Substrates for peptidase S50.001: infectious pancreatic necrosis birnavirus Vp4 peptidase

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are thought to be pathologically relevant are indicated by D. Peptide and protein substrates that are not physiologically relevant are indicated by N. Synthetic substrates are indicated by S. Click on the symbol to show only physiological, non-physiological or synthetic substrates, or here to display all substrates. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a protein substrate, click on the UniProt Accession.

Substrate	Uniprot	Residue range	Cleavage Site	Cleavage type	Evidence	P4	P3	P2	P1	P1'	P2'	P3'	P4'	Reference	CutDB
structural polyprotein	P15480	1-1012	peptide-Arg453+Lys-peptide	P		Arg	Ala	Ile	Arg	Arg	Ile	Ala	Val		17765
structural polyprotein	P15480	1-1012	peptide-Lys722+Arg-peptide	P		Thr	Phe	Ile	Lys	Arg	Phe	Pro	His		17766
Structural polyprotein	Q703G9	494-972	Peptide-Ala734+Ser-Peptide	P	NT	Ala	Ser	Asn	Ala	Ser	Gly	Met	Asp	Petit et al., 2000
Structural polyprotein	Q703G9	1-972	Peptide-Ala495+Ala-Peptide	P	NT	His	Ser	Met	Ala	Ala	Gly	Gly	Arg	Galloux et al., 2004
Structural polyprotein	Q703G9	1-972	Peptide-Ala442+Try-Peptide	P	NT	Thr	Ser	Lys	Ala	Trp	Gly	Trp	Arg	Galloux et al., 2004
Structural polyprotein	Q703G9	1-972	Peptide-Ala486+Ala-Peptide	P	NT	Lys	Thr	Asn	Ala	Ala	Gly	Gly	Arg	Galloux et al., 2004
Structural polyprotein	Q703G9	1-972	Peptide-Ala508+Ser-Peptide	P	NT	Glu	Ser	Trp	Ala	Ser	Gly	Gly	Pro	Galloux et al., 2004
Structural polyprotein	Q703G9	494-972	Peptide-Arg715+Ala-Peptide	P	NT	Pro	Val	Gln	Arg	Ala	Lys	Gly	Ser	Petit et al., 2000