Substrates for peptidase N10.006: intein-containing DNA polymerase II large subunit DP2 precursor Mername-AA282

Summary Alignment Tree Sequences Sequence features Distribution Substrates

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are thought to be pathologically relevant are indicated by D. Peptide and protein substrates that are not physiologically relevant are indicated by N. Synthetic substrates are indicated by S. Click on the symbol to show only physiological, non-physiological or synthetic substrates, or here to display all substrates. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a protein substrate, click on the UniProt Accession.

Substrate	Uniprot	Residue range	Cleavage Site	Cleavage type	Evidence	P4	P3	P2	P1	P1'	P2'	P3'	P4'
dNA polymerase II large subunit	Q5UZ40	1-1395	peptide-Asn965+Cys-peptide	N	CS	Lys	Arg	Arg	Asn	Cys	Phe	His	Pro
dNA polymerase II large subunit	Q5UZ40	1-1395	peptide-Gln1145+Cys-peptide	N	CS	Tyr	Val	Gly	Gln	Cys	Asp	Gly	Asp
dNA polymerase II large subunit	A7I4I9	1-1307	peptide-Asn886+Cys-peptide	N	CS	Lys	Arg	Arg	Asn	Cys	Phe	Tyr	Gly
dNA polymerase II large subunit	A7I4I9	1-1307	peptide-Gln1051+Cys-peptide	N	CS	Phe	Thr	Gly	Gln	Cys	Asp	Gly	Asp
DNA polymerase II large subunit	D3SVF8	1-1481	peptide-Asn1020+Cys-peptide	N	CS	Lys	Arg	Arg	Asn	Cys	Phe	His	Pro
DNA polymerase II large subunit	D3SVF8	1-1481	peptide-Gln1233+Cys-peptide	N	CS	Ile	Thr	Gly	Gln	Cys	Asp	Gly	Asp
dNA polymerase II large subunit	Q2FSF9	1-1286	peptide-Asn872+Cys-peptide	N	CS	Lys	Arg	Arg	Asn	Cys	Phe	His	Gly
dNA polymerase II large subunit	Q2FSF9	1-1286	peptide-Gln1037+Cys-peptide	N	CS	Phe	Thr	Gly	Gln	Cys	Asp	Gly	Asp
dNA polymerase II large subunit	A3CXE7	1-1285	peptide-Asn870+Cys-peptide	N	CS	Lys	Arg	Arg	Asn	Cys	Phe	Ala	Gly
dNA polymerase II large subunit	A3CXE7	1-1285	peptide-Gln1035+Cys-peptide	N	CS	Phe	Cys	Gly	Gln	Cys	Asp	Gly	Asp
dNA polymerase II large subunit	Q9HMX8	1-1370	peptide-Asn925+Cys-peptide	N	CS	Lys	Arg	Arg	Asn	Cys	Phe	His	Pro
dNA polymerase II large subunit	Q9HMX8	1-1370	peptide-Gln1120+Cys-peptide	N	CS	Phe	Thr	Gly	Gln	Cys	Asp	Gly	Asp
dNA polymerase II, large subunit DP2	B8GE46	1-1283	peptide-Asn868+Cys-peptide	N	CS	Lys	Arg	Arg	Asn	Cys	Phe	Tyr	Gly
dNA polymerase II, large subunit DP2	B8GE46	1-1283	peptide-Gln1033+Cys-peptide	N	CS	Phe	Thr	Gly	Gln	Cys	Asp	Gly	Asp
DNA polymerase II, large subunit DP2	C7NZY6	1-1373	peptide-Asn941+Cys-peptide	N	CS	Lys	Arg	Arg	Asn	Cys	Phe	His	Pro
DNA polymerase II, large subunit DP2	C7NZY6	1-1373	peptide-Gln1123+Cys-peptide	N	CS	Tyr	Ser	Gly	Gln	Cys	Asp	Gly	Asp
dNA polymerase II, large subunit DP2	B9LRD2	1-1366	peptide-Asn938+Cys-peptide	N	CS	Lys	Arg	Arg	Asn	Cys	Phe	His	Pro
dNA polymerase II, large subunit DP2	B9LRD2	1-1366	peptide-Gln1116+Cys-peptide	N	CS	Leu	Val	Ala	Gln	Cys	Asp	Gly	Asp