Substrates for peptidase S54.004: AarA peptidase
Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are thought to be pathologically relevant are indicated by D. Peptide and protein substrates that are not physiologically relevant are indicated by N. Synthetic substrates are indicated by S. Click on the symbol to show only physiological, non-physiological or synthetic substrates, or here to display all substrates. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a protein substrate, click on the UniProt Accession.
| Substrate | Uniprot | Residue range | Cleavage Site | Cleavage type | Evidence | P4 | P3 | P2 | P1 | P1' | P2' | P3' | P4' | Reference | CutDB | MERNUM |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| hypothetical protein PROSTU_00642 | B2PVR5 | 1-97 | peptide-Ala8+Ala-peptide | P | Ile | Ala | Thr | Ala | Ala | Phe | Gly | Ser | Stevenson et al., 2007 | 21188 | ||
| lactose permease | P02920 | 39-74 | peptide-Ser43+Asp-peptide | N | Ile | Ser | Lys | Ser | Asp | Thr | Gly | Ile | Strisovsky et al., 2009 | |||
| protein gurken | P42287 | 239-288 | peptide-Ala246+His-peptide | N | Val | Arg | Met | Ala | His | Ile | Val | Phe | Strisovsky et al., 2009 | |||
| protein spitz | Q01083 | 131-181 | peptide-Ala142+Ser-peptide | N | Leu | Glu | Lys | Ala | Ser | Ile | Ala | Ser | Strisovsky et al., 2009 | |||
| tatA | A1YH68 | 1-50 | peptide-Ala8+Ala-peptide | P | NT | Ile | Ala | Thr | Ala | Ala | Phe | Gly | Ser | Strisovsky et al., 2009 | ||
| tatA (Ala6Arg mutant) | A1YH68 | 1-50 | peptide-Ala8+Ala-peptide | S | Ile | Arg | Thr | Ala | Ala | Phe | Gly | Ser | Strisovsky et al., 2009 | |||
| tatA (Ala6Asn mutant) | A1YH68 | 1-50 | peptide-Ala8+Ala-peptide | S | Ile | Asn | Thr | Ala | Ala | Phe | Gly | Ser | Strisovsky et al., 2009 | |||
| tatA (Ala6Gln mutant) | A1YH68 | 1-50 | peptide-Ala8+Ala-peptide | S | Ile | Gln | Thr | Ala | Ala | Phe | Gly | Ser | Strisovsky et al., 2009 | |||
| tatA (Ala6His mutant) | A1YH68 | 1-50 | peptide-Ala8+Ala-peptide | S | Ile | His | Thr | Ala | Ala | Phe | Gly | Ser | Strisovsky et al., 2009 | |||
| tatA (Ala6Ile mutant) | A1YH68 | 1-50 | peptide-Ala8+Ala-peptide | S | Ile | Ile | Thr | Ala | Ala | Phe | Gly | Ser | Strisovsky et al., 2009 | |||
| tatA (Ala6Leu mutant) | A1YH68 | 1-50 | peptide-Ala8+Ala-peptide | S | Ile | Leu | Thr | Ala | Ala | Phe | Gly | Ser | Strisovsky et al., 2009 | |||
| tatA (Ala6Lys mutant) | A1YH68 | 1-50 | peptide-Ala8+Ala-peptide | S | Ile | Lys | Thr | Ala | Ala | Phe | Gly | Ser | Strisovsky et al., 2009 | |||
| tatA (Ala6Met mutant) | A1YH68 | 1-50 | peptide-Ala8+Ala-peptide | S | Ile | Met | Thr | Ala | Ala | Phe | Gly | Ser | Strisovsky et al., 2009 | |||
| tatA (Ala6Ser mutant) | A1YH68 | 1-50 | peptide-Ala8+Ala-peptide | S | Ile | Ser | Thr | Ala | Ala | Phe | Gly | Ser | Strisovsky et al., 2009 | |||
| tatA (Ala6Thr mutant) | A1YH68 | 1-50 | peptide-Ala8+Ala-peptide | S | Ile | Thr | Thr | Ala | Ala | Phe | Gly | Ser | Strisovsky et al., 2009 | |||
| tatA (Ala6Tyr mutant) | A1YH68 | 1-50 | peptide-Ala8+Ala-peptide | S | Ile | Tyr | Thr | Ala | Ala | Phe | Gly | Ser | Strisovsky et al., 2009 | |||
| tatA (Ala6Val mutant) | A1YH68 | 1-50 | peptide-Ala8+Ala-peptide | S | Ile | Val | Thr | Ala | Ala | Phe | Gly | Ser | Strisovsky et al., 2009 | |||
| tatA (Ala8Cys mutant) | A1YH68 | 1-50 | peptide-Ala8+Ala-peptide | S | Ile | Ala | Thr | Cys | Ala | Phe | Gly | Ser | Strisovsky et al., 2009 | |||
| tatA (Ala9Asn mutant) | A1YH68 | 1-50 | peptide-Ala8+Gly-peptide | S | Ile | Ala | Thr | Ala | Asn | Phe | Gly | Ser | Strisovsky et al., 2009 | |||
| tatA (Ala9Cys mutant) | A1YH68 | 1-50 | peptide-Ala8+Gly-peptide | S | Ile | Ala | Thr | Ala | Cys | Phe | Gly | Ser | Strisovsky et al., 2009 | |||
| tatA (Ala9Gln mutant) | A1YH68 | 1-50 | peptide-Ala8+Gly-peptide | S | Ile | Ala | Thr | Ala | Gln | Phe | Gly | Ser | Strisovsky et al., 2009 | |||
| tatA (Ala9Glu mutant) | A1YH68 | 1-50 | peptide-Ala8+Gly-peptide | S | Ile | Ala | Thr | Ala | Glu | Phe | Gly | Ser | Strisovsky et al., 2009 | |||
| tatA (Ala9Gly mutant) | A1YH68 | 1-50 | peptide-Ala8+Gly-peptide | S | Ile | Ala | Thr | Ala | Gly | Phe | Gly | Ser | Strisovsky et al., 2009 | |||
| tatA (Ala9Lys mutant) | A1YH68 | 1-50 | peptide-Ala8+Gly-peptide | S | Ile | Ala | Thr | Ala | Lys | Phe | Gly | Ser | Strisovsky et al., 2009 | |||
| tatA (Ala9Met mutant) | A1YH68 | 1-50 | peptide-Ala8+Gly-peptide | S | Ile | Ala | Thr | Ala | Met | Phe | Gly | Ser | Strisovsky et al., 2009 | |||
| tatA (Ala9Ser mutant) | A1YH68 | 1-50 | peptide-Ala8+Gly-peptide | S | Ile | Ala | Thr | Ala | Ser | Phe | Gly | Ser | Strisovsky et al., 2009 | |||
| tatA (Ala9Thr mutant) | A1YH68 | 1-50 | peptide-Ala8+Gly-peptide | S | Ile | Ala | Thr | Ala | Thr | Phe | Gly | Ser | Strisovsky et al., 2009 | |||
| tatA (Ile5Met mutant) | A1YH68 | 1-50 | peptide-Ala8+Ala-peptide | S | Met | Ala | Thr | Ala | Ala | Phe | Gly | Ser | Strisovsky et al., 2009 | |||
| tatA (Ile5Tyr mutant) | A1YH68 | 1-50 | peptide-Ala8+Ala-peptide | S | Tyr | Ala | Thr | Ala | Ala | Phe | Gly | Ser | Strisovsky et al., 2009 | |||
| tatA (Phe10Ala mutant) | A1YH68 | 1-50 | peptide-Ala8+Ala-peptide | S | Ile | Ala | Thr | Ala | Ala | Ala | Gly | Ser | Strisovsky et al., 2009 | |||
| tatA (Phe10Cys mutant) | A1YH68 | 1-50 | peptide-Ala8+Ala-peptide | S | Ile | Ala | Thr | Ala | Ala | Cys | Gly | Ser | Strisovsky et al., 2009 | |||
| tatA (Phe10Ile mutant) | A1YH68 | 1-50 | peptide-Ala8+Ala-peptide | S | Ile | Ala | Thr | Ala | Ala | Ile | Gly | Ser | Strisovsky et al., 2009 | |||
| tatA (Phe10Met mutant) | A1YH68 | 1-50 | peptide-Ala8+Ala-peptide | S | Ile | Ala | Thr | Ala | Ala | Met | Gly | Ser | Strisovsky et al., 2009 | |||
| tatA (Phe10Val mutant) | A1YH68 | 1-50 | peptide-Ala8+Ala-peptide | S | Ile | Ala | Thr | Ala | Ala | Val | Gly | Ser | Strisovsky et al., 2009 | |||
| tatA (Thr4Arg mutant) | A1YH68 | 1-50 | peptide-Ala8+Ala-peptide | S | Ile | Ala | Thr | Ala | Ala | Phe | Gly | Ser | Strisovsky et al., 2009 | |||
| tatA (Thr4Asn mutant) | A1YH68 | 1-50 | peptide-Ala8+Ala-peptide | S | Ile | Ala | Thr | Ala | Ala | Phe | Gly | Ser | Strisovsky et al., 2009 | |||
| tatA (Thr4Gln mutant) | A1YH68 | 1-50 | peptide-Ala8+Ala-peptide | S | Ile | Ala | Thr | Ala | Ala | Phe | Gly | Ser | Strisovsky et al., 2009 | |||
| tatA (Thr4His mutant) | A1YH68 | 1-50 | peptide-Ala8+Ala-peptide | S | Ile | Ala | Thr | Ala | Ala | Phe | Gly | Ser | Strisovsky et al., 2009 | |||
| tatA (Thr4Ile mutant) | A1YH68 | 1-50 | peptide-Ala8+Ala-peptide | S | Ile | Ala | Thr | Ala | Ala | Phe | Gly | Ser | Strisovsky et al., 2009 | |||
| tatA (Thr4Leu mutant) | A1YH68 | 1-50 | peptide-Ala8+Ala-peptide | S | Ile | Ala | Thr | Ala | Ala | Phe | Gly | Ser | Strisovsky et al., 2009 | |||
| tatA (Thr4Lys mutant) | A1YH68 | 1-50 | peptide-Ala8+Ala-peptide | S | Ile | Ala | Thr | Ala | Ala | Phe | Gly | Ser | Strisovsky et al., 2009 | |||
| tatA (Thr4Met mutant) | A1YH68 | 1-50 | peptide-Ala8+Ala-peptide | S | Ile | Ala | Thr | Ala | Ala | Phe | Gly | Ser | Strisovsky et al., 2009 | |||
| tatA (Thr4Ser mutant) | A1YH68 | 1-50 | peptide-Ala8+Ala-peptide | S | Ile | Ala | Thr | Ala | Ala | Phe | Gly | Ser | Strisovsky et al., 2009 | |||
| tatA (Thr4Tyr mutant) | A1YH68 | 1-50 | peptide-Ala8+Ala-peptide | S | Ile | Ala | Thr | Ala | Ala | Phe | Gly | Ser | Strisovsky et al., 2009 | |||
| tatA (Thr4Val mutant) | A1YH68 | 1-50 | peptide-Ala8+Ala-peptide | S | Ile | Ala | Thr | Ala | Ala | Phe | Gly | Ser | Strisovsky et al., 2009 | |||
| tatA (Thr7Ala mutant) | A1YH68 | 1-50 | peptide-Ala8+Ala-peptide | S | Ile | Ala | Ala | Ala | Ala | Phe | Gly | Ser | Strisovsky et al., 2009 | |||
| tatA (Thr7Arg mutant) | A1YH68 | 1-50 | peptide-Ala8+Ala-peptide | S | Ile | Ala | Arg | Ala | Ala | Phe | Gly | Ser | Strisovsky et al., 2009 | |||
| tatA (Thr7Asn mutant) | A1YH68 | 1-50 | peptide-Ala8+Ala-peptide | S | Ile | Ala | Asn | Ala | Ala | Phe | Gly | Ser | Strisovsky et al., 2009 | |||
| tatA (Thr7Cys mutant) | A1YH68 | 1-50 | peptide-Ala8+Ala-peptide | S | Ile | Ala | Cys | Ala | Ala | Phe | Gly | Ser | Strisovsky et al., 2009 | |||
| tatA (Thr7Gln mutant) | A1YH68 | 1-50 | peptide-Ala8+Ala-peptide | S | Ile | Ala | Gln | Ala | Ala | Phe | Gly | Ser | Strisovsky et al., 2009 | |||
| tatA (Thr7Glu mutant) | A1YH68 | 1-50 | peptide-Ala8+Ala-peptide | S | Ile | Ala | Glu | Ala | Ala | Phe | Gly | Ser | Strisovsky et al., 2009 | |||
| tatA (Thr7His mutant) | A1YH68 | 1-50 | peptide-Ala8+Ala-peptide | S | Ile | Ala | His | Ala | Ala | Phe | Gly | Ser | Strisovsky et al., 2009 | |||
| tatA (Thr7Leu mutant) | A1YH68 | 1-50 | peptide-Ala8+Ala-peptide | S | Ile | Ala | Leu | Ala | Ala | Phe | Gly | Ser | Strisovsky et al., 2009 | |||
| tatA (Thr7Lys mutant) | A1YH68 | 1-50 | peptide-Ala8+Ala-peptide | S | Ile | Ala | Lys | Ala | Ala | Phe | Gly | Ser | Strisovsky et al., 2009 | |||
| tatA (Thr7Met mutant) | A1YH68 | 1-50 | peptide-Ala8+Ala-peptide | S | Ile | Ala | Met | Ala | Ala | Phe | Gly | Ser | Strisovsky et al., 2009 | |||
| tatA (Thr7Pro mutant) | A1YH68 | 1-50 | peptide-Ala8+Ala-peptide | S | Ile | Ala | Pro | Ala | Ala | Phe | Gly | Ser | Strisovsky et al., 2009 | |||
| tatA (Thr7Ser mutant) | A1YH68 | 1-50 | peptide-Ala8+Ala-peptide | S | Ile | Ala | Ser | Ala | Ala | Phe | Gly | Ser | Strisovsky et al., 2009 | |||
| tatA (Thr7Val mutant) | A1YH68 | 1-50 | peptide-Ala8+Ala-peptide | S | Ile | Ala | Val | Ala | Ala | Phe | Gly | Ser | Strisovsky et al., 2009 |
