Substrates for peptidase S01.526: SplD peptidase (Staphylococcus aureus)

Summary Alignment Sequences Sequence features Distribution Structure Literature Substrates

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are thought to be pathologically relevant are indicated by D. Peptide and protein substrates that are not physiologically relevant are indicated by N. Synthetic substrates are indicated by S. Click on the symbol to show only physiological, non-physiological or synthetic substrates, or here to display all substrates. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a protein substrate, click on the UniProt Accession.

Substrate	Uniprot	Residue range	Cleavage Site	Cleavage type	P4	P3	P2	P1	P1'	P2'	P3'	P4'	Reference
beta-casein	P02666	16-224	peptide-Val131+Glu-peptide	N	Lys	Tyr	Pro	Val	Glu	Pro	Phe	Thr	Zdzalik et al., 2013
beta-casein	P02666	16-224	peptide-Thr143+Asp-peptide	N	Leu	Thr	Leu	Thr	Asp	Val	Glu	Asn	Zdzalik et al., 2013
beta-casein	P02666	16-224	peptide-Gln69+Thr-peptide	N	Pro	Phe	Ala	Gln	Thr	Gln	Ser	Leu	Zdzalik et al., 2013
beta-casein	P02666	16-224	peptide-Val99+Pro-peptide	N	Pro	Val	Val	Val	Pro	Pro	Phe	Leu	Zdzalik et al., 2013
CLiPS peptide			peptide-Thr+Tyr+Pro+Ile+Ser-peptide	S	Thr	Tyr	Pro	Ile	Ser	CPe	-	-	Zdzalik et al., 2013
CLiPS peptide			peptide-Val+Tyr+Gly+Ile+Ser-peptide	S	Val	Tyr	Gly	Ile	Ser	CPe	-	-	Zdzalik et al., 2013
CLiPS peptide			peptide-Leu+Tyr+Pro+Ile+Ser-peptide	S	Leu	Tyr	Pro	Ile	Ser	CPe	-	-	Zdzalik et al., 2013
CLiPS peptide			peptide-Arg+Trp+Leu+Leu+Ser-peptide	S	Arg	Trp	Leu	Leu	Ser	CPe	-	-	Zdzalik et al., 2013
CLiPS peptide			peptide-Thr+His+Ile+Leu+Ser-peptide	S	Thr	His	Ile	Leu	Ser	CPe	-	-	Zdzalik et al., 2013
CLiPS peptide			peptide-Arg+Tyr+Leu+Leu+Thr-peptide	S	Arg	Tyr	Leu	Leu	Thr	CPe	-	-	Zdzalik et al., 2013
CLiPS peptide			peptide-Gln+Trp+Leu+Leu+Ala-peptide	S	Gln	Trp	Leu	Leu	Ala	CPe	-	-	Zdzalik et al., 2013
CLiPS peptide			peptide-Gln+Tyr+Leu+Leu+Gly-peptide	S	Gln	Tyr	Leu	Leu	Gly	CPe	-	-	Zdzalik et al., 2013
CLiPS peptide			peptide-Val+Tyr+Ser+Thr+Ser-peptide	S	Val	Tyr	Ser	Thr	Ser	CPe	-	-	Zdzalik et al., 2013
CLiPS peptide			peptide-Arg+Tyr+Trp+Thr+Ser-peptide	S	Arg	Tyr	Trp	Thr	Ser	CPe	-	-	Zdzalik et al., 2013
CLiPS peptide			peptide-Arg+Tyr+Pro+Thr+Ser-peptide	S	Arg	Tyr	Pro	Thr	Ser	CPe	-	-	Zdzalik et al., 2013
CLiPS peptide			peptide-Arg+Trp+Pro+Thr+Ser-peptide	S	Arg	Trp	Pro	Thr	Ser	CPe	-	-	Zdzalik et al., 2013
CLiPS peptide			peptide-Arg+Tyr+Leu+Thr+Ser-peptide	S	Arg	Tyr	Leu	Thr	Ser	CPe	-	-	Zdzalik et al., 2013
CLiPS peptide			peptide-Arg+Tyr+Leu+Thr+Gly-peptide	S	Arg	Tyr	Leu	Thr	Gly	CPe	-	-	Zdzalik et al., 2013
CLiPS peptide			peptide-Arg+Tyr+Pro+Thr+Ser-peptide	S	Arg	Tyr	Pro	Thr	Ser	CPe	-	-	Zdzalik et al., 2013
CLiPS peptide			peptide-Leu+Phe+Pro+Val+Ser-peptide	S	Leu	Phe	Pro	Val	Ser	CPe	-	-	Zdzalik et al., 2013
CLiPS peptide			peptide-Val+Tyr+Pro+Val+Asp-peptide	S	Val	Tyr	Pro	Val	Asp	CPe	-	-	Zdzalik et al., 2013
CLiPS peptide			peptide-Met+Trp+Gln+Val+Ser-peptide	S	Met	Trp	Gln	Val	Ser	CPe	-	-	Zdzalik et al., 2013