Substrates for peptidase S01.154: pancreatic endopeptidase E

Summary Alignment Tree Sequences Sequence features Distribution Literature Substrates Pharma

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are thought to be pathologically relevant are indicated by D. Peptide and protein substrates that are not physiologically relevant are indicated by N. Synthetic substrates are indicated by S. Click on the symbol to show only physiological, non-physiological or synthetic substrates, or here to display all substrates. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a protein substrate, click on the UniProt Accession.

Substrate Uniprot Residue range Cleavage Site Cleavage type Evidence P4 P3 P2 P1 P1' P2' P3' P4' Reference CutDB MERNUM
Ac-Ala-Ala-Ala-OMe Ac-Ala-Ala-Ala+OMe S Ac Ala Ala Ala OMe - - - Bieth, 2004
pancreatic endopeptidase E peptide-Val13+Asn14-peptide N Ser Arg Val Val Asn Gly Glu Asp Bieth, 2004
Suc-Ala-Ala-Ala-NHPhNO2 Suc-Ala-Ala-Ala+NHPhNO2 S Suc Ala Ala Ala NAN - - - Bieth, 2004