Substrates for peptidase S01.042: intestinal serine peptidase (rodent)

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Literature Substrates Inhibitors

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are thought to be pathologically relevant are indicated by D. Peptide and protein substrates that are not physiologically relevant are indicated by N. Synthetic substrates are indicated by S. Click on the symbol to show only physiological, non-physiological or synthetic substrates, or here to display all substrates. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a protein substrate, click on the UniProt Accession.

Substrate	Cleavage Site	Cleavage type	P4	P3	P2	P1	P1'	P2'	P3'	P4'	Reference
Boc-Gln-Ala-Arg-NHMec	Boc-Gln-Ala-Arg+NHMec	S	Boc	Gln	Ala	Arg	AMC	-	-	-	Okumura et al., 2003
Boc-Gln-Gly-Arg-NHMec	Boc-Gln-Gly-Arg+NHMec	S	Boc	Gln	Gly	Arg	AMC	-	-	-	Okumura et al., 2003
Boc-Glu(OBzl)-Ala-Arg-NHMec	Boc-Glu(OBzl)-Ala-Arg+NHMec	S	Boc	GlB	Ala	Arg	AMC	-	-	-	Okumura et al., 2003
Boc-Glu(OBzl)-Gly-Arg-NHMec	Boc-Glu(OBzl)-Gly-Arg+NHMec	S	Boc	GlB	Gly	Arg	AMC	-	-	-	Okumura et al., 2003
Boc-Ile-Glu-Gly-Arg-NHMec	Boc-Ile-Glu-Gly-Arg+NHMec	S	Ile	Glu	Gly	Arg	AMC	-	-	-	Okumura et al., 2003
Boc-Phe-Ser-Arg-NHMec	Boc-Phe-Ser-Arg+NHMec	S	Boc	Phe	Ser	Arg	AMC	-	-	-	Okumura et al., 2003