Substrates for peptidase S26.015: Streptococcus-type signal peptidase

Summary Alignment Tree Sequences Sequence features Distribution Literature Substrates

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are thought to be pathologically relevant are indicated by D. Peptide and protein substrates that are not physiologically relevant are indicated by N. Synthetic substrates are indicated by S. Click on the symbol to show only physiological, non-physiological or synthetic substrates, or here to display all substrates. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a protein substrate, click on the UniProt Accession.

Substrate	Uniprot	Residue range	Cleavage Site	Cleavage type	Evidence	P4	P3	P2	P1	P1'	P2'	P3'	P4'	Reference
signal peptidase I	O07344	1-204	peptide-Gly36+His-peptide	P	NT	Arg	Val	Glu	Gly	His	Ser	Met	Asp	Peng et al., 2001
Signal peptidase I	P59662	1-204	Peptide-Ala65+His-Peptide	P	NT	Ile	Val	Val	Ala	His	Glu	Glu	Asp	Zheng et al., 2002
Signal peptidase I	P59662	1-204	Peptide-Ala143+Phe-Peptide	P	NT	Lys	Ala	Gln	Ala	Phe	Thr	Val	Asp	Zheng et al., 2002
streptokinase A	P10520	1-440	peptide-Ala26+Ile-peptide	P	NT	Ser	Val	Gln	Ala	Ile	Ala	Gly	Tyr	Peng et al., 2001
Zinc metalloprotease ZmpB	Q9L7Q2	34-1906	peptide-Ala33+Ala-peptide	P	CS	Val	Val	Asp	Ala	Ala	Thr	Tyr	His	Berge et al., 2001
Zinc metalloprotease ZmpB	B5E2Q6	34-1870	peptide-Ala33+Ala-peptide	P	CS	Val	Val	Asp	Ala	Ala	Thr	Tyr	His	Berge et al., 2001