Substrates for peptidase S01.039: kallikrein 1-related peptidase b22 (Mus musculus)

Summary Gene structure Alignment Sequences Sequence features Distribution Literature Substrates

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are thought to be pathologically relevant are indicated by D. Peptide and protein substrates that are not physiologically relevant are indicated by N. Synthetic substrates are indicated by S. Click on the symbol to show only physiological, non-physiological or synthetic substrates, or here to display all substrates. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a protein substrate, click on the UniProt Accession.

Substrate	Uniprot	Residue range	Cleavage Site	Cleavage type	P4	P3	P2	P1	P1'	P2'	P3'	P4'	Reference
Boc-Arg-Val-Arg-Arg-NHMec			Boc-Arg-Val-Arg-Arg-NHMec	S	Boc	Arg	Val	Arg	AMC	-	-	-	Kikkawa et al., 1998
Boc-Gln-Arg-Arg-NHMec			Boc-Gln-Arg-Arg-NHMec	S	Boc	Gln	Arg	Arg	AMC	-	-	-	Kikkawa et al., 1998
Boc-Glu-Lys-Lys-NHMec			Boc-Glu-Lys-Lys+NHMec	S	Boc	Glu	Lys	Lys	AMC	-	-	-	Kikkawa et al., 1998
Boc-Leu-Lys-Arg-NHMec			Boc-Leu-Lys-Arg-NHMec	S	Boc	Leu	Lys	Arg	AMC	-	-	-	Kikkawa et al., 1998
Pyr-Arg-Thr-Lys-Arg-NHMec			Pyr-Arg-Thr-Lys-Arg-NHMec	S	Arg	Thr	Lys	Arg	AMC	-	-	-	Kikkawa et al., 1998
renin-2 precursor	P00796	26-401	peptide-Arg63+Ser-peptide	P	Phe	Thr	Lys	Arg	Ser	Ser	Leu	Thr	Kikkawa et al., 1998
renin-2 precursor	P00796	26-401	peptide-Lys62+Arg-peptide	P	Val	Phe	Thr	Lys	Arg	Ser	Ser	Leu	Kikkawa et al., 1998