Substrates for peptidase S33.010: SCO7095-type peptidase

Summary Alignment Tree Sequences Sequence features Distribution Literature Substrates

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are thought to be pathologically relevant are indicated by D. Peptide and protein substrates that are not physiologically relevant are indicated by N. Synthetic substrates are indicated by S. Click on the symbol to show only physiological, non-physiological or synthetic substrates, or here to display all substrates. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a protein substrate, click on the UniProt Accession.

Substrate	Cleavage Site	Cleavage type	P4	P3	P2	P1	P1'	P2'	P3'	P4'	Reference
Ala-Ala-Phe-NHMec	Ala-Ala-Phe-NHMec	S	-	Ala	Ala	Phe	AMC	-	-	-	Nagy et al., 2003
Ala-Arg-NHMec	Ala-Arg-NHMec	S	-	-	Ala	Arg	AMC	-	-	-	Nagy et al., 2003
Boc-Leu-Arg-Arg-NHMec	Boc-Leu-Arg-Arg-NHMec	S	Boc	Leu	Arg	Arg	AMC	-	-	-	Nagy et al., 2003
Boc-Val-Pro-Arg-NHMec	Boc-Val-Pro-Arg-NHMec	S	Boc	Val	Pro	Arg	AMC	-	-	-	Nagy et al., 2003
Pro-Arg-NHMec	Pro-Arg-NHMec	S	-	-	Pro	Arg	AMC	-	-	-	Nagy et al., 2003
Suc-Leu-Leu-Val-Tyr-NHMec	Suc-Leu-Leu-Val-Tyr-NHMec	S	Leu	Leu	Val	Tyr	AMC	-	-	-	Nagy et al., 2003
Suc-Leu-Tyr-NHMec	Suc-Leu-Tyr-NHMec	S	-	Suc	Leu	Tyr	AMC	-	-	-	Nagy et al., 2003
Z-Arg-Arg-NHMec	Z-Arg-Arg-NHMec	S	-	Z	Arg	Arg	AMC	-	-	-	Nagy et al., 2003
Z-Arg-NHMec	Z-Arg-NHMec	S	-	-	Z	Arg	AMC	-	-	-	Nagy et al., 2003
Z-Gly-Gly-Leu-NHMec	Z-Gly-Gly-Leu+NHMec	S	Z	Gly	Gly	Leu	AMC	-	-	-	Nagy et al., 2003
Z-Gly-Pro-Leu-NHMec	Z-Gly-Pro-Leu-NHMec	S	Z	Gly	Pro	Leu	AMC	-	-	-	Nagy et al., 2003