Substrates for peptidase S06.006: Hap serine peptidase

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are thought to be pathologically relevant are indicated by D. Peptide and protein substrates that are not physiologically relevant are indicated by N. Synthetic substrates are indicated by S. Click on the symbol to show only physiological, non-physiological or synthetic substrates, or here to display all substrates. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a protein substrate, click on the UniProt Accession.

Substrate	Uniprot	Residue range	Cleavage Site	Cleavage type	P4	P3	P2	P1	P1'	P2'	P3'	P4'	Reference	CutDB
hap adhesin	Q8GQP2	26-1391	peptide-Phe1025+Ser-peptide	P	Arg	Ala	Val	Phe	Ser	Asp	Pro	Leu	Fink et al., 2001	17465
hap adhesin	P45387	26-1394	peptide-Phe1075+Ala-peptide	P	Gln	Ser	Leu	Phe	Ala	Leu	Glu	Ala	Fink et al., 2001	17466
Hap serine peptidase	P45387	26-1394	peptide-Leu1034+Asn-peptide	P	Gln	Ser	Leu	Leu	Asn	Ala	Leu	Glu	Fink & St Geme, 2003	17463
Hap serine peptidase	P45387	26-1394	peptide-Leu1044+Thr-peptide	N	Gln	Ala	Glu	Leu	Thr	Ala	Glu	Thr	Fink et al., 2001	17464