Substrates for peptidase S09.075: dipeptidyl-peptidase 5 (Porphyromonas sp.)

Summary Alignment Tree Sequences Sequence features Distribution Literature Substrates

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are thought to be pathologically relevant are indicated by D. Peptide and protein substrates that are not physiologically relevant are indicated by N. Synthetic substrates are indicated by S. Click on the symbol to show only physiological, non-physiological or synthetic substrates, or here to display all substrates. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a protein substrate, click on the UniProt Accession.

Substrate Uniprot Residue range Cleavage Site Cleavage type Evidence P4 P3 P2 P1 P1' P2' P3' P4' Reference CutDB MERNUM
Gly-Phe-NHMec Gly-Phe+NHMec S - - Gly Phe AMC - - - Ohara-Nemoto et al., 2014
Lys-Ala-NHMec Lys-Ala+NHMec S - - Lys Ala AMC - - - Ohara-Nemoto et al., 2014
Lys-Leu-NHMec Lys-Leu+NHMec S - - Lys Leu AMC - - - Ohara-Nemoto et al., 2014
Lys-Phe-NHMec Lys-Phe+NHMec S - - Lys Phe AMC - - - Ohara-Nemoto et al., 2014
Lys-Val-NHMec Lys-Val+NHMec S - - Lys Val AMC - - - Ohara-Nemoto et al., 2014
Met-Leu-NHMec Met-Leu+NHMec S - - Met Leu AMC - - - Ohara-Nemoto et al., 2014
Ser-Tyr-NHMec Ser-Tyr+NHMec S - - Ser Tyr AMC - - - Ohara-Nemoto et al., 2014