser Phe Leu Gly Glu Asn Rey et al., 2016
aprataxin and PNK-like factor Q8IW19 1-511 peptide-Pro177+Ile-peptide N Lys Gln Gln Pro Ile Leu Ala Glu Rey et al., 2016
aprataxin and PNK-like factor Q8IW19 1-511 peptide-Leu179+Ala-peptide N Gln Pro Ile Leu Ala Glu Arg Lys Rey et al., 2016
aprataxin and PNK-like factor Q8IW19 1-511 peptide-Pro187+Thr-peptide N Arg Ile Leu Pro Thr Trp Met Leu Rey et al., 2016
aprataxin and PNK-like factor Q8IW19 1-511 peptide-Thr188+Trp-peptide N Ile Leu Pro Thr Trp Met Leu Ala Rey et al., 2016
aprataxin and PNK-like factor Q8IW19 1-511 peptide-Met190+Leu-peptide N Pro Thr Trp Met Leu Ala Glu His Rey et al., 2016
aprataxin and PNK-like factor Q8IW19 1-511 peptide-Ala192+Glu-peptide N Trp Met Leu Ala Glu His Leu Ser Rey et al., 2016
aprataxin and PNK-like factor Q8IW19 1-511 peptide-Pro203+Ala-peptide N Leu Ser Val Pro Ala Ile Ser Gly Rey et al., 2016
aprataxin and PNK-like factor Q8IW19 1-511 peptide-Ala204+Ile-peptide N Ser Val Pro Ala Ile Ser Gly Gly Rey et al., 2016
aprataxin and PNK-like factor Q8IW19 1-511 peptide-Glu218+Ile-peptide N Gly Lys Glu Glu Ile Cys Lys Asp Rey et al., 2016
aprataxin and PNK-like factor Q8IW19 1-511 peptide-Lys221+Asp-peptide N Glu Ile Cys Lys Asp Lys Ser Gln Rey et al., 2016
aprataxin and PNK-like factor Q8IW19 1-511 peptide-Lys223+Ser-peptide N Cys Lys Asp Lys Ser Gln Leu Asn Rey et al., 2016
aprataxin and PNK-like factor Q8IW19 1-511 peptide-Leu226+Asn-peptide N Lys Ser Gln Leu Asn Thr Thr Gln Rey et al., 2016
aprataxin and PNK-like factor Q8IW19 1-511 peptide-Arg233+Arg-peptide N Gln Gln Gly Arg Arg Gln Leu Ile Rey et al., 2016
aprataxin and PNK-like factor Q8IW19 1-511 peptide-Gln235+Leu-peptide N Gly Arg Arg Gln Leu Ile Ser Ser Rey et al., 2016
aprataxin and PNK-like factor Q8IW19 1-511 peptide-Leu236+Ile-peptide N Arg Arg Gln Leu Ile Ser Ser Gly Rey et al., 2016
aprataxin and PNK-like factor Q8IW19 1-511 peptide-Ala247+Glu-peptide N Asn Thr Ser Ala Glu Gln Asp Thr Rey et al., 2016
aprataxin and PNK-like factor Q8IW19 1-511 peptide-Pro271+Gln-peptide N Lys Glu Met Pro Gln Ser Phe Ser Rey et al., 2016
aprataxin and PNK-like factor Q8IW19 1-511 peptide-Ser273+Phe-peptide N Met Pro Gln Ser Phe Ser Ala Ile Rey et al., 2016
aprataxin and PNK-like factor Q8IW19 1-511 peptide-Ile277+Thr-peptide N Phe Ser Ala Ile Thr Leu Ser Asn Rey et al., 2016
aprataxin and PNK-like factor Q8IW19 1-511 peptide-Pro297+Ile-peptide N Asn Lys Leu Pro Ile Glu Glu Leu Rey et al., 2016
aprataxin and PNK-like factor Q8IW19 1-511 peptide-Glu300+Leu-peptide N Pro Ile Glu Glu Leu Gly Lys Val Rey et al., 2016
aprataxin and PNK-like factor Q8IW19 1-511 peptide-Ala310+Thr-peptide N His Lys Ile Ala Thr Lys Arg Thr Rey et al., 2016
aprataxin and PNK-like factor Q8IW19 1-511 peptide-Thr311+Lys-peptide N Lys Ile Ala Thr Lys Arg Thr Pro Rey et al., 2016
aprataxin and PNK-like factor Q8IW19 1-511 peptide-Pro315+His-peptide N Lys Arg Thr Pro His Lys Glu Asp Rey et al., 2016
aprataxin and PNK-like factor Q8IW19 1-511 peptide-Ala321+Met-peptide N Glu Asp Glu Ala Met Ser Cys Ser Rey et al., 2016
aprataxin and PNK-like factor Q8IW19 1-511 peptide-Pro351+Ser-peptide N Ser Ser Asn Pro Ser Asn Pro Glu Rey et al., 2016
aprataxin and PNK-like factor Q8IW19 1-511 peptide-Pro354+Glu-peptide N Pro Ser Asn Pro Glu Thr Leu His Rey et al., 2016
aprataxin and PNK-like factor Q8IW19 1-511 peptide-Thr356+Leu-peptide N Asn Pro Glu Thr Leu His Ala Lys Rey et al., 2016
aprataxin and PNK-like factor Q8IW19 1-511 peptide-Ala361+Thr-peptide N His Ala Lys Ala Thr Asp Ser Val Rey et al., 2016
aprataxin and PNK-like factor Q8IW19 1-511 peptide-Ser378+Cys-peptide N Lys Arg Thr Ser Cys Met Tyr Gly Rey et al., 2016
aprataxin and PNK-like factor Q8IW19 1-511 peptide-Met380+Tyr-peptide N Thr Ser Cys Met Tyr Gly Ala Asn Rey et al., 2016
aprataxin and PNK-like factor Q8IW19 1-511 peptide-Ala383+Asn-peptide N Met Tyr Gly Ala Asn Cys Tyr Arg Rey et al., 2016
aprataxin and PNK-like factor Q8IW19 1-511 peptide-Cys385+Tyr-peptide N Gly Ala Asn Cys Tyr Arg Lys Asn Rey et al., 2016
aprataxin and PNK-like factor Q8IW19 1-511 peptide-Pro390+Val-peptide N Arg Lys Asn Pro Val His Phe Gln Rey et al., 2016
aprataxin and PNK-like factor Q8IW19 1-511 peptide-Pro419+Glu-peptide N Asp Asp Arg Pro Glu Cys Pro Tyr Rey et al., 2016
aprataxin and PNK-like factor Q8IW19 1-511 peptide-Pro422+Tyr-peptide N Pro Glu Cys Pro Tyr Gly Pro Ser Rey et al., 2016
aprataxin and PNK-like factor Q8IW19 1-511 peptide-Pro425+Ser-peptide N Pro Tyr Gly Pro Ser Cys Tyr Arg Rey et al., 2016
aprataxin and PNK-like factor Q8IW19 1-511 peptide-Cys427+Tyr-peptide N Gly Pro Ser Cys Tyr Arg Lys Asn Rey et al., 2016
aprataxin and PNK-like factor Q8IW19 1-511 peptide-Lys430+Asn-peptide N Cys Tyr Arg Lys Asn Pro Gln His Rey et al., 2016
aprataxin and PNK-like factor Q8IW19 1-511 peptide-Glu437+Tyr-peptide N His Lys Ile Glu Tyr Arg His Asn Rey et al., 2016
aprataxin and PNK-like factor Q8IW19 1-511 peptide-Tyr438+Arg-peptide N Lys Ile Glu Tyr Arg His Asn Thr Rey et al., 2016
aprataxin and PNK-like factor Q8IW19 1-511 peptide-Arg439+His-peptide N Ile Glu Tyr Arg His Asn Thr Leu Rey et al., 2016
aprataxin and PNK-like factor Q8IW19 1-511 peptide-Thr442+Leu-peptide N Arg His Asn Thr Leu Pro Val Arg Rey et al., 2016
aprataxin and PNK-like factor Q8IW19 1-511 peptide-Leu443+Pro-peptide N His Asn Thr Leu Pro Val Arg Asn Rey et al., 2016
aprataxin and PNK-like factor Q8IW19 1-511 peptide-Pro444+Val-peptide N Asn Thr Leu Pro Val Arg Asn Val Rey et al., 2016
aprataxin and PNK-like factor Q8IW19 1-511 peptide-Pro459+Asn-peptide N Val Gly Gln Pro Asn Glu Tyr Asp Rey et al., 2016
aprataxin and PNK-like factor Q8IW19 1-511 peptide-Glu477+Pro-peptide N Glu Asp Tyr Glu Pro Thr Asp Glu Rey et al., 2016

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