Substrates for peptidase S01.219: coagulation factor C (Limulus, Tachypleus), activated

Summary Alignment Tree Sequences Sequence features Distribution Literature Substrates

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are thought to be pathologically relevant are indicated by D. Peptide and protein substrates that are not physiologically relevant are indicated by N. Synthetic substrates are indicated by S. Click on the symbol to show only physiological, non-physiological or synthetic substrates, or here to display all substrates. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a protein substrate, click on the UniProt Accession.

Substrate	Uniprot	Residue range	Cleavage Site	Cleavage type	P4	P3	P2	P1	P1'	P2'	P3'	P4'	Reference	CutDB
Boc-Val-Pro-Arg-NHMec			Boc-Val-Pro-Arg+NHMec	S	Boc	Val	Pro	Arg	AMC	-	-	-	Kawabata et al., 2004
Boc-Val-Pro-Arg-NHPhNO2			Boc-Val-Pro-Arg+NHPhNO2	S	Boc	Val	Pro	Arg	NAN	-	-	-	Kawabata et al., 2004
limulus coagulation factor B	Q27081	24-400	peptide-Arg103+Ser104-peptide	P	Thr	Val	Gly	Arg	Ser	Gly	Ser	Pro	Kawabata et al., 2004	17413
limulus coagulation factor B	Q27081	24-400	peptide-Ile124+Ile125-peptide	P	Gly	Arg	Gly	Ile	Ile	Ala	Gly	Gly	Kawabata et al., 2004	17414