Substrates for peptidase N10.005: intein-containing DNA polymerase II large subunit DP2 precursor Mername-AA281

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are thought to be pathologically relevant are indicated by D. Peptide and protein substrates that are not physiologically relevant are indicated by N. Synthetic substrates are indicated by S. Click on the symbol to show only physiological, non-physiological or synthetic substrates, or here to display all substrates. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a protein substrate, click on the UniProt Accession.

Substrate	Uniprot	Residue range	Cleavage Site	Cleavage type	Evidence	P4	P3	P2	P1	P1'	P2'	P3'	P4'
DNA polymerase II large subunit	C6A4U4	1-1442	peptide-Asn948+Cys-peptide	N	CS	Lys	Arg	Arg	Asn	Cys	Phe	Pro	Gly
DNA polymerase II large subunit	C6A4U4	1-1442	peptide-Gln1114+Cys-peptide	N	CS	Val	Thr	His	Gln	Cys	Asp	Gly	Asp
DNA polymerase II large subunit	O57861	1-1431	peptide-Pro954+Gly-peptide	N	CS	Asn	Cys	Phe	Pro	Gly	Asp	Thr	Arg
DNA polymerase II large subunit	O57861	1-1431	peptide-Gly1120+Asp-peptide	N	CS	Gln	Cys	Asp	Gly	Asp	Glu	Asp	Ala
dNA polymerase II large subunit	Q5JET0	1-1798	peptide-Asn963+Cys-peptide	N	CS	Lys	Arg	Arg	Asn	Cys	Phe	Pro	Gly
dNA polymerase II large subunit	Q5JET0	1-1798	peptide-Gln1437+Cys-peptide	N	CS	Val	Thr	His	Gln	Cys	Asp	Gly	Asp
dNA polymerase II large subunit	Q9V2F4	1-1455	peptide-Asn954+Cys-peptide	N	CS	Lys	Arg	Arg	Asn	Cys	Phe	Pro	Gly
dNA polymerase II large subunit	Q9V2F4	1-1455	peptide-Gln1139+Cys-peptide	N	CS	Val	Thr	His	Gln	Cys	Asp	Gly	Asp
DNA polymerase II large subunit DP2, intein containing	C5A316	1-1459	peptide-Asn961+Cys-peptide	N	CS	Lys	Arg	Arg	Asn	Cys	Phe	Pro	Gly
DNA polymerase II large subunit DP2, intein containing	C5A316	1-1459	peptide-Gln1125+Cys-peptide	N	CS	Val	Thr	His	Gln	Cys	Asp	Gly	Asp
dNA polymerase II, large subunit DP2	D5VTT0	1-1289	peptide-Asn870+Cys-peptide	N	CS	Lys	Arg	Arg	Asn	Cys	Phe	Thr	Glu
dNA polymerase II, large subunit DP2	D5VTT0	1-1289	peptide-Gln1038+Cys-peptide	N	CS	Leu	Leu	Ala	Gln	Cys	Asp	Gly	Asp
dNA polymerase II, large subunit DP2	C9RGL5	1-1609	peptide-Asn883+Cys-peptide	N	CS	Lys	Arg	Arg	Asn	Cys	Phe	Pro	Gly
dNA polymerase II, large subunit DP2	C9RGL5	1-1609	peptide-Gln1357+Cys-peptide	N	CS	Gln	Thr	Phe	Gln	Cys	Asp	Gly	Asp
DNA polymerase II, large subunit DP2	D3S8H3	1-1620	peptide-Asn884+Cys-peptide	N	CS	Lys	Arg	Arg	Asn	Cys	Phe	Pro	Gly
DNA polymerase II, large subunit DP2	D3S8H3	1-1620	peptide-Gln1368+Cys-peptide	N	CS	Gln	Thr	Tyr	Gln	Cys	Asp	Gly	Asp
dNA polymerase II, small subunit	B6YUE7	1-1771	peptide-Asn960+Cys-peptide	N	CS	Lys	Arg	Arg	Asn	Cys	Phe	Pro	Gly
dNA polymerase II, small subunit	B6YUE7	1-1771	peptide-Gln1434+Cys-peptide	N	CS	Val	Thr	His	Gln	Cys	Asp	Gly	Asp
NDP-sugar dehydrogenase, containing HINT/DOD homing endonuclease intein	C5A2Z3	1-919	peptide-His279+Cys-peptide	N	CS	Val	Gly	Gly	His	Cys	Phe	Ala	Lys
NDP-sugar dehydrogenase, containing HINT/DOD homing endonuclease intein	C5A2Z3	1-919	peptide-Asn747+Cys-peptide	N	CS	Ile	Val	His	Asn	Cys	Ile	Pro	Val
nucleotide sugar dehydrogenase	C9REC8	1-899	peptide-Ser261+Cys-peptide	N	CS	Tyr	Gly	Gly	Ser	Cys	Phe	His	Pro
nucleotide sugar dehydrogenase	C9REC8	1-899	peptide-Asn715+Cys-peptide	N	CS	Leu	Ile	His	Asn	Cys	Phe	Pro	Lys
UDP-glucose 6-dehydrogenase	A6UU28	1-906	peptide-Ser260+Cys-peptide	N	CS	Tyr	Gly	Gly	Ser	Cys	Phe	His	Pro
UDP-glucose 6-dehydrogenase	A6UU28	1-906	peptide-Asn723+Cys-peptide	N	CS	Leu	Ile	His	Asn	Cys	Phe	Pro	Lys
uncharacterized protein MJ1054	Q58454	1-895	peptide-Ser260+Cys-peptide	N	CS	Tyr	Gly	Gly	Ser	Cys	Phe	His	Pro
uncharacterized protein MJ1054	Q58454	1-895	peptide-Asn714+Cys-peptide	N	CS	Leu	Ile	His	Asn	Cys	Phe	Pro	Lys