Substrates for peptidase S53.011: scytalidolisin

Summary Alignment Sequences Sequence features Distribution Literature Substrates

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are thought to be pathologically relevant are indicated by D. Peptide and protein substrates that are not physiologically relevant are indicated by N. Synthetic substrates are indicated by S. Click on the symbol to show only physiological, non-physiological or synthetic substrates, or here to display all substrates. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a protein substrate, click on the UniProt Accession.

Substrate	Uniprot	Residue range	Cleavage Site	Cleavage type	P4	P3	P2	P1	P1'	P2'	P3'	P4'	Reference
insulin B-chain (oxidized)	P01317	25-54	Phe-Val-Asn-Gln-His-Leu-Cya-Gly-Ser-His-Leu-Val-Glu-Ala-Leu-Tyr-Leu-Val-Cya+Gly-Glu-Arg-Gly-Phe-Phe-Tyr-Thr-Pro-Lys-Ala	N	Tyr	Leu	Val	Cya	Gly	Glu	Arg	Gly	Murao, 2004
insulin B-chain (oxidized)	P01317	25-54	Phe-Val-Asn-Gln-His-Leu-Cya-Gly-Ser-His-Leu-Val-Glu-Ala-Leu-Tyr-Leu-Val-Cya-Gly-Glu-Arg-Gly-Phe+Phe-Tyr-Thr-Pro-Lys-Ala	N	Glu	Arg	Gly	Phe	Phe	Tyr	Thr	Pro	Murao, 2004
Z-Ala-Ala-Lys-Ala-Ala-Ala			Z-Ala-Ala-Lys+Ala-Ala-Ala	S	Z	Ala	Ala	Lys	Ala	Ala	Ala	-	Morihara et al., 1979
Z-Ala-Leu-Ala-Ala			Z-Ala-Leu+Ala-Ala	S	-	Z	Ala	Leu	Ala	Ala	-	-	Morihara et al., 1979
Z-Ala-Lys-Ala-Ala-Ala			Z-Ala-Lys+Ala-Ala-Ala	S	-	Z	Ala	Lys	Ala	Ala	Ala	-	Morihara et al., 1979
Z-Ala-Phe-Gly-Ala			Z-Ala-Phe+Gly-Ala	S	-	Z	Ala	Phe	Gly	Ala	-	-	Morihara et al., 1979
Z-Ala-Phe-Leu-Ala			Z-Ala-Phe+Leu-Ala	S	-	Z	Ala	Phe	Leu	Ala	-	-	Morihara et al., 1979
Z-Gly-Leu-Ala-Ala			Z-Gly-Leu+Ala-Ala	S	-	Z	Gly	Leu	Ala	Ala	-	-	Morihara et al., 1979
Z-Gly-Leu-Gly-Ala			Z-Gly-Leu+Gly-Ala	S	-	Z	Gly	Leu	Gly	Ala	-	-	Morihara et al., 1979
Z-Gly-Leu-Gly-Gly			Z-Gly-Leu+Gly-Gly	S	-	Z	Gly	Leu	Gly	Gly	-	-	Morihara et al., 1979
Z-Gly-Leu-Gly-Phe			Z-Gly-Leu+Gly-Phe	S	-	Z	Gly	Leu	Gly	Phe	-	-	Morihara et al., 1979
Z-Gly-Phe-Leu-Ala			Z-Gly-Phe+Leu-Ala	S	-	Z	Gly	Phe	Leu	Ala	-	-	Morihara et al., 1979
Z-Lys-Ala-Ala-Ala			Z-Lys-Ala+Ala-Ala	S	-	Z	Lys	Ala	Ala	Ala	-	-	Morihara et al., 1979
Z-Lys-Ala-Ala-Ala-Ala			Z-Lys-Ala+Ala-Ala-Ala	S	-	Z	Lys	Ala	Ala	Ala	Ala	-	Morihara et al., 1979
Z-Lys-Leu-Ala-Ala			Z-Lys-Leu+Ala-Ala	S	-	Z	Lys	Leu	Ala	Ala	-	-	Morihara et al., 1979
Z-Phe-Ala-Ala-Ala			Z-Phe-Ala+Ala-Ala	S	-	Z	Phe	Ala	Ala	Ala	-	-	Morihara et al., 1979
Z-Phe-Glu-Ala-Ala			Z-Phe-Glu+Ala-Ala	S	-	Z	Phe	Glu	Ala	Ala	-	-	Morihara et al., 1979
Z-Phe-Leu-Ala-Ala			Z-Phe-Leu+Ala-Ala	S	-	Z	Phe	Leu	Ala	Ala	-	-	Morihara et al., 1979
Z-Phe-Lys-Ala-Ala			Z-Phe-Lys+Ala-Ala	S	-	Z	Phe	Lys	Ala	Ala	-	-	Morihara et al., 1979
Z-Phe-Tyr-Ala-Ala			Z-Phe-Tyr+Ala-Ala	S	-	Z	Phe	Tyr	Ala	Ala	-	-	Morihara et al., 1979