Substrates for peptidase S09.069: omega peptidase (Drosophila melanogaster)

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Literature Substrates

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are thought to be pathologically relevant are indicated by D. Peptide and protein substrates that are not physiologically relevant are indicated by N. Synthetic substrates are indicated by S. Click on the symbol to show only physiological, non-physiological or synthetic substrates, or here to display all substrates. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a protein substrate, click on the UniProt Accession.

Substrate Uniprot Residue range Cleavage Site Cleavage type Evidence P4 P3 P2 P1 P1' P2' P3' P4' Reference CutDB MERNUM
Ala-Pro-NHPhNO2 Ala-Pro+NHPhNO2 S - - Ala Pro NAN - - - Hsieh et al., 2011
Glu-Ala-NHPhNO2 Glu-Ala+NHPhNO2 S - - Glu Ala NAN - - - Hsieh et al., 2011
Glu-Pro-NHPhNO2 Glu-Pro+NHPhNO2 S - - Glu Pro NAN - - - Hsieh et al., 2011
Gly-Pro-NHPhNO2 Gly-Pro+NHPhNO2 S - - Gly Pro NAN - - - Hsieh et al., 2011
Lys-Ala-NHPhNO2 Lys-Ala+NHPhNO2 S - - Lys Ala NAN - - - Hsieh et al., 2011
Lys-Pro-NHPhNO2 Lys-Pro+NHPhNO2 S - - Lys Pro NAN - - - Hsieh et al., 2011
prepromastoparan B Q0R4F6 23-60 Ala-Glu+Leu-peptide P CS - Ala Glu Ala Leu Ala Asp Pro Hsieh et al., 2011
prepromastoparan B Q0R4F6 25-60 Ala-Leu+Asp-peptide P CS - Ala Leu Ala Asp Pro Leu Ala Hsieh et al., 2011
prepromastoparan B Q0R4F6 27-60 Ala-Asp+Leu-peptide P CS - Ala Asp Pro Leu Ala Glu Pro Hsieh et al., 2011
prepromastoparan B Q0R4F6 29-60 Pro-Leu+Glu-peptide P CS - Pro Leu Ala Glu Pro Leu Ala Hsieh et al., 2011
prepromastoparan B Q0R4F6 31-60 Ala-Glu+Leu-peptide P CS - Ala Glu Pro Leu Ala Asp Pro Hsieh et al., 2011
prepromastoparan B Q0R4F6 33-60 Pro-Leu+Asp-peptide P CS - Pro Leu Ala Asp Pro Asn Ala Hsieh et al., 2011
prepromastoparan B Q0R4F6 35-60 Ala-Asp+Asn-peptide P CS - Ala Asp Pro Asn Ala Glu Ala Hsieh et al., 2011
prepromastoparan B Q0R4F6 37-60 Pro-Asn+Glu-peptide P CS - Pro Asn Ala Glu Ala Asp Pro Hsieh et al., 2011
prepromastoparan B Q0R4F6 39-60 Ala-Glu+Asp-peptide P CS - Ala Glu Ala Asp Pro Glu Ala Hsieh et al., 2011
prepromastoparan B Q0R4F6 41-60 Ala-Asp-Pro+Glu-Ala-Leu-Lys-Leu-Lys-Ser-Ile-Val-Ser-Trp-Ala-Lys-Lys-Val-Leu-Gly P CS - Ala Asp Pro Glu Ala Leu Lys Hsieh et al., 2011
prepromastoparan B Q0R4F6 43-60 Pro-Glu-Ala+Leu-Lys-Leu-Lys-Ser-Ile-Val-Ser-Trp-Ala-Lys-Lys-Val-Leu-Gly P CS - Pro Glu Ala Leu Lys Leu Lys Hsieh et al., 2011
Ser-Pro-NHPhNO2 Ser-Pro+NHPhNO2 S - - Ser Pro NAN - - - Hsieh et al., 2011