Substrates for peptidase S01.312: SplE peptidase (Staphylococcus aureus)

Summary Alignment Sequences Sequence features Distribution Structure Literature Substrates

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are thought to be pathologically relevant are indicated by D. Peptide and protein substrates that are not physiologically relevant are indicated by N. Synthetic substrates are indicated by S. Click on the symbol to show only physiological, non-physiological or synthetic substrates, or here to display all substrates. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a protein substrate, click on the UniProt Accession.

Substrate	Cleavage Site	Cleavage type	P4	P3	P2	P1	P1'	P2'	P3'	P4'	Reference
Ac-Leu-Trp-Leu-His-ACC	Ac-Leu-Trp-Leu-His-ACC	S	Leu	Trp	Leu	His	ACC	-	-	-	Stach et al., 2018
CLIPS peptide	peptide-His+Gly-peptide	S	Val	Phe	Leu	His	Gly	CPe	-	-	Stach et al., 2018
CLIPS peptide	peptide-His+Ser-peptide	S	Ser	Tyr	Leu	His	Ser	CPe	-	-	Stach et al., 2018
CLIPS peptide	peptide-His+Gly-peptide	S	Thr	Tyr	Leu	His	Gly	CPe	-	-	Stach et al., 2018
CLIPS peptide	peptide-His+Ser-peptide	S	Met	Tyr	Leu	His	Ser	CPe	-	-	Stach et al., 2018
CLIPS peptide	peptide-His+Ser-peptide	S	Leu	His	Leu	His	Ser	CPe	-	-	Stach et al., 2018
CLIPS peptide	peptide-His+Ser-peptide	S	Leu	Val	Leu	His	Ser	CPe	-	-	Stach et al., 2018
CLIPS peptide	peptide-His+Gly-peptide	S	Ile	Phe	Pro	His	Gly	CPe	-	-	Stach et al., 2018
CLIPS peptide	peptide-His+Ala-peptide	S	Val	Trp	Val	His	Ala	CPe	-	-	Stach et al., 2018
CLIPS peptide	peptide-His+Tyr-peptide	S	Gly	Gly	Ile	His	Tyr	CPe	-	-	Stach et al., 2018
CLIPS peptide	peptide-His+Ser-peptide	S	Pro	Phe	Phe	His	Ser	CPe	-	-	Stach et al., 2018
CLIPS peptide	peptide-His+Thr-peptide	S	Gly	Ala	Met	His	Thr	CPe	-	-	Stach et al., 2018
CLIPS peptide	peptide-His+Leu-peptide	S	Arg	Ala	Val	His	Leu	CPe	-	-	Stach et al., 2018
CLIPS peptide	peptide-Gln+Asn-peptide	S	Leu	Trp	Leu	Gln	Asn	CPe	-	-	Stach et al., 2018
CLIPS peptide	peptide-Gln+Gly-peptide	S	Leu	Phe	Leu	Gln	Gly	CPe	-	-	Stach et al., 2018
CLIPS peptide	peptide-Gln+Ser-peptide	S	Leu	Tyr	Leu	Gln	Ser	CPe	-	-	Stach et al., 2018
CLIPS peptide	peptide-Gln+Ser-peptide	S	Val	Tyr	Leu	Gln	Ser	CPe	-	-	Stach et al., 2018
CLIPS peptide	peptide-Gln+Arg-peptide	S	Val	Tyr	Leu	Gln	Arg	CPe	-	-	Stach et al., 2018
CLIPS peptide	peptide-Gln+Gly-peptide	S	Val	Tyr	Leu	Gln	Gly	CPe	-	-	Stach et al., 2018
CLIPS peptide	peptide-Gln+Ser-peptide	S	Thr	Phe	Leu	Gln	Ser	CPe	-	-	Stach et al., 2018
CLIPS peptide	peptide-Gln+Asp-peptide	S	Phe	Trp	Leu	Gln	Asp	CPe	-	-	Stach et al., 2018
CLIPS peptide	peptide-Gln+Leu-peptide	S	Thr	Trp	Leu	Gln	Leu	CPe	-	-	Stach et al., 2018
CLIPS peptide	peptide-Gln+Ser-peptide	S	Val	Val	Leu	Gln	Ser	CPe	-	-	Stach et al., 2018
CLIPS peptide	peptide-Gln+Gly-peptide	S	Val	Tyr	Met	Gln	Gly	CPe	-	-	Stach et al., 2018
CLIPS peptide	peptide-Gln+Gly-peptide	S	Ile	Trp	Tyr	Gln	Gly	CPe	-	-	Stach et al., 2018
CLIPS peptide	peptide-Leu+Arg-peptide	S	Glu	Leu	Leu	Arg	Gly	CPe	-	-	Stach et al., 2018
CLIPS peptide	peptide-Leu+Arg-peptide	S	Arg	Leu	Leu	Arg	Tyr	CPe	-	-	Stach et al., 2018