Substrates for peptidase S08.013: subtilisin-like peptidase 2 (Plasmodium-type)

Summary Alignment Sequences Sequence features Distribution Literature Substrates

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are thought to be pathologically relevant are indicated by D. Peptide and protein substrates that are not physiologically relevant are indicated by N. Synthetic substrates are indicated by S. Click on the symbol to show only physiological, non-physiological or synthetic substrates, or here to display all substrates. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a protein substrate, click on the UniProt Accession.

Substrate Uniprot Residue range Cleavage Site Cleavage type Evidence P4 P3 P2 P1 P1' P2' P3' P4' Reference CutDB MERNUM
AMA1 apical membrane antigen 1 precursor P22621 25-622 peptide-Leu463+Asn-peptide P Arg Ile Lys Leu Asn Asp Asn Asp Harris et al., 2005 21177
AMA1 apical membrane antigen 1 precursor P22621 25-622 peptide-Thr517+Ser-peptide P Ala Glu Val Thr Ser Asn Asn Glu Harris et al., 2005 21327
merozoite surface protein 1 P04933 20-1618 peptide-Leu1606+Asn-peptide P Gln Gly Met Leu Asn Ile Ser Gln Green et al., 2006 21328