Substrates for peptidase S06.005: Pic peptidase

Summary Alignment Tree Sequences Sequence features Distribution Literature Substrates Inhibitors

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are thought to be pathologically relevant are indicated by D. Peptide and protein substrates that are not physiologically relevant are indicated by N. Synthetic substrates are indicated by S. Click on the symbol to show only physiological, non-physiological or synthetic substrates, or here to display all substrates. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a protein substrate, click on the UniProt Accession.

Substrate Uniprot Residue range Cleavage Site Cleavage type Evidence P4 P3 P2 P1 P1' P2' P3' P4' Reference CutDB MERNUM
Abz-GLARSNLDEIIAQ-EDDnp Abz-GLA+RSNLDEIIAQ-EDDnp S Abz Gly Leu Ala Arg Ser Asn Leu Abreu et al., 2015
Abz-GLARSNLDEIIAQ-EDDnp Abz-GLAR+SNLDEIIAQ-EDDnp S Gly Leu Ala Arg Ser Asn Leu Asp Abreu et al., 2015
Abz-GLARSNLDEIIAQ-EDDnp Abz-GLARSNLDEIIA+Q-EDDnp S Glu Ile Ile Ala Gln EDD - - Abreu et al., 2015
Abz-KLSINTHPSQKPLQ-EDDnp Abz-KLSINTHPSQ+KPLQ-EDDnp S His Pro Ser Gln Lys Pro Leu Gln Abreu et al., 2015
Abz-KLSINTHPSQKPLQ-EDDnp Abz-KLSINTHPSQK+PLQ-EDDnp S Pro Ser Gln Lys Pro Leu Gln EDD Abreu et al., 2015
Abz-LNEQRYYGGGYGQ-EDDnp Abz-LNE+QRYYGGGYGQ-EDDnp S Abz Leu Asn Glu Gln Arg Tyr Tyr Abreu et al., 2015
Abz-LNEQRYYGGGYGQ-EDDnp Abz-LNEQRYYGGGY+GQ-EDDnp S Gly Gly Gly Tyr Gly Gln EDD - Abreu et al., 2015
Abz-SLQLPSRSSKIQ-EDDnp Abz-SLQ+LPSRSSKIQ-EDDnp S Abz Ser Leu Gln Leu Pro Ser Arg Abreu et al., 2015
Abz-SLQLPSRSSKIQ-EDDnp Abz-SLQLP+SRSSKIQ-EDDnp S Leu Gln Leu Pro Ser Arg Ser Ser Abreu et al., 2015