Substrates for peptidase S01.220: coagulation factor B (Limulus, Tachypleus), activated

Summary Alignment Tree Sequences Sequence features Distribution Literature Substrates

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are thought to be pathologically relevant are indicated by D. Peptide and protein substrates that are not physiologically relevant are indicated by N. Synthetic substrates are indicated by S. Click on the symbol to show only physiological, non-physiological or synthetic substrates, or here to display all substrates. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a protein substrate, click on the UniProt Accession.

Substrate Uniprot Residue range Cleavage Site Cleavage type Evidence P4 P3 P2 P1 P1' P2' P3' P4' Reference CutDB MERNUM
Boc-Met-Thr-Arg-NHMec Boc-Met-Thr-Arg+NHMec S Boc Met Thr Arg AMC - - - Kawabata et al., 2004
Bz-Ser-Thr-Arg-NHMec Bz-Ser-Thr-Arg+NHMec S Bz Ser Thr Arg AMC - - - Kawabata et al., 2004
Bz-Thr-Thr-Arg-NHMec Bz-Thr-Thr-Arg+NHMec S Bz Thr Thr Arg AMC - - - Kawabata et al., 2004
clotting enzyme ({Tachypleus}) P21902 30-375 peptide-Arg98+Ile-peptide P Thr Thr Thr Arg Ile Ile Gly Gly Kawabata et al., 2004 17415