Substrates for peptidase S10.007: kex carboxypeptidase

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are thought to be pathologically relevant are indicated by D. Peptide and protein substrates that are not physiologically relevant are indicated by N. Synthetic substrates are indicated by S. Click on the symbol to show only physiological, non-physiological or synthetic substrates, or here to display all substrates. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a protein substrate, click on the UniProt Accession.

Substrate	Uniprot	Residue range	Cleavage Site	Cleavage type	P4	P3	P2	P1	P1'	P2'	P3'	P4'	Reference	CutDB
alpha-1 mating factor precursor	P01149	20-144	peptide-Tyr+Lys	P	Gln	Pro	Met	Tyr	Lys	-	-	-	Remington, 2004	17700
alpha-1 mating factor precursor	P01149	20-145	peptide-Lys+Arg	P	Pro	Met	Tyr	Lys	Arg	-	-	-	Remington, 2004	17699
Bz-Phe-Ala-Arg			Bz-Phe-Ala+Arg	S	-	Bz	Phe	Ala	Arg	-	-	-	Latchinian-Sadek & Thomas, 1993
FA-Ala-Arg			FA-Ala+Arg	S	-	-	FA	Ala	Arg	-	-	-	Latchinian-Sadek & Thomas, 1993
FA-Ala-Lys			FA-Ala+Lys	S	-	-	FA	Ala	Lys	-	-	-	Latchinian-Sadek & Thomas, 1993
[Leu]enkephalin-Arg			Tyr-Gly-Gly-Phe-Leu+Arg	S	Gly	Gly	Phe	Leu	Arg	-	-	-	Latchinian-Sadek & Thomas, 1993
[Leu]enkephalin-Lys			Tyr-Gly-Gly-Phe-Leu+Lys	S	Gly	Gly	Phe	Leu	Lys	-	-	-	Latchinian-Sadek & Thomas, 1993
[Met]enkephalin-Arg			Tyr-Gly-Gly-Phe-Met+Arg	S	Gly	Gly	Phe	Met	Arg	-	-	-	Latchinian-Sadek & Thomas, 1993
[Met]enkephalin-Lys			Tyr-Gly-Gly-Phe-Met+Lys	S	Gly	Gly	Phe	Met	Lys	-	-	-	Latchinian-Sadek & Thomas, 1993