Substrates for peptidase S29.001: hepacivirin

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates Pharma

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are thought to be pathologically relevant are indicated by D. Peptide and protein substrates that are not physiologically relevant are indicated by N. Synthetic substrates are indicated by S. Click on the symbol to show only physiological, non-physiological or synthetic substrates, or here to display all substrates. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a protein substrate, click on the UniProt Accession.

Substrate	Uniprot	Residue range	Cleavage Site	Cleavage type	Evidence	P4	P3	P2	P1	P1'	P2'	P3'	P4'	Reference	CutDB
delta(24)-sterol reductase	Q15392	23-516	peptide-Cys91+Thr-peptide	P	NT	Thr	Phe	Met	Cys	Thr	Gly	Arg	Pro	Tallorin et al., 2020
hepacivirus polyprotein	P26664	2-3011	peptide-Thr1657+Ser-peptide	P		Glu	Val	Val	Thr	Ser	Thr	Trp	Val	Rice, 1998	17738
hepacivirus polyprotein	P26664	2-3011	peptide-Cys1711+Ser-peptide	P		Met	Glu	Glu	Cys	Ser	Gln	His	Leu	Rice, 1998	17735
hepacivirus polyprotein	P26664	2-3011	peptide-Cys1972+Ser-peptide	P		Thr	Thr	Pro	Cys	Ser	Gly	Ser	Trp	Rice, 1998	17736
hepacivirus polyprotein	P26664	2-3011	peptide-Cys2420+Ser-peptide	P		Val	Val	Cys	Cys	Ser	Met	Ser	Tyr	Rice, 1998	17737
oCIA domain-containing protein 1	Q9NX40	1-245	peptide-Cys38+Asn-peptide	P	NT	Phe	Ala	Glu	Cys	Asn	Asp	Glu	Ser	Tran et al., 2020