Substrates for peptidase S31.001: pestivirus NS3 polyprotein peptidase

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are thought to be pathologically relevant are indicated by D. Peptide and protein substrates that are not physiologically relevant are indicated by N. Synthetic substrates are indicated by S. Click on the symbol to show only physiological, non-physiological or synthetic substrates, or here to display all substrates. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a protein substrate, click on the UniProt Accession.

Substrate Uniprot Residue range Cleavage Site Cleavage type Evidence P4 P3 P2 P1 P1' P2' P3' P4' Reference CutDB MERNUM
genome polyprotein Q96662 1-3907 peptide-Leu2281+Ser-peptide N Val Val Gly Leu Ser Ser Ala Glu 17740
genome polyprotein Q96662 1-3907 peptide-Leu2345+Ala-peptide N Leu Lys Glu Leu Ala Val Gly Asp 17741
genome polyprotein Q96662 1-3907 peptide-Leu2692+Ser-peptide N Ile Arg Asn Leu Ser Gly Asn Tyr 17742
genome polyprotein Q96662 1-3907 peptide-Leu3188+Ser-peptide N Thr Met Lys Leu Ser Ser Trp Phe 17743