Substrates for peptidase S01.413: prophenoloxidase-activating peptidase (Pacifastacus leniusculus)

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Literature Substrates

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are thought to be pathologically relevant are indicated by D. Peptide and protein substrates that are not physiologically relevant are indicated by N. Synthetic substrates are indicated by S. Click on the symbol to show only physiological, non-physiological or synthetic substrates, or here to display all substrates. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a protein substrate, click on the UniProt Accession.

Substrate Uniprot Residue range Cleavage Site Cleavage type Evidence P4 P3 P2 P1 P1' P2' P3' P4' Reference CutDB MERNUM
prophenoloxidase Q26060 1-706 peptide-Arg176+Thr-peptide P NT Glu Val Asn Arg Thr Pro Pro Thr Aspan et al., 1995
S-2337 Bz-Ile-Glu-Pid-Gly-Arg+NHPhNO2 S Glu Pid Gly Arg NAN - - - Aspan & Soderhall, 1991
serine protease Q9U0G3 1-468 peptide-Arg236+Ile-peptide P NT Pro Pro Thr Arg Ile Val Gly Gly Wang et al. 2001