Substrates for peptidase S9G.093: MSP 1 endopeptidase (Bothrops moojeni)

Summary Distribution Literature Substrates

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are thought to be pathologically relevant are indicated by D. Peptide and protein substrates that are not physiologically relevant are indicated by N. Synthetic substrates are indicated by S. Click on the symbol to show only physiological, non-physiological or synthetic substrates, or here to display all substrates. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a protein substrate, click on the UniProt Accession.

Substrate	Uniprot	Residue range	Cleavage Site	Cleavage type	P4	P3	P2	P1	P1'	P2'	P3'	P4'	Reference
Ac-Phe-Arg-NHPhNO2			Ac-Phe-Arg+NHPhNO2	S	-	Ac	Phe	Arg	NAN	-	-	-	Serrano et al., 1993
D-Phe-Pip-Arg-NHPhNO2			D-Phe-Pip-Arg+NHPhNO2	S	-	DPh	Pip	Arg	NAN	-	-	-	Serrano et al., 1993
D-Pro-Phe-Arg-NHPhNO2			D-Pro-Phe-Arg+NHPhNO2	S	-	DPr	Phe	Arg	NAN	-	-	-	Serrano et al., 1993
D-Val-Leu-Arg-NHPhNO2			D-Val-Leu-Arg+NHPhNO2	S	-	DVa	Leu	Arg	NAN	-	-	-	Serrano et al., 1993
D-Val-Leu-Lys-NHPhNO2			D-Val-Leu-Lys+NHPhNO2	S	-	DVa	Leu	Lys	NAN	-	-	-	Serrano et al., 1993
Insulin B chain (oxidised)	P01317	25-54	Phe-Val-Asn-Gln-His-Leu-Cya-Gly-Ser-His-Leu-Val-Glu-Ala-Leu-Tyr-Leu-Val-Cya-Gly-Glu-Arg+Gly-Phe-Phe-Tyr-Thr-Pro-Lys-Ala	N	Cya	Gly	Glu	Arg	Gly	Phe	Phe	Tyr	Reichl et al., 1993
Insulin B chain (oxidised)	P01317	25-54	Phe-Val-Asn-Gln-His-Leu-Cya-Gly-Ser-His-Leu-Val-Glu-Ala-Leu-Tyr-Leu-Val-Cya-Gly-Glu-Arg-Gly-Phe-Phe-Tyr-Thr-Pro-Lys+Ala	N	Tyr	Thr	Pro	Lys	Ala	-	-	-	Reichl et al., 1993
Tos-Arg-OMe			Tos-Arg+OMe	S	-	-	Tos	Arg	OMe	-	-	-	Serrano et al., 1993