Substrates for peptidase S08.065: MutP (Streptococcus mutans)-type lantibiotic leader peptidase

Summary Alignment Sequences Sequence features Distribution Literature Substrates

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are thought to be pathologically relevant are indicated by D. Peptide and protein substrates that are not physiologically relevant are indicated by N. Synthetic substrates are indicated by S. Click on the symbol to show only physiological, non-physiological or synthetic substrates, or here to display all substrates. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a protein substrate, click on the UniProt Accession.

Substrate	Uniprot	Residue range	Cleavage Site	Cleavage type	Evidence	P4	P3	P2	P1	P1'	P2'	P3'	P4'	Reference	CutDB	MERNUM
lantibiotic mutacin III precursor	O68586	1-63	peptide-Arg41+Phe-peptide	P		Pro	Asp	Thr	Arg	Phe	Lys	Ser	Trp		17553
lantibiotic mutacin-1140	O68586	1-63	peptide-Ala33+Ser-peptide	P	MS	Thr	Ile	Val	Ala	Ser	Asn	Asp	Asp	Escano et al., 2015