Substrates for peptidase S16.002: PIM1 peptidase

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are thought to be pathologically relevant are indicated by D. Peptide and protein substrates that are not physiologically relevant are indicated by N. Synthetic substrates are indicated by S. Click on the symbol to show only physiological, non-physiological or synthetic substrates, or here to display all substrates. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a protein substrate, click on the UniProt Accession.

Substrate	Uniprot	Residue range	Cleavage Site	Cleavage type	P4	P3	P2	P1	P1'	P2'	P3'	P4'	Reference
mitochondrial-processing peptidase alpha subunit, mitochondrial precursor	P11914	14-482	peptide-Cys60+Thr-peptide	N	Leu	Lys	Gly	Cys	Thr	His	Ile	Leu	Ondrovicova et al., 2005
mitochondrial-processing peptidase alpha subunit, mitochondrial precursor	P11914	14-482	peptide-Phe69+Lys-peptide	N	Arg	Leu	Ala	Phe	Lys	Ser	Thr	Glu	Ondrovicova et al., 2005
mitochondrial-processing peptidase alpha subunit, mitochondrial precursor	P11914	14-482	peptide-Leu386+Val-peptide	N	Glu	Ser	Lys	Leu	Val	Glu	Leu	Glu	Ondrovicova et al., 2005
mitochondrial-processing peptidase alpha subunit, mitochondrial precursor	P11914	14-482	peptide-Met398+His-peptide	N	Gln	Val	Leu	Met	His	Gly	Arg	Lys	Ondrovicova et al., 2005
steroidogenic acute regulatory protein, mitochondrial precursor	P51557	1-284	peptide-Leu246+Lys-peptide	N	Ser	Ile	Asp	Leu	Lys	Gly	Trp	Leu	Ondrovicova et al., 2005
steroidogenic acute regulatory protein, mitochondrial precursor	P51557	1-284	peptide-Leu259+Ser-peptide	N	Asn	Gln	Val	Leu	Ser	Gln	Thr	Gln	Ondrovicova et al., 2005
steroidogenic acute regulatory protein, mitochondrial precursor	P51557	1-284	peptide-Ala142+Met-peptide	N	Arg	Met	Glu	Ala	Met	Gly	Glu	Trp	Ondrovicova et al., 2005
steroidogenic acute regulatory protein, mitochondrial precursor	P51557	1-284	peptide-Leu156+Gln-peptide	N	Ile	Lys	Val	Leu	Gln	Arg	Ile	Gly	Ondrovicova et al., 2005